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Articles by Luyao Wang
Computer Science > Robotics
Embodied agents must translate multimodal observations and user requests into executable actions while adapting to product constraints, changing goals, and execution feedback. We present JoyInside-VLM-Agent, a ReAct-style multimodal agent developed through product-conditioned trajectory construction and staged policy learning for robotic platforms and smart hardware.
Correction: Case Report: Lymphatic malformation in a paediatric patient with a 7-year follow-up
A Correction on Case Report: Lymphatic malformation in a paediatric patient with a 7-year follow-up By Wang L and Guo L (2026). Front. Pediatr 14:1836317. doi: 10.3389/fped.2026.1836317 Author affiliation Adding: Affiliation Department of Vascular anomalies and Interventional Radiology, Jinan Children's Hospital, Jinan, China was omitted from the paper. This affiliation has now been added for author(s) Luyao Wang and Lei Guo.
The nose–brain axis as a neuroimmune conduit: how allergic rhinitis rewires the central nervous system
Abstract Allergic rhinitis (AR) has traditionally been regarded as a type I hypersensitivity disorder confined to the nasal mucosa. However, persistent symptoms, nasal hyperresponsiveness, and comorbid neuropsychiatric disturbances—including headache, fatigue, cognitive impairment (“brain fog”), anxiety, and depression—cannot be fully explained by peripheral inflammation alone, thereby implicating the involvement of central sensitization.
Efficacy and safety of modified Xiaoyao-san in the treatment of postoperative depression of breast cancer: a systematic review and meta-analysis
Abstract Objective: To comprehensively evaluate the efficacy and safety of modified Xiaoyao-san (XYS) in the treatment of postoperative depression of breast cancer patients through systematic review and meta-analysis. Methods: Randomized controlled trials (RCTs) on the treatment of postoperative depression of breast cancer patients with modified XYS were searched from eight databases. All relevant literature from the inception of each database up to 12 July 2026 were retrieved.
Re-instrumenting quality function deployment for generative engineering design: a small language model-based adaptive QFD framework
Abstract While traditional Quality Function Deployment (QFD) remains effective at translating stakeholder requirements into engineering characteristics, its static formulation is poorly suited to contemporary generative design, where rapid synthesis can bypass requirement traceability and constraint governance.
OAM-Based Multiplexed Communication System With a Reflective Metasurface
1 Introduction In the context of the rapid advancement of emerging technologies such as the Internet of Things and artificial intelligence, global data traffic is experiencing exponential growth, thereby generating an escalating demand for wireless communication capacity [1-3]. Traditional wireless systems encounter constraints in both spectrum resources and transmission rates, which impede their capability to fulfill the increasing data requirements [4].
An epigenetic switch in β -cells links mitochondrial stress to inflammatory fate via HMGB1 acetylation
Summary Pancreatic β-cell failure in diabetes is driven by chronic inflammation, yet how metabolic stress determines pro-inflammatory cell fate remains unclear. Here, we report that sublethal oxidative stress activates a β-cell-enriched epigenetic switch that licenses intrinsic inflammation. We identify a β-cell-enriched vulnerability wherein oxidative stress disrupts mitochondrial NAD⁺/acetyl-CoA flux, skewing the nuclear equilibrium between the deacetylase SIRT1 and acetyltransferases p300/CBP.
Microbiological characteristics of granulomatous lobular mastitis revealed by metagenomic sequencing
YD, JL and LW contributed equally. Handling editor Vikram Deshpande. Contributors YD and XP designed the study together; YD analysed the data, wrote and revised the first draft of the manuscript; JL and LW collected literature and clinical features of patients; QZ, CX, AP, RC, CL, BL and JP collected tissue samples; XP approved the submission of the final version of this manuscript. All authors agreed with the publication of this manuscript. XP is the guarantor of this study.
Transcriptomic analysis of tissue-resident memory T cells of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention
Abstract The fallopian tube (FT) is increasingly recognized as the origin of high-grade serous ovarian cancer (HGSOC), yet its immune landscape remains poorly understood. Here, we employ single-cell RNA sequencing and paired T-cell receptor sequencing to profile tissue-resident memory-like T cells (TRML) from patient-derived matched non-cancerous FT, metastatic tumors, and peripheral blood.
Impact of delivery mode on diastasis recti abdominis, pelvic floor muscle function, and quality of life in early postpartum women: a cross-sectional study
Abstract Background: The early postpartum period is critical for maternal recovery. This study aimed to investigate the impact of delivery mode on diastasis recti abdominis (DRA), pelvic floor muscle strength, sleep quality, and overall quality of life at 6–8 weeks postpartum. Methods: A cross-sectional study was conducted among 196 primiparous postpartum women, including 100 vaginal deliveries and 96 caesarean sections.
