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Articles by Jiani Chen
Plasma metabolomic and lipidomic signatures characteristic of treatment non-response in rheumatoid arthritis
Abstract Objectives: This study aimed to investigate plasma metabolomic and lipidomic profiles in rheumatoid arthritis (RA) to identify potential biomarkers for distinguishing treatment responses. Methods: Plasma samples were collected from 106 RA patients and 10 healthy controls, with 30 RA samples selected based on predefined inclusion criteria.
Host manipulation by Drosophila parasitoid wasps: molecular tools and strategic insights
Keywords parasitoid wasp Drosophila host manipulation genome resource venom protein molecular mechanism Get full text access Log in, subscribe or purchase for full access. References 1. Parasitic Wasps Chapman and Hall, 1997 2. Pennacchio, F. ∙ Strand, M.R. Evolution of developmental strategies in parasitic hymenoptera Annu. Rev. Entomol. 2006; 51:233-258 3. Brodeur, J. ∙ Boivin, G. Functional ecology of immature parasitoids Annu. Rev. Entomol. 2004; 49:27-49 4. Jervis, M.A. ...
Skin Organoids for Disease Modelling, Drug Screening and Regenerative Medicine: Recent Advances and Future Perspectives
Disclosure We declare that during manuscript preparation, we utilised ChatGPT (OpenAI) and DeepSeek (large language models) for wording optimisation and structural refinement, and Grammarly for grammar checks. These tools assisted solely in improving language clarity and organisation, not in generating scientific content, data, figures or references. All content was authored, curated and verified by the authors, who ensure the work's integrity and accuracy.
Petrologic evidence for core sulfur degassing in partially differentiated planetesimals
Abstract Partial differentiation hypothesis is a scenario for interpreting the internal structure of planetesimals and the genetic relationship between chondrites and nonchondrites. However, no petrologic records supporting this hypothesis have been reported yet. Here, we report sulfide replacement textures of melilite and olivine in Ornans-like chondrites, whose occurrences are correlated with the degree of thermal metamorphism of the host chondrites.
Electron Beam Irradiation Modified UiO-66 Supported Pt Catalysts for Low-Temperature Ethyl Acetate Catalytic Degradation
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Captive-rearing changes the gut microbiota of the bumblebee Bombus lantschouensis native to China
Captive-rearing changes the gut microbiota of the bumblebee Bombus lantschouensis native to China College of Science, The Northwest Normal University, Lanzhou, Gansu, China DOI 10.7717/peerj.18964 Academic Editor Travis Beddoe Subject Areas Entomology, Microbiology, Zoology Keywords Gut microbiota, Bumblebee, 16S rRNA sequencing, Environmental remodeling Copyright © Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits...
Diversity and Evolution of Computationally Predicted T Cell Epitopes Against Human Respiratory Syncytial Virus
Publication Date 1-1-2023 Journal PLOS Computational Biology DOI 10.1371/journal.pcbi.1010360 PubMedCentral® Posted Date 1-10-2023 PubMedCentral® Full Text Version Post-print Published Open-Access yes Keywords Humans, Respiratory Syncytial Virus, Human, Epitopes, T-Lymphocyte, Viral Fusion Proteins, Respiratory Syncytial Virus Infections, Antibodies, Viral Abstract Human respiratory syncytial virus (RSV) is a major cause of lower respiratory infection.
Female budgerigars prefer males with foraging skills that differ from their own
Abstract Foraging skills influence food intake and may therefore also play a role in mate choice decision. Previous empirical work has shown that individuals benefit from being in groups that include individuals with a variety of foraging skills as this increases foraging success. This idea, formalized in the skill-pool hypothesis, may extend to mate choice.
Peri‐ictal yawning: A potential lateralizing sign in temporal lobe epilepsy
Peri-ictal yawning was an infrequent phenomenon in temporal lobe epilepsy (TLE). It was more commonly observed in patients with non-dominant TLE rather than those with dominant TLE. PY was predominantly associated with the late ictal and postictal phases. It may serve as one of the uncommon vegetative signs in patients with TLE, potentially indicating lateralization to the non-dominant hemisphere.
Correlation between Lund-Mackay computed tomography score and subjective symptoms in Chinese patients with nasal polyps
Abstract Background The association between objective imaging findings and subjective symptoms remains undefined. Aims To investigate the correlation between objective imaging findings and symptom severity in the overall chronic rhinosinusitis with nasal polyps (CRSwNP) population as well as its subendotypes according to the eosinophilic inflammation. Methods Patients with CRSwNP undergoing endoscopic sinus surgery were included.
