Ming Sun
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Articles by Ming Sun
Astrophysics > Astrophysics of Galaxies
We present a deep Chandra (130 ks) study of a striking, tidally induced cold front in a subcluster merging with the galaxy cluster MCXC J0157.4-0550. The subcluster, nicknamed the `snail' (J0157), displays an extensive spiral structure that extends to $\sim 260$ kpc --- one of the largest spiral cold fronts identified to date.
SCRMP-mediated SUMOylation of CSNK2B facilitates DNA damage repair to promote cisplatin resistance in small cell lung cancer
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Small cell lung cancer (SCLC) represents the most lethal subtype of lung carcinoma. Platinum-based agents, such as cisplatin and carboplatin, remain the cornerstone of first-line therapy for patients with SCLC, whether administered as chemotherapy alone or in combination with immunotherapy.
TRIM46 drives lung adenocarcinoma progression by stabilizing PRDX1 via SUMOylation
Abstract Lung adenocarcinoma (LUAD) is one of the major subtypes of non-small cell lung cancer (NSCLC), but the molecular mechanisms underlying LUAD initiation and progression remain incompletely understood. In the present study, we identified TRIM46 as a key driver of LUAD progression. TRIM46 is significantly overexpressed in LUAD tissues, and its high expression correlates with advanced disease and poor patient prognosis.
The origin and domestication of modern cultivated Chrysanthemum × morifolium
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Abstract The modern cultivated chrysanthemum (Chrysanthemum × morifolium Ramat.) is a globally important ornamental plant, ranking as the second-largest cut flower after roses. Here, to unravel its complex origin and domestication history, we achieved 6 haplotypes of the elite hexaploidy cut chrysanthemum cultivar ‘Jinba’ (2n = 6x = 54). By constructing a genome-wide variant map across 147 core accessions, we classified current Chrysanthemum varieties into 4 wild and 4 cultivated groups.
By Cunquan Yuan, Rui Zhang, Tianci Cong, Yalin Liu, Tingting Sun, Chunhua Li, Ming Sun, Qingqing Yang, Yujie Yang, Man Zhang, Yicen Yao, Qing Yuan, Xiaojie Song, Shuai Sun, Huitang Pan, Jia En Wang, Tangren Cheng, Tangchun Zheng, He Zhang, Guangyi Fan, Qixiang Zhang, Rouzhi Liu, Huien Zhao, Hetong Liu, Huiye Wu
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Nature
Verified
Large-scale AI-guided liver malignancy diagnosis: multicenter study and a single-arm trial
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Abstract Liver malignancies are frequently evaluated on contrast-enhanced computed tomography (CE-CT), but missed or delayed diagnoses remain a clinically important challenge in high-volume, real-world radiology workflows, highlighting the need for scalable diagnostic safety net approaches.
By Xiaoming Zhang, Xu Han, Xiaoli Yin, Jian Zhou, Kai Cao, Qi Liu, Beilei Cui, Qianqian Zhang, Jianyi Qiao, Ming Sun, Wei Liu, Yuan Z. Gao, Shiling Zhong, Ruobing Bai, Tianan Jiang, Olivier Humbert, Sébastien Ourselin, Ke Yan, Qi Zhang, Yang Hou, Tingbo Liang, Ling Zhang, Yu Shi, Chaoya Zhang, Yingshan Gao, Maria A. Zuluaga
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Nature
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Full-Space Radiation-Reflection-Integrated Metasurface for Independent Quad-Channel Wavefront Manipulation (Laser Photonics Rev. 20(13)/2026)
Related Information Full‐Space Radiation‐Reflection‐Integrated Metasurface for Independent Quad‐Channel Wavefront Manipulation , , , , , , , , , , , Scite uses AI to classify citations by whether they support, contradict, or merely mention the referenced claims.