A Tissue-Homologous Keratin-PBA Hydrogel Integrating Rationally Designed Nanomicelles Enables Microenvironment-Adaptive Repair of Chronic Diabetic Wounds
1 Introduction Chronic diabetic wounds represent one of the most challenging complications of diabetes mellitus [1], profoundly impairing the quality of life of over 589 million adults living with diabetes worldwide in 2024 [2], leading to considerable healthcare and economic pressures for society, particularly in China, which currently has the largest diabetic population [3].
New tool tracks RNA modification dynamics in single cells
If DNA is the master instruction manual inside a human cell, RNA can be thought of as a working copy that helps cells use genetic information to produce proteins and carry out essential processes. RNA can acquire chemical modifications as it is produced and processed. These modifications act like small marks on the working copy: they do not change the underlying DNA instructions, but they can influence how RNA is processed, used, and how long it remains stable within a cell.
Surface immune signaling unlocks NLR activation through mRNA alternative splicing
Editor’s summary Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Plants use cell surface receptors to detect conserved microbial features and intracellular immune receptors to identify pathogen proteins secreted into the host. Gao et al.
Contraction, recombination and innovation shape the dynamic pan-plastome of Astragalus sinicus
Abstract Astragalus sinicus (Chinese milkvetch) is a legume crop of major economic and ecological importance, regularly employed in sustainable farming to enhance soil nitrogen. Despite its significance, plastome structural dynamics within the Inverted Repeat-Lacking Clade (IRLC) of Fabaceae remain poorly understood, and pan-plastome resources for this species are lacking. Here, we present a pan-plastome for A. sinicus using 140 resequenced individuals.
Biomass-based thermally tunable dual afterglow with room temperature daylight visibility
Abstract Biomass-derived long-persistent afterglow materials that simultaneously deliver thermally activated delayed fluorescence (TADF) and room-temperature phosphorescence (RTP) are highly sought after but remain challenging to achieve, particularly when daylight-visible RTP and high-temperature-tolerant, color-tunable TADF are required.
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
1 Introduction Seed vigor, defined by the International Seed Testing Association (ISTA) as a core trait representing the sum of performance factors that determine acceptable seed germination activity and performance under diverse environmental conditions, offers significant advantages in describing germination rate, emergence rate, resistance to abiotic and biotic stresses, and storage capacity under varying conditions [1, 2].
Omnidirectional ionic locking network for stable perovskite photovoltaics
Abstract The efficiency–stability trade-off in perovskite solar cells continues to be challenged by issues such as ion migration and defects at grain boundaries and interfaces. Here we address this challenge by an in situ kinetic processing route using a bifunctional spacer, 2-(prop-2-en-1-ylsulfanyl)ethan-1-amine hydrochloride (PYA).
Case Report: Lymphatic malformation in a paediatric patient with a 7-year follow-Up
Abstract Lymphatic malformations (LMs) are common low-flow vascular anomalies in children. Macrocystic LMs are particularly prone to haemorrhage and may result in life-threatening airway compression. This report describes a 2-month-old female infant with a mixed lymphatic malformation involving the maxillofacial and cervical regions complicated by acute intracystic haemorrhage and severe dyspnoea.
Study on the driving mechanisms of land use change on water yield and carbon storage based on the InVEST-PLUS-GeoDetector model
Abstract Under the dual pressures of global climate change and intensive human activities, the degradation of ecosystem services has become a critical challenge for regional sustainable development. This study aims to investigate the spatiotemporal evolution and driving mechanisms of water yield and carbon storage in the middle reaches of the Yellow River.
An entropy-regulating molecular lock stabilizes formamidinium lead halide perovskite
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Editor’s summary Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary A molecular additive stabilizes the photoactive phase of formamidinium lead iodide (FAPbI3) by increasing FA+ cation rotational entropy and suppressing the disordering of [PbI6]4− octahedra. Miao et al.
By Zhipeng Lin, Hanshen Tsai, Hinano Takase, Tianyin Miao, Sanwan Liu, Xia Lei, Yong Zhang, Wenpei Li, Qisen Zhou, Jianan Wang, Nikita A. Emelianov, Victoria V. Ozerova, Wenqiang Wang, Zheng Zhou, Zhongjie Zhu, Lanlu Lu, Zhenhua Chen, Jingyuan Ma, Erxiang Xu, Luyao Wang, Yunfei Li, Zhengtian Tan, Shijie C Zheng, Guilin Liu, Valeria S. Bolshakova
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Science Magazine
Verified
Mitofusin-Decorated Extracellular Vesicles Enable Targeted Nucleic Acid Delivery to Mitochondria Click to copy article link Article link copied!
