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Articles by Robert Dickson
Surgical waste from stereotactic glioma biopsies contains clinically relevant tumor DNA
Abstract Stereotactic needle biopsy is an established approach for sampling gliomas in deep, midline, or eloquent brain regions, but tissue acquisition remains constrained by the need to preserve material for histopathology, molecular testing, and research. During routine specimen handling, needle rinse fluid, expelled aspiration material, and gauze-associated debris are discarded as waste. This waste could contain diagnostically relevant tumor material.
The role of the respiratory microbiome in acute and chronic respiratory diseases
Abstract The lungs, once considered sterile, are now known to contain diverse, dynamic microbial communities that are metabolically active and immunologically consequential even in health. In respiratory disease, these communities undergo quantitative and compositional changes that predict clinical trajectories and may contribute to pathogenesis.
New Jersey Launches Employee Separation Reporting Portal
New Jersey requires employers to report every employee separation to the state’s Department of Labor (NJDOL) under New Jersey Public Law, Chapter 120 (S2357). As discussed in a prior GT Alert, lawmakers adopted the mandate in 2023. However, the state paused implementation while it built the reporting system. The Division of Unemployment Insurance Employer Response Portal is now live.
The Role of the Respiratory Microbiome in Pneumonia
Keywords Lung microbiome Microbial ecology Pneumonia Get full text access Log in, subscribe or purchase for full access. References 1. Koch, R. Die Aetiologie der Tuberkulose Mittheilungen aus dem Kaiserlichen Gesundheitsamte Verlag von August Hirschwald, 1884; 1-88 2. Cotran, R. ∙ Kumar, V. ∙ Collins, T. ... Robbins pathologic basis of disease Saunders, 1999 3. Dickson, R.P. ∙ Erb-Downward, J.R. ∙ Martinez, F.J. ... The microbiome and the respiratory tract Annu Rev Physiol. 2016; 78:481-504 4. Hilty, M.
The Gut Microbiome and Short-Chain Fatty Acid Metabolites in Sepsis
Keywords Sepsis Microbiome Metabolites Metabolism Short chain fatty acids Get full text access Log in, subscribe or purchase for full access. References 1. Fine, J. ∙ Frank, H. ∙ Schweinburg, F. ... The bacterial factor in traumatic shock Ann N Y Acad Sci. 1952; 55:429-445 2. Ferraro, F.J. ∙ Rush, Jr., B.F. ∙ Simonian, G.T. ... A comparison of survival at different degrees of hemorrhagic SHOCK IN germ-free and germ-bearing rats Shock. 1995; 4:117 3. Chanderraj, R. ∙ Admon, A.J. ∙ He, Y. ...
Case report: Is it contagious?
Case report: Is it contagious? A patient with shingles at Dr. Robert Dickson's clinic has a valid concern about virus spreading. Register for free access or login. Canadian Healthcare Network is an independent online community for Canadian healthcare professionals in medicine and pharmacy. It is the online home of the Medical Post and Pharmacy Practice + Business.
MIDAS: rapid, multiplexed molecular profiling for integrated host–pathogen analysis - Nature Communications
Abstract Addressing the need for integrated molecular analysis in complex infectious conditions requires technologies that rapidly quantify both pathogens and host responses. This is particularly relevant in sepsis research, where existing tools typically measure either microbial or host biomarkers.
Alterations in the intestinal microbiome and immune dysregulation in infants with CHD undergoing cardiopulmonary bypass: a scoping review
Hostname: page-component-5cf477f64f-h6p2m Total loading time: 0 Render date: 2025-04-01T11:43:32.889Z Has data issue: false hasContentIssue false Published online by Cambridge University Press: 14 February 2025 Andrew J. Prout [Opens in a new window] , Show author details Abstract References Keywords gastrointestinal microbiomeimmune systemcardiopulmonary bypasspaediatric Type Review Information Cardiology in the Young , Volume 35 , Issue 3 , March 2025 , pp.
The First NCC Digital Industrial Park in Kano State: A Game-Changer for Nigeria
Robert Stuart Dickson · Follow 1 min read · -- The NCC Digital Industrial Park in Kano State Nigerian Communications Commission (NCC) is set to complete its first Digital Industrial Park (DIP) project in Kano State by January 2023. This groundbreaking initiative is expected to revolutionize the digital landscape in Nigeria, fostering innovation and economic growth.
How to Secure Your Social Media Accounts: A Comprehensive Guide
Robert Stuart Dickson · Follow Just now -- Secure Your Social Media Accounts, in today’s digital world, is an inevitable part of everyone’s life. Whether it’s sharing personal updates or networking professionally, Facebook, Instagram, Twitter, and Snapchat are all action-packed platforms. But with such convenience comes the significant risk that cybercriminals are targeting social media accounts, so protecting those accounts is key to safeguarding your personal information and online presence.