Single-Encounter Augmented Reality–Guided Localization for Resection of Suspected Early-Stage Lung Cancer : A Randomized Clinical Trial
Single-Encounter Augmented Reality–Guided Localization for Resection of Suspected Early-Stage Lung Cancer: A Randomized Clinical Trial Key Points Question Is single-encounter, augmented reality (AR)–guided percutaneous localization noninferior to multiple-encounter computed tomography (CT)–guided localization for achieving successful sublobar resection of CT-detected pulmonary nodules suspicious for early-stage lung cancer?
Case Report: Donor-derived early T-cell precursor acute lymphoblastic leukemia following an allogeneic hematopoietic stem cell transplantation for pediatric severe aplastic anemia
Abstract Donor cell leukemia is a rare but severe complication following an allogeneic hematopoietic stem cell transplantation (allo-HSCT), particularly in patients with non-malignant diseases, due to its aggressive clinical progression and poor prognosis. In recent years, with the increasing number of umbilical cord blood stem cell transplantation cases, umbilical cord blood–derived donor cell leukemia has garnered growing attention.
Solving the cooling flow problem with combined jet-wind AGN feedback
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Active galactic nucleus (AGN) feedback is widely viewed as the most promising solution to the long-standing cooling flow problem in galaxy clusters, yet previous models prescribe jet properties inconsistent with accretion physics.
Early life stage fish community structure and environmental drivers in offshore waters of Liaoning Province, Yellow Sea
Abstract Early life stages of marine fishes play a critical role in shaping recruitment variability and population dynamics, yet the environmental processes structuring ichthyoplankton communities remain poorly understood in many marginal seas.
Integrating dietary patterns and metabolomics with machine learning for metabolic syndrome risk assessment in a rural population
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Abstract This study aimed to identify dietary patterns and metabolomic signatures associated with metabolic syndrome (MetS) and develop machine learning models integrating both dietary and metabolomic data for risk assessment. In this cross-sectional study of 2810 adults, four dietary patterns derived using principal component analysis were associated with MetS. Serum metabolomic profiling was conducted in 400 participants using liquid chromatography-tandem mass spectrometry.
By Ming Sun, Yixin Zhang, Jiajin Hu, Yang Yu, Yang Liu Verified, Zhaoqing Sun, Liqiang Zheng, Yanan Ma, Deliang Wen
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Nature
Verified
Author Correction: Electrified interfacial oxygen-down water boosts efficient and durable electrolysis
Correction to: Nature Communications https://doi.org/10.1038/s41467-026-70737-0, published online 23 March 2026 In the version of the article initially published, the units in Fig. 2b were “mF cm−2” but should have been “mV dec−1”. The figure has now been corrected in the HTML and PDF versions of the article.
The Functional Amino Acid l -Proline Enhances Lactation Performance by Activating the SNAT2-P4HA2-mTORC1 Axis Click to copy article link Article link copied!
Omics Technologies Applied to Agriculture and FoodMay 13, 2026 Mingyang Sun State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China Quan Li State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education,...
A Digital Twin-Enabled Framework for Sustainable Regeneration of Cold-Region Industrial Heritage: A Case Study of Harbin China
You are already at the latest version The sustainable regeneration of industrial heritage in cold regions is constrained by severe winter climate, seasonal behavioral shifts, and declining spatial vitality. However, existing research has rarely explained how cold-climate conditions influence catalyst effects and regeneration performance in industrial heritage areas. This study proposes a digital twin-enabled framework for the sustainable regeneration of cold-region industrial heritage.
The influence of inorganic components in the Shengli lignite on the bond breaking and functional group evolution patterns during pyrolysis
1 INTRODUCTION Low-rank coal, which constitutes over half of the world's coal reserves, is characterized by a low degree of coalification and a high volatile matter content.[1, 2] The volatile matter content in China's low-rank coal resources alone is estimated to be equivalent to approximately 1000 billion tons of oil and gas resources.[3] By utilizing the pyrolysis technology to extract this portion of oil and gas resources, and further converting them into high-value oil products,...
A novel microprotein L3EMP triggers lung adenocarcinoma progression by catalysing the deubiquitination of SIRT1
Abstract Lung adenocarcinoma (LUAD) has limited therapeutic targets and poor survival. Noncanonical open reading frames (ORFs) in long noncoding RNAs (lncRNAs) may encode functional microproteins, but their roles in LUAD remain unclear. This study aims to characterise the LINC00973-encoded microprotein L3EMP and to investigate its tumour-promoting mechanisms and therapeutic potential.
Advancements in nanomaterials for the treatment and management of vascular surgeries: from drug delivery to biomedical implants
Abstract Vascular surgery is an important procedure that is carried out to treat diseases of the entire vascular system. Intraoperative hemostasis, precise vision of intricate vascular anatomy, restenosis, implant-associated infection, and inadequate endothelium regeneration are among the enduring difficulties that continue to limit vascular surgery.
Electrified interfacial oxygen-down water boosts efficient and durable electrolysis
Abstract The oxygen evolution reaction proceeds through proton-coupled electron transfers, mastering interfacial proton dynamics is therefore the critical nexus for simultaneously achieving high catalytic activity and long-term stability. Herein, we establish an oxygen-down water adlayer (H2O ↓ ) that concurrently optimizing initial water deprotonation and subsequent proton transport.
Addressing Spatiotemporal Data Gaps in Fish Abundance Modelling: Insights From Offshore Wind Impacts in the U.S. Mid‐Atlantic
1 Introduction Fishery-independent surveys are an integral component of fisheries management. They provide critical abundance indices and representative biological information for stock assessments, making them essential for fisheries management. Robust survey data are obtained through statistically rigorous design that is strictly followed over time to ensure spatiotemporal abundance is truthfully reflected.
[2602.07211] Equipping LLM with Directional Multi-Talker Speech Understanding Capabilities
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Full‐Space Radiation‐Reflection‐Integrated Metasurface for Independent Quad‐Channel Wavefront Manipulation
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description lpor70914-sup-0001-SuppMat.pdf2.3 MB Supporting File: lpor70914-sup-0001-SuppMat.pdf.
Ionizable Nano‐PROTAC Overcomes Endosomal Entrapment for Enhanced LRG1 Degradation and Tumor Suppression
Conflict of Interests The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie70499-sup-0001-SuppMat.docx5.5 MB Supporting Information References 1, , , , , , , , , , , , , Nature 2013, 499, 306–311, https://doi.org/10.1038/nature12345. 2, , , , , , , , , , , , , J. Contr.
Phytoremediation of strontium by different sunflower cultivars (Helianthus annuus L.): insights from accumulation traits and subcellular distribution
Abstract Radioactive 90Sr endangers ecosystems and human health owing to its long half-life and high food chain mobility. Phytoremediation is a promising alternative to conventional remediation. This study aimed to screen sunflower (Helianthus annuus L.) varieties with high Sr accumulation and clarify the underlying mechanisms.
Author response: comparative efficacy of HSCT strategies in pediatric aplastic anemia - Bone Marrow Transplantation
TO THE EDITOR: Aplastic anemia (AA) is a severe condition that leads to bone marrow failure in children, marked by a decrease in peripheral blood and bone marrow cells [1, 2]. Children with severe aplastic anemia (SAA) and very severe aplastic anemia (VSAA) experience fast progression of the disease, which greatly affects their long-term well-being, and also have a high risk of fatality.
Combination of vascular surgery with novel vascular targeting agents as cancer therapeutics
1 Introduction The vascular compartment of solid tumors functions not merely as a passive supply route but as a dynamic regulatory network that dictates tumor survival, invasiveness, and metastatic potential (1). Modern oncology has recognized the therapeutic potential of targeting this network, moving beyond classical cytotoxic chemotherapy toward molecularly targeted agents. This paradigm shift includes the development of agents designed to control pathological neovascularization (2).
Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
Keywords arsenic m6A mRNA methylation skin cancer translation Research topic(s) CP: Cancer Introduction Arsenic is a metalloid found both within the Earth’s crust and derived from anthropogenic sources, such as industry waste discharge.1 Arsenic from the Earth’s crust can leach into neighboring bodies of water and lead to contamination.1 A primary source of arsenic exposure is through ingesting contaminated drinking water.
Control of Effective Elastomer Density Enables Mechanically Robust and High‐Efficiency Intrinsically Stretchable Organic Solar Cells
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma70877-sup-0001-SuppMat.docx24.3 MB Supporting Information adma70877-sup-0002-Data.zip1 KB Supporting Data References 1, , , , , , , Nat. Rev. Mater. 2018, 3, 18003. 2, , , , , , , , , , , , , Science 2018, 361, 1094. 3, , , , , , , , , , , Chem. Rev. 2022, 122, 14180. 4, , , , , , , , , Joule 2022, 6, 171. 5, , , , , , , , , , , , , , , , , Adv. Energy Mater. 2025, 15, 2405205.
TRIM31 triggers colorectal carcinogenesis and progression by maintaining YBX1 protein stability through ubiquitination modification - Cell Death & Disease
Abstract Colorectal cancer (CRC) is one of the most common gastrointestinal tumors, and one of the leading causes of cancer-related deaths worldwide. However, the molecular mechanisms underlying CRC development and progression have not been fully elucidated until now. Emerging studies have shown that post-translational modifications of proteins, especially ubiquitination modifications, play an important role in tumorigenesis and progression.
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Comprehensive risk profiling and long-term cardiovascular toxicity in HER2-positive breast cancer patients treated with trastuzumab
Introduction Breast cancer remains the most frequently diagnosed malignancy and a primary cause of cancer-related mortality among women globally (1, 2). The amplification or overexpression of the human epidermal growth factor receptor 2 (HER2) gene, found in approximately 15-20% of breast cancers, defines an aggressive subtype with a historically poor prognosis (3, 4).
Frontiers | Single-cell analysis of microglial activation after traumatic brain injury reveals immune signaling pathways linked to mitochondrial dysfunction and brain aging
ORIGINAL RESEARCH article Volume 17 - 2025 | https://doi.org/10.3389/fnagi.2025.1657523 This article is part of the Research TopicMitochondrial Dysfunction in Cellular and Molecular Mechanisms of Brain AgingView all 3 articles Introduction Traumatic brain injury (TBI) is a complex neurological disorder caused by external mechanical forces, resulting in both immediate neuronal damage and long-term functional impairments.
Interface mechanical behaviors and failure mechanism of bamboo scrimber-UHPC composites: test and modelling
Advanced search Journal of Sustainable Cement-Based Materials Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/21650373.2025.2522872?needAccess=true Abstract The integration of bamboo scrimber with Ultra-High Performance Concrete (UHPC) offers a promising approach to enhancing the mechanical performance of timber-concrete composites while reducing their life-cycle carbon...
Investigation into Noncontact Protective Strategy of Ancient Bridge Foundations against Scour Risk: An Experimental Study
Get full access to this article View all available purchase options and get full access to this article. Data Availability Statement Some or all data, models, or code that support the findings of this study are available from the corresponding author upon reasonable request.
The Early Life Stage Fish Community Structure and Its Relationship with Environmental Factors in the Offshore Waters of the Liaoning Province in the Yellow Sea
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Highly Selective Oxygen Electroreduction to Hydrogen Peroxide on Sulfur‐doped Mesoporous Carbon
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
A reference genome assembly of the alpine forage grass Elymus nutans
Abstract Elymus nutans Griseb. (Poaceae: Triticeae, 2n=6x=42) is a dominant perennial plant species in the Qinghai-Tibetan Plateau in China, which is an important forage resource in high-altitude and cold regions and is the most popular species used for high yield artificial grassland planting because of its rich nutritional value and good palatability for herbivorous ruminant animals. In this study, using advanced sequencing technology, we generated an allohexaploid reference genome for E.
Effect of Solid Solution Treatment Routes on the Microstructure Configuration of a Third-Generation Ni-Based Superalloy
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Integrated Scheduling Algorithm Based on Improved Semi-Numerical Algorithm
1. Introduction Integrated scheduling is applied to the production of treelike structured products with process constraints, and it deals with both the stages of the processing and the assembly. In addition, it involves the activity of allocating limited equipment, personnel and other resources to obtain the best time efficiency and equipment utilization rate, which meets the requirements of the state to vigorously develop process technology to adapt to intelligent manufacturing.
Predicting the spatial demand for public charging stations for EVs using multi-source big data: an example from jinan city, china - Scientific Reports
Abstract Under the pressure of carbon pollution and resource scarcity, electric vehicles (EVs) have gradually replaced fuel vehicles as a new trend of low-carbon transformation. However, public charging stations (PCS) face with problems such as insufficient quantity and unreasonable distribution.
The Resilience Evaluation and Optimization of Primary Healthcare Facilities in Harbin’s Main Urban Area based on Network Analysis
This version is not peer-reviewed. Ming Sun,Bingbing Wang * Ming Sun,Bingbing Wang * This version is not peer-reviewed. Submitted: 23 February 2025 You are already at the latest version The development of primary healthcare facilities facilitates a balanced distribution of medical resources, relieving pressure on large hospitals by enhancing these facilities, thus optimizing resource allocation.
Effect of Temperature on Corrosion of L245 Steel Under CO2-SRB Corrosion System
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Optimization of Low-Carbon Operation in a Combined Electrical, Thermal, and Cooling Integrated Energy System with Liquid Carbon Dioxide Energy Storage and Green Certificate and Carbon Trading Mechanisms
1. Introduction The global push for carbon neutrality has intensified the demand for innovative solutions in energy systems. Integrated energy systems (IESs), capable of integrating electricity, heating, and cooling energy, offer significant potential for improving energy efficiency, promoting renewable energy adoption, and reducing greenhouse gas emissions [1,2].
Integrative multi-omics analysis reveals the translational landscape of the plant-parasitic nematode Meloidogyne incognita - Communications Biology
Abstract Root-knot nematodes (RKNs) of the genus Meloidogyne pose the most significant threats to global food security due to their destructive nature as plant-parasitic nematodes. Although significant attention has been devoted to investigating the gene transcription profiling of RKNs, our understanding of the translational landscape of RKNs remains limited.
ECE-CYC1 Transcription Factor CmCYC1a May Interact with CmCYC2 in Regulating Flower Symmetry and Stamen Development in Chrysanthemum morifolium
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Carbon Policies and Liner Speed Optimization: Comparisons of Carbon Trading and Carbon Tax Combined with the European Union Emissions Trading Scheme
1. Introduction With the intensifying challenges of global climate and environmental degradation, the need for emissions reduction in the shipping sector has become a critical focus globally. As a crucial element of the global transportation network and a key facilitator of international trade, the shipping industry has gained significant attention in discussions on sustainability.
Baseline and cumulative Chinese visceral adiposity index and diabetic kidney disease: A prospective cohort study
Corresponding Author Yanan Ma PhD Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention, Ministry of Education, Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, China Correspondence Yanan Ma, Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention, Department of Biostatistics and Epidemiology, School of Public Health, Ministry of Education, China Medical University, No.77 Puhe Road,...
Adaptive Optimization and Dynamic Representation Method for Asynchronous Data Based on Regional Correlation Degree
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Efficacy and safety of novel multiple-chain DAP-CAR-T cells targeting mesothelin in ovarian cancer and mesothelioma: a single-arm, open-label and first-in-human study | Genome Medicine | Full Text
This was a researcher-initiated, single-arm, open-label, single-center, first-in-human clinical trial (ChiCTR2100046544) designed to evaluate the safety and efficacy of KT032 in patients with mesothelin-expressing advanced solid tumors between August 2021 and February 2024, at the First Affiliated Hospital of Nanjing Medical University. Tumor biopsies were evaluated for mesothelin (MSLN) expression at enrolment, followed by leukapheresis and KT032 manufacture.
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