Cite Jump to ExpandCollapse LetterMay 11, 2026 Mitofusin-Decorated Extracellular Vesicles Enable Targeted Nucleic Acid Delivery to Mitochondria Click to copy article linkArticle link copied! Jiafeng Zhong Jiafeng Zhong Fudan University, Shanghai 200433, China School of Medicine, Westlake University, Hangzhou, Zhejiang 310023, China Luyao Wang* Luyao Wang Department of Materials Science and Engineering, Westlake University, Hangzhou, Zhejiang 310030, China *Email: [email protected] Wenjing...
Osteoblastic sclerostin loop3-LRP4 interaction required by sclerostin to inhibit bone formation
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Abstract Sclerostin negatively regulates bone formation. The marketed antibody against sclerostin loop2 promoted bone formation but may have caused severe cardiovascular events in clinical use. In our published studies, sclerostin loop3 was found to be involved in inhibitory effects of sclerostin on bone formation, whereas cardiovascular protective effects of sclerostin in mice were independent of loop3.
By Luyao Wang, Xiaohui Tao, Shijian Ding, Ning Zhang, Xin Yang, Shenghang Wang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Hua Yue, Péter Ferdinandy, Tao Zhang, Shu Zhang, Zhenlin Zhang, Aiping Lu, Baoting Zhang, Ge Zhang, Hewen Jiang, Heiwa So, Xianghang Luo
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Nature
Verified
A Combinatorial Strategy of Semirational Screening and Rational Design for Engineering an α-1,2-Fucosyltransferase toward Efficient 2′-Fucosyllactose Biosynthesis Click to copy article link Article link copied!
Biotechnology and Biological TransformationsApril 15, 2026 Luyao Wang Key Laboratory of Industrial Biotechnology Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China State Key Laboratory of Food Science and Resources, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China Zenglin Zhang Key Laboratory of Industrial Biotechnology Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi,...
Lithium ion ‘fast track’ could increase battery safety, lifespan
Recently, Professor Li Yang and her team from Xi’an Jiaotong-Liverpool University, together with researchers from the University of Liverpool, published a study offering a new approach to improving the safety, lifespan and stability of lithium-metal batteries. The research, published in the journal Advanced Functional Materials, proposes a new strategy to regulate lithium ion transportation using porosity and acidity in molecular sieves.
Retraction Note: A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer
Retraction to: Nature Communications https://doi.org/10.1038/s41467-017-01565-6, published online 09 Novmber 2017 The Editors have retracted this article. After publication, concerns were raised regarding some of the data presented in Figs. 7 and 8, specifically: • Fig. 7c CRO and NucA images appear to overlap. • Fig. 7d PTX and NucA-PTX images appear to overlap. • Fig. 8d Heart CRO and NucA-PTX images appear to overlap. • Fig. 8d Liver PTX and NucA images appear to overlap. • Fig.
3D-printable phosphorescent woody materials
Abstract The preparation of sustainable biophosphors exhibiting room-temperature phosphorescence (RTP) for additive manufacturing presents both significant scientific promise and substantial synthetic challenges. To address this technological gap, with this research, we engineer CX-Wood using rational molecular design by grafting carboxyl-functional groups onto native lignocellulosic matrices, enabling direct ink writing (DIW) using our RTP wood composite.
ZmWRKY29 Transcriptionally Represses ZmRBOHC to Attenuate ROS Production and Facilitates Gibberella Stalk Rot Susceptibility in Maize
1 Introduction Stalk rot, a devastating stalk disease in maize (Zea mays L.), primarily occurs during the tasselling-silking phase of the reproductive stage (Kazan and Gardiner 2018). The infected maize plants display severely compromised water and nutrient uptake, elevated lodging susceptibility and ultimately result in substantial yield loss (Jackson et al. 2009).
Photoswitchable isomers to improve grain boundary resilience and perovskite solar cells stability under light cycling - Nature Energy
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Abstract Realizing stable and scalable perovskite solar cells (PSCs) under real-world outdoor conditions remains a challenge for deployment.
