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Articles by Ge Jin
Epithelial inflammatory memory in ulcerative colitis: molecular mechanisms and translational implications
Abstract Ulcerative colitis (UC) can relapse after clinical and endoscopic remission, raising the question of whether previously inflamed epithelium retains altered responsiveness. Patient-derived colonic organoids and lineage-resolved colitis models show that inflammation-associated chromatin accessibility can persist after removal of the original environment and influence subsequent epithelial behavior.
PD-1 regulates CD4 + T cell-mediated CD8 + T cell responses in the brain to balance viral control and neuroinflammation
Abstract Programmed cell death protein 1 (PD-1) is expressed by T cells during progressive multifocal leukoencephalopathy (PML), a life-threatening brain disease caused by the human-only JC polyomavirus (JCPyV). PD-1 checkpoint immunotherapy has benefited some PML patients, but reasons for its variable outcomes are unclear.
RNF2 mediates H2A ubiquitination to promote colitis via suppressing monocyte-macrophage transition in mice
Abstract Monocyte-macrophage transition is dysregulated in inflammatory bowel disease. While polycomb repressive complexes are crucial for maintaining cellular identity, their specific roles in colitis are poorly defined. Here, we show that Ring finger protein 2, a core catalytic subunit of polycomb repressive complex 1, regulates the monocyte-macrophage transition during colitis. It is highly expressed in the immature colon and circulating monocytes during ulcerative colitis.
An interpretable memory forensics framework for unknown attack identification in power grid edge devices
Abstract With the application of domestic trusted operating systems in the field of power grid, the security threats it faces are increasingly complex. Aiming at the security protection requirements of power grid edge equipment operating system, a comprehensive framework integrating memory forensics and malicious attack type discrimination is proposed.
Characteristics of Coronary Intra- or Extramedial Hematomas Causing Emergent Return to Catheterization Laboratory After Percutaneous Coronary Intervention
JACC Journals › JACC: Cardiovascular Interventions › Archives › Vol. 19 No. 10 Share on : JACC: Cardiovascular Interventions Volume 19, Number 10 Get full access to this article View all available purchase options and get full access to this article. Supplementary Material Supplemental Tables 1-7 and Supplemental Figures 1-6 (mmc1.docx) References 1.
Optimal Design of One-Sided Exponential Adaptive EWMA Scheme Based on Median Run Length
1. Introduction Quality control is essential for manufacturing and service industries to ensure product qualify and enhance operational efficiency [1]. Statistical process control (SPC) serves as a critical tool in ensuring product quality by monitoring and controlling the state of processes [2]. Among various SPC tools, monitoring schemes are extensively used to identify shifts in process parameters.
Long-term distributed temperature sensing monitoring for near-wellbore gas migration and gas hydrate formation
Links More information: Publisher Index Page (via DOI) Download citation as: RIS | Dublin Core Study Area Publication type Article Publication Subtype Journal Article Title Long-term distributed temperature sensing monitoring for near-wellbore gas migration and gas hydrate formation Series title Society of Petroleum Engineers journal DOI 10.2118/223111-PA Edition Online First Year Published 2024 Language English Publisher Society of Petroleum Engineers Contributing office(s) Central Energy...
BPT-PLR: A Balanced Partitioning and Training Framework with Pseudo-Label Relaxed Contrastive Loss for Noisy Label Learning
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Characterization of Gas-Liquid Two-Phase Slug Flow Using Distributed Acoustic Sensing in Horizontal Pipes
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
High-order magnetic resonance in the presence of strong longitudinal radio-frequency magnetic field based on atomic alignment states
A longitudinal radio-frequency (rf) magnetic field resonating at the Larmor frequency along the ẑ direction in the presence of a static transverse magnetic field s investigated. Optical-radio-frequency double resonance in Rb85 characterizes the strength of an external magnetic field through the precession frequency of Rb85 atoms. The measurements are carried out in a paraffin-coated Rb85 cell with a spin alignment configuration.
EpMYB2 positively regulates chicoric acid biosynthesis by activating both primary and specialized metabolic genes in purple coneflower
CONFLICT OF INTEREST The authors declare no conflict of interest. Supporting Information Filename Description tpj16759-sup-0001-Figures.docxWord 2007 document , 3.6 MB Figure S1. RT–qPCR confirms chicoric acid biosynthetic gene expression patterns from RNA-seq. Figure S2. Candidate chicoric acid biosynthesis regulator is identified by co-expression and phylogenetic analysis. Figure S3. EpMYB2 is an R2R3-MYB. Figure S4. Construction and identification of positive transgenic purple coneflower calli.
A Modified Method for Transient Transformation via Pollen Magnetofection in Lilium Germplasm
1. Introduction Plant genetic transformation is an important pathway to improve plant yield, quality, and tolerance to abiotic/biotic stress [1]. Plant transformation is a complex process that involves the preparation of explants, delivery of genes of interest into plant cells via Agrobacterium- or biolistic-mediated methods, selection and regeneration of transgenic plants, and verification of gene integration into the genome through molecular methods.
