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Laurel Thomas

As seen in: Nature, Sunday Mirror, The Daily Mirror, Michigan News, Phys.org, Medical Xpress, Cell Press, AlterNet, Nextgov/FCW, Tech Xplore and
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Articles

PACS1 syndrome mutation disrupts dynein-mediated cargo transport via HDAC6 and BICD2

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By Yunhan Yang, Laurel Thomas, Kun Chen, You-Jin Choi, Kenneth D. Greis, Gary Thomas, Sabrina Villar-Pazos, Wendy D. Haffey, Andrew D’Agostino, Kayleigh Fanelli, Vihaan Rathi, Maanas S. Matlapudi
| Nature Verified
Abstract PACS1 syndrome is a neurodevelopmental disorder caused by a recurrent heterozygous missense mutation in PACS1 (p.R203W). We previously showed that PACS1R203W aberrantly potentiates HDAC6 activity, leading to Golgi fragmentation and neuronal deficits through an unresolved mechanism (Villar-Pazos and Thomas et al., Nature Commun. 14:6547-6564 (2023)).
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By Laurel Thomas
| The University Record
They were supposed to transform learning at the university — 128 projects that received a share of $25 million to develop innovative, multidisciplinary teaching and learning projects. Now, more than 10 years since the Third Century Initiative was announced, a look at a handful of the well-funded projects shows most have achieved what they set out to do and then some. The goal of the initiative was to define teaching and learning for the university’s next century that began in 2017.
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First-year law students tout value of early clinic experience

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By Laurel Thomas
| University of Michigan
The University of Michigan Law School is well known for the headline-making, hands-on work that students, with guidance from faculty, do to gain freedom for wrongfully convicted individuals across the country. Although not as well publicized, there also is a group of students each year that provide many hours of free legal assistance to people closer to the university’s home.
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