Neutrophils in nasal polyps exhibit transcriptional adaptation and proinflammatory role depend on local polyp milieu
ResearchInflammation Open Access | 10.1172/jci.insight.184739 JCI Insight. https://doi.org/10.1172/jci.insight.184739. Copyright © 2024, Zhang et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Association Between Preoperative Nasal Mucus Thymic Stromal Lymphopoietin and Decreased Quality of Life in Chronic Rhinosinusitis With Nasal Polyps
• , , , , and , “ Role of IL-25, IL-33, and TSLP in Triggering United Airway Diseases Toward Type 2 Inflammation ,” Allergy , no. ( ): – . • , , , et al., “ Epithelial Activators of Type 2 Inflammation: Elevation of Thymic Stromal Lymphopoietin, but Not IL-25 or IL-33, in Chronic Rhinosinusitis With Nasal Polyps in Chicago, Illinois ,” Allergy , no. ( ): – . • , , , et al., “ Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma ,” New England Journal of Medicine , no. ( ): – .
Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
eLife assessment The paper presents valuable insights into the success of the parasitoid Trichopria drosophilae on Drosophila suzukii, elucidating the importance of both molecular adaptations, such as specialized venom proteins and unique cell types, ecological strategies, including tolerance of intraspecific competition and avoidance of interspecific competition.
Sensing Based on Plasmon-Induced Transparency in H-Shaped Graphene-Based Metamaterials
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Novel and extendable genotyping system for human respiratory syncytial virus based on whole-genome sequence analysis
BACKGROUND: Human respiratory syncytial virus (RSV) is one of the leading causes of respiratory infections, especially in infants and young children. Previous RSV sequencing studies have primarily focused on partial sequencing of G gene (200-300 nucleotides) for genotype characterization or diagnostics. However, the genotype assignment with G gene has not recapitulated the phylogenetic signal of other genes, and there is no consensus on RSV genotype definition.
Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
Abstract The success of an organism depends on the molecular and ecological adaptations that promote its beneficial fitness. Parasitoids are valuable biocontrol agents for successfully managing agricultural pests, and they have evolved diversified strategies to adapt to both the physiological condition of hosts and the competition of other parasitoids.
Communication between the stem cell niche and an adjacent differentiation niche through miRNA and EGFR signaling orchestrates exit from the stem cell state in the Drosophila ovary
Fig 6. Notch signaling acts as a connection between EFGR activity in Cap cells and dpp transcripts in ECs. (A–D’) Germaria from wild-type females (A–A’), miR-124[6] (B–B’), miR-124[6]; bab1 > UAS-EGFR RNAi (C–C’), and bab1 > UAS-EGFR (D–D’) were immunostained for Dl (the ligand of Notch signaling).
Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
Abstract Survival success relies on appropriate ecological strategies and functional traits that realize beneficial fitness. It is widely believed that functional adaptation should cooperate with ecological adaptation, but the lack of empirical evidence limits us better understanding how this adaptation coordination arose and evolves.
Changes in Population Exposure to Rainstorm Waterlogging for Different Return Periods in the Xiong’an New Area, China
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Mechanisms of T Cell Subsets in Sepsis Pathogenesis
Back to Journals » ImmunoTargets and Therapy » Volume 13 Authors Jiang C, Chen J, Sun T , Xu J, Zhu H, Chen J Received 7 November 2023 Accepted for publication 17 January 2024 Published 1 February 2024 Volume 2024:13 Pages 29—44 DOI https://doi.org/10.2147/ITT.S448691 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Michael Shurin Chunhui Jiang,1– 3 Jiani Chen,1– 3 Tong Sun,2,3 Jiaqin Xu,2,3 Hongguo Zhu,2,3...
Transition between distribution patterns in human dynamics with high activity
Complex interactions among a large number of individuals lead to multiple patterns of collective human behavior. However, the theoretical prediction of pattern transitions has not been empirically confirmed. This is because in previous empirical studies, different patterns were observed in different systems, and the coexistence of multiple patterns in the same system was rarely found.
Difference in Quality and Volatile Flavor Compounds of Zingiber officinale Roscoe with Different Drying Methods
In order to study the effect of different drying methods on the quality of ginger (Zingiber officinale Roscoe) in Guizhou Province, the study comparatively analyzed the edible quality, functional components, and volatile flavor compounds of dried ginger. The results revealed that vacuum freeze-drying (VFD) was superior to vacuum microwave drying (WAD), hot air drying (HAD), and natural drying (ND) in terms of retaining ginger color change, rehydration rate, flavonoids, and ginger spicy element.