Strain-based forward modeling and inversion of seismic moment tensors using distributed acoustic sensing (DAS) observations
1 Introduction Anthropogenic earthquakes are a worldwide phenomenon associated with oil and gas production, geothermal projects, carbon capture and storage, and other industrial processes (Ellsworth, 2013; Atkinson et al., 2016). In Canada, induced earthquakes have been associated with a small fraction of hydraulic fracturing operations, including those in the Duvernay and Montney plays.
pTSE: A Multi-model Ensemble Method for Probabilistic Time Series Forecasting
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Congestion Avoidance in Intelligent Transport Networks Based on WSN-IoT through Controlling Data Rate of Zigbee Protocol by Learning Automata
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,2,*, 1,2,*, 1,2 and 1,2 1 State Key Laboratory of Particle Detection and Electronics, University of Science and Technology of China, Hefei 230026, China 2 Department of Modern Physics, University of Science and Technology of China, Hefei 230026, China * Authors to whom correspondence should be addressed.
Clinical study of interstitial brachytherapy for 72 cases of recurrent cervical cancer
Abstract Objective: To determine the application value of interstitial brachytherapy in the treatment of recurrent cervical cancer. Methods: A retrospective analysis was conducted on the clinical data of 72 patients with recurrent cervical cancer admitted to The Fourth Hospital of Hebei Medical University from September 2017 to April 2022. They were divided into two groups according to different brachytherapy methods: conventional after-load radiotherapy group and interstitial brachytherapy group.
Visible light transmittance of micro-pore optic plates for the wide-field x-ray telescope on the Einstein probe
Abstract Micro-pore optics (MPO) has been employed in space x-ray telescopes for large field-of-view observations. For x-ray focal plane detectors with visible photon sensing capability, the optical blocking filter (OBF) on MPO devices is critical for preventing signal contamination by those photons. In this work, we designed a piece of equipment to measure the light transmission with high accuracy.
Remote Interactive Surgery Platform (RISP): Proof of Concept for an Augmented-Reality-Based Platform for Surgical Telementoring
2.3. Platform Requirements During the following step of the planning stage, we defined the requirements for the platform in consensus meetings and by reviewing the literature [11]. These requirements were defined to ensure reliability during use in the above-mentioned applications.
Removing multiple types of noise of distributed acoustic sensing seismic data using attention-guided denoising convolutional neural network
1College of Instrumentation and Electrical Engineering, Jilin University, Changchun, China 2College of Communication Engineering, Jilin University, Changchun, China 3Metis Privatistskole, Bergen, Norway In recent years, distributed optical fiber acoustic sensing (DAS) technology has been increasingly used for vertical seismic profile (VSP) exploration.
Deep Multi-Task Learning for an Autoencoder-Regularized Semantic Segmentation of Fundus Retina Images
Abstract : Automated segmentation of retinal blood vessels is necessary for the diagnosis, monitoring, and treatment planning of the disease. Although current U-shaped structure models have achieved outstanding performance, some challenges still emerge due to the nature of this problem and mainstream models. (1) There does not exist an effective framework to obtain and incorporate features with different spatial and semantic information at multiple levels.
Zero–Waste Recycling of Fiber/Epoxy from Scrap Wind Turbine Blades for Effective Resource Utilization
Abstract : The number of scrap wind turbines is expanding globally as the wind power industry develops rapidly. Zero–waste recycling of scrap wind turbine blades (WTB) is the key for wind power firms to achieve green and sustainable development on the premise of satisfying environmental protection criteria. In this work, the pyrolysis of fiber/epoxy composites obtained from scrap WTB in oxidizing inert atmospheres was investigated.
Fracture Hits and Hydraulic-Fracture Geometry Characterization Using Low-Frequency Distributed Acoustic Sensing Strain Data
The propagation process and geometry of hydraulic fractures depend on complex interactions among the induced fractures and the pre-existing rock fabric, the heterogeneous rock properties, and the stress state. Accurate characterization of the resulting complex hydraulic-fracture geometry remains challenging. Fiber-optic-based distributed acoustic sensing (DAS) measurements have been used for monitoring hydraulic fracturing in adjacent treatment wells.
IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection
High-affinity help CD4 T cells are critical for the development of tissue-resident memory (TRM) CD8 T cells during persistent viral infection of the central nervous system with polyomavirus. Ren et al. identified a role for IL-21 produced by virus-specific high-affinity CD4 T cells in driving differentiation of brain CD8 T cells into TRM. IL21R−/− brain CD8 T cells have defects in antigen recall and oxidative metabolism and fail to differentiate into TRM.
Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor-Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition | The Journal of Immunology
Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor–Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition Rui Chen, Ge Jin, Wei Li, Thomas M. McIntyre The Journal of Immunology October 1, 2018, 201 (7) 2154-2164; DOI: 10.4049/jimmunol.1800124
Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor-Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition | The Journal of Immunology
Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor–Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition Rui Chen, Ge Jin, Wei Li, Thomas M. McIntyre The Journal of Immunology August 27, 2018, ji1800124; DOI: 10.4049/jimmunol.1800124
The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-epidermal growth factor (EGF) to active high-molecular-weight EGF
Platelets are the sole source of EGF in circulation, yet how EGF is stored or released from stimulated cells is undefined. In fact, we found platelets did not store EGF, synthesized as a single 6-kDa domain in pro-EGF, but rather expressed intact pro-EGF precursor on granular and plasma membranes. Activated platelets released high-molecular-weight (HMW)-EGF, produced by a single cleavage between the EGF and the transmembrane domains of pro-EGF.
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