By Zuhong Zhang, RUI ZHU, Guixiang Li, Ying Tang, Hongzhuo Wu, Jinbo Zhao, Jiaxin Wu, Thomas Gries, Artem Musiienko, Shengnan Zuo, Zhe Li, Bingchen He, Zhenhuang Su, Xingyu Gao, Weiwei Zuo, Bo Hou, Jorge Pascual, Luca Scalaa Sapienza, Luyao Wang, Lin-Long Deng, Yu Jia, Paul Dyson, Mohammad Khaja Nazeeruddin, Michael Saliba, Antonio Abate
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Nature
Verified
Multi-zonal anaerobic ammonium oxidation for mainstream municipal wastewater treatment - Nature Sustainability
Abstract Biological nitrogen removal is a main contributor to the carbon footprint of municipal wastewater treatment plants (MWWTPs). Anaerobic ammonium oxidation (anammox) is key to decarbonizing MWWTPs. However, anammox technology has long been developed following the ‘hotspot’ concept, which spatially confines anammox to specific zones in MWWTPs, leaving its potential underexploited in mainstream treatment.
High-Level De Novo Biosynthesis of Difucosyllactose in Escherichia coli through Application and Engineering of a Novel α-1,3-Fucosyltransferase
Cite Jump to ExpandCollapse Biotechnology and Biological TransformationsJanuary 26, 2026 High-Level De Novo Biosynthesis of Difucosyllactose in Escherichia coli through Application and Engineering of a Novel α-1,3-Fucosyltransferase Click to copy article linkArticle link copied! Zenglin Zhang Zenglin Zhang Key Laboratory of Industrial Biotechnology Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China State Key Laboratory of Food...
Task demand modulates somatosensory-frontoparietal networks during delay and retrieval periods in tactile working memory - Communications Biology
Abstract The primary somatosensory cortex (SI) is traditionally regarded as a sensory encoding region, yet growing evidence implicates it may also work in the maintenance and manipulation of tactile working memory (TWM), and interact with frontoparietal (FP) pathway under varying task demands. Here, we use high-field fMRI and a custom pneumatic tactile stimulation device to examine neural dynamics across distinct WM phases during a retro-cue task.
Author Correction: Stabilizing high-efficiency perovskite solar cells via strategic interfacial contact engineering - Nature Photonics
Correction to: Nature Photonics https://doi.org/10.1038/s41566-025-01791-1, published online 7 November 2025. In the version of the article initially published, Lennart Frohloff and Norbert Koch (both Department of Physics, Humboldt University of Berlin, Berlin, Germany) were missing from the author list and have now been added to the HTML and PDF versions of the article.
Adipocytic sclerostin loop3-LRP4 interaction required by sclerostin to impair whole-body lipid and glucose metabolism - Nature Communications
Abstract Sclerostin, which has three loops, inhibits bone formation and impairs whole-body lipid and glucose metabolism. The marketed therapeutic sclerostin antibody for postmenopausal osteoporosis (POP) mainly targeting loop2 promotes bone formation and improves whole-body lipid and glucose metabolism. However, FDA/EMA warns of its cardiovascular risk.
Materials science joins ESI Global Top 1%
According to the latest Essential Science Indicators (ESI) update on 8 January 2026, Xi'an Jiaotong-Liverpool University's (XJTLU) research in the field of materials science has entered the ESI Global Top 1% for the first time. This marks the second major milestone for XJTLU's research impact in a short period. In November 2025, the University's research in chemistry was also included in the ESI Global Top 1%.
Materials science joins ESI Global Top 1%
According to the latest Essential Science Indicators (ESI) update on 8 January 2026, Xi’an Jiaotong-Liverpool University’s (XJTLU) research in the field of materials science has entered the ESI Global Top 1% for the first time. This marks the second major milestone for XJTLU’s research impact in a short period. In November 2025, the University’s research in chemistry was also included in the ESI Global Top 1%.
Environmental conferences' formats should reflect values
Researchers often travel long distances to attend international scientific conferences, generating carbon emissions over just a few days that may outweigh the benefits of many environmental efforts. During the Covid-19 pandemic, the practice of holding these conferences online significantly reduced travel-related emissions.
Upregulated Calcium Sensing Receptor Mediates Pulmonary Venous Remodeling in Pulmonary Hypertension
Disclosure The authors have nothing to report. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description apha70142-sup-0001-Supinfo.docxWord 2007 document , 33.3 MB Table S1: Lung cancer patients demographics.
Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial
Back to Journals » Therapeutics and Clinical Risk Management » Volume 22 Authors Wang L, Zhou J, Liu Q , Qian K, Wang L, Xie C Received 11 December 2025 Accepted for publication 22 April 2026 Published 7 May 2026 Volume 2026:22 588126 DOI https://doi.org/10.2147/TCRM.S588126 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor De Yun Wang Luyao Wang, Jie Zhou, Qian Liu, Kun Qian, Lei Wang, Chenglan Xie Department...
C2C12‐Derived ApoVs Promote Skeletal Muscle Development and Ameliorate Age‐Related Muscle Loss Through Igf1r/PI3K/AKT/mTOR Pathway
1 Introduction As the largest organ in the body, skeletal muscle occupies over 40% of body weight [1]. It is not only responsible for body movement but also plays important roles in metabolic regulation and temperature maintenance [2]. The disorders of skeletal muscle development are closely associated with aging, type 2 diabetes, cancer and muscle-related diseases, such as amyotrophic lateral sclerosis (ALS) and Duchenne muscular dystrophy (DMD) [3-5].
Researchers uncover rare form of iron inside carbon nanotubes
New research from Xi’an Jiaotong-Liverpool University (XJTLU) could help scientists design next-generation magnetic, spintronic (spin transport electronics), and quantum materials. The work, led by Dr Filippo Boi of the Department of Chemistry and Materials Science, revealed an unusual atomic arrangement of iron (crystal structure, or phase) when confined inside carbon nanotubes. This type of iron phase would be unstable in ambient (normal room temperature and air pressure) conditions.
Researchers uncover rare form of iron inside carbon nanotubes
New research from Xi'an Jiaotong-Liverpool University (XJTLU) could help scientists design next-generation magnetic, spintronic (spin transport electronics), and quantum materials. The work, led by Dr Filippo Boi of the Department of Chemistry and Materials Science, revealed an unusual atomic arrangement of iron (crystal structure, or phase) when confined inside carbon nanotubes. This type of iron phase would be unstable in ambient (normal room temperature and air pressure) conditions.
Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action
1 Introduction Sclerostin, which negatively regulates bone formation, is a novel target for bone anabolic therapy.[1] Structurally, sclerostin contains three central loops (loop1, loop2, and loop3), with loop2 being the primary target of the marketed therapeutic antibody for treatment of postmenopausal osteoporosis.[2] However, clinical trials (BRIDGE and ARCH) revealed severe cardiovascular risks, including myocardial infarction and stroke.[3-9] The US Food and Drug Administration (US-FDA)...
Xi’an Jiaotong-Liverpool University this year achieved its highest-ever medal tally at the International Genetically Engineered Machine (iGEM) competition, the world’s most influential synthetic biology event for students. Four undergraduate teams from XJTLU won two gold medals and two silvers, with one team ranking in the top 10 worldwide. Three teams were also nominated for Best Project in their respective tracks.
Stabilizing high-efficiency perovskite solar cells via strategic interfacial contact engineering - Nature Photonics
Abstract Surface passivation in perovskite solar cells can enhance device efficiency, yet incomplete interfacial functionality poses challenges to long-term reliability. Here we present a strategic interfacial engineering approach using sodium heptafluorobutyrate to fully functionalize the perovskite surface.
Integrated treatment utilizing both Chinese and Western medicine for refractory diabetic foot ulcers: a case report
Introduction According to the International Diabetes Federation (IDF) Diabetes Atlas, approximately 500 million adults globally currently suffer from diabetes mellitus (DM), and this number is expected to increase by 46% by 2045 (1). Diabetic foot ulcers (DFUs) are one of the most severe complications of DM, affecting 6.3% of patients (2), and a DM patient undergoes an amputation due to DFU every 20 seconds (3).
Reversible Thermal Tuning of High‐Q Non‐Local Lithium Niobate Metasurfaces
1 Introduction Optical metasurfaces, a versatile platform for wavefront manipulation, have been extensively explored in recent years owing to their potential for enabling compact, multifunctional photonic devices across a wide range of applications.[1-3] However, as application demands grow, particularly the need to integrate multiple functions into a single element, conventional static metasurfaces with fixed functionalities after fabrication are increasingly insufficient to meet evolving...
Defect‐Healing in Perovskite Photovoltaics Driving Long‐Term Reliability and Performance
Conflict of Interest The authors declare no conflict of interest. References 1, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , et al., Sci. China Chem. 2022, 65, 2369. 2, , , , , , , , , , , , , Joule 2024, 8, 1691. 3, , , , , , , , , , , , Nat. Commun. 2024, 15, 10908. 4, , , , , , , , , , , , , Energy Environ. Sci. 2024, 17, 5080. 5, , , , , , , , , , , , , , , , , Energy Environ. Sci. 2025, 18, 7082. 6, , , , , , , , , , , , , , , , , , Adv. Mater. 2019, 31, 1903559.
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