Palladium-Catalyzed Decarbonylative Annulation of 2-Arylbenzoic Acids with Internal Alkynes toward Phenanthrenes
A palladium-catalyzed decarbonylative annulation of 2-arylbenzoic acids with internal alkynes via C(sp2)–H activation has been developed. A series of phenanthrenes were produced in moderate to good yield with good functional group tolerance. The mechanism study indicated that the C(sp2)–H activation should be the rate-determining step during the reaction.
Diversity and evolution of computationally predicted T cell epitopes against human respiratory syncytial virus
Lineage specific T cell epitope profiles We then extended T cell epitope predictions from RSV representative strains to multiple wild-circulating strains. The distribution and diversity of T cell epitopes across different strains are illustrated in heatmaps with the corresponding time-scaled phylogenies (S1 and S2 Figs).
A Decade of CRISPR-Cas Gnome Editing in C. elegans
Abstract : CRISPR-Cas allows us to introduce desired genome editing, including mutations, epitopes, and deletions, with unprecedented efficiency. The development of CRISPR-Cas has progressed to such an extent that it is now applicable in various fields, with the help of model organisms. C. elegans is one of the pioneering animals in which numerous CRISPR-Cas strategies have been rapidly established over the past decade.
A synergistic architecture design on integrally boosting the hydroxyl adsorption and charge transfer for oxygen evolution reaction
A synergistic architecture design on integrally boosting the hydroxyl adsorption and charge transfer for oxygen evolution reaction Jiani Chen, Shiliang Zhu, Lei Ge, Sixuan She, Dongliang Liu, Yuchen Sha, Wei Zhou and Zongping Shao Abstract The adsorption of surface reactant hydroxyl and subsequent charge transfer are the cornerstones of alkaline oxygen evolution reaction (OER).
Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes - Nature Microbiology
Abstract Chemical insecticides have been the primary method of mosquito control, but in recent years, mosquitoes have become resistant to these compounds. Metarhizium fungi are emerging as promising alternatives and can kill mosquitoes with a small number of spores. It was previously shown that caterpillars affected by fungal infections can attract mosquitoes. However, the mechanisms and potential applications of this attraction are lacking.
Hypermutated tumours across 11 cancer types show three distinct immune subtypes
Highlights • HM tumours fell into three distinct immune subtypes: HM1, HM2 and HM3. • HM3 tumours were correlated with CD8 T cell infiltration and prolonged survival. • HM2 tumours were correlated with stromal infiltration, EMT and poor outcome. Abstract Background Complete remission is observed in less than half of hypermutated (HM) tumours after immune checkpoint blockade therapy, indicating that HM tumours are very heterogeneous.
Chronic post-encephalitic epilepsy following Japanese encephalitis: clinical features, neuroimaging data, and outcomes
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig.
Epilepsy in China: Factors influencing Marriage Status and fertility
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig. 1 a) Comparison marriage rate of PWE and national Chinese population. b) Proportion of PWE with the first onset of seizure before marriage and after marriage. c) Comparison marriage rate of male PWE and national male Chinese. d) Comparison marriage rate of female PWE and national female Chinese. *p < 0.05. **p < 0.005. Fig.
Factors associated with seizure-related motor vehicle accidents among patients with epilepsy in West China
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Problem-solving males become more attractive to female budgerigars
Who's a clever boy then? There is considerable value in choosing a smart mate. The suggestion that mate choice has thus shaped the evolution of cognition has been around since Darwin's time, but testing this hypothesis is difficult. Chen et al. found that female budgerigars shifted their preference to previously nonpreferred males after these males demonstrated the ability to solve a problem that stumped the originally preferred males (see the Perspective by Striedter).
Green Algae as Carriers Enhance the Bioavailability of 14C-Labeled Few-Layer Graphene to Freshwater Snails
The waterborne exposure of graphene to ecological receptors has received much attention; however, little is known about the contribution of food to the bioaccumulation potential of graphene. We investigated the effect of algal food on the uptake and distribution of 14C-labeled few-layer graphene (FLG) in freshwater snails, a favorite food for Asian people. In a water-only system, FLG (?158 ?g/L) was ingested by and accumulated in the snails.
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