Crypto Market Recap: Bitcoin Stalls as Stablecoin Bill Takes Center Stage
Robert Stuart Dickson · Follow Just now -- The cryptocurrency market has been a hotbed of activity in recent weeks, with Bitcoin’s price stalling and a new stablecoin bill taking center stage. In this comprehensive Crypto Market Recap, we’ll dive into the latest developments, analyze the factors influencing Bitcoin’s performance, and explore the implications of the proposed stablecoin legislation.
Red Blood Cells Capture and Deliver Bacterial DNA to Drive Host Responses During Polymicrobial Sepsis
ResearchInflammationPulmonology Open Access | 10.1172/JCI182127 J Clin Invest. https://doi.org/10.1172/JCI182127. Copyright © 2024, Lam et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Community-Acquired Pneumonia: A Review
1. McDermott KW, Roemer M. Most frequent principal diagnoses for inpatient stays in US hospitals, 2018. Published July 2021. Accessed December 14, 2023. 2. Rhee C, Jones TM, Hamad Y, et al; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals. JAMA Netw Open. 2019;2(2):e187571. doi:10.1001/jamanetworkopen.2018.7571PubMedGoogle ScholarCrossref 3.
Reevaluating Piperacillin-Tazobactam Mortality-Reply
Reevaluating Piperacillin-Tazobactam Mortality Reevaluating Piperacillin-Tazobactam Mortality Christopher A. Darlow, MB, BChir, PhD; Alessandro Gerada, MD; William Hope, BM, BS, PhD Reevaluating Piperacillin-Tazobactam Mortality Chi-Kuei Hsu, MD; Chih-Cheng Lai, MD In Reply We appreciate the Letters to the Editor by Hsu and Lai, Darlow et al, and Chao in response to our retrospective cohort study.1 Hsu and Lai inquired regarding the large number of patients with an unclear source of infection.
From gut to lung and back again: early life microbiota in cystic fibrosis
Footnotes Conflict of interest: The authors have no potential conflicts of interest to disclose. Received March 26, 2024. Accepted March 27, 2024. View Full Text ERS Members myERS - ERS members : log in with your myERS username and password. INDIVIDUALS Login as an individual user. Forgot your username or password? If your library has a subscription, you may already be logged in via your IP address. Otherwise you may be able to log in via one of the following routes.
Urgent Need for Regulatory Oversight of Human Cells, Tissues, and Cellular and Tissue-Based Products
When Shandra Eisenga underwent an elective spine surgery in April 2023, her hope was that it would let her spend more quality time with her grandchildren. A 57-year-old resident of Marion, Michigan, Shandra had already undergone 3 kidney transplants and expected that a spinal fusion procedure would improve her chronic back pain. Yet in the months after her surgery, she developed drainage from her surgical site, lymphadenopathy, night sweats, and 20 lb (9 kg) of unintentional weight loss.
New Supports and Developments in the Nursing Home Sector
The nursing home sector in Ireland has evolved in recent years with the majority of nursing home services now being provided by the private sector. While this sector still faces many challenges, new supports have recently been introduced to enable the sector to focus on providing high quality care to meet the needs of Ireland’s growing population. In addition, draft guidance on the design of nursing homes has also been published and is under consideration.
Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection Edward T. Qian, MD, MSc; Jonathan D. Casey, MD, MSc; Adam Wright, PhD; Li Wang, MS; Matthew S. Shotwell, PhD; Justin K. Siemann, PhD; Mary Lynn Dear, PhD; Joanna L. Stollings, PharmD; Brad D. Lloyd, RRT-ACCS; Tanya K. Marvi, MD; Kevin P. Seitz, MD, MSc; George E. Nelson, MD; Patty W. Wright, MD; Edward D. Siew, MD, MSc; Bradley M. Dennis, MD; Jesse O. Wrenn, MD, PhD; Jonathan W. Andereck, MD, MBA; Jin H. Han, MD, MSc; Wesley H.
Robust airway microbiome signatures in acute respiratory failure and hospital-acquired pneumonia - Nature Medicine
Abstract Respiratory microbial dysbiosis is associated with acute respiratory distress syndrome (ARDS) and hospital-acquired pneumonia (HAP) in critically ill patients. However, we lack reproducible respiratory microbiome signatures that can increase our understanding of these conditions and potential treatments.
Infrastructures in Flux: Bridging Technical Evolution with Business Ambition
In a business environment increasingly characterized by agility, customer-centricity, and rapid innovation, technical infrastructures are no longer merely supporting components. They are at the forefront of an organization’s growth strategies, mainly as companies make significant efforts to adjust to market disruptions, strengthen customer relationships, and maintain a competitive advantage.
Case of the Quarter: BRUE in an 8-week old Infant
This quarter the Montgomery County Hospital District EMS (MCHD) brings you a case that can be very anxiety-provoking for EMS providers. A potential pediatric cardiac arrest that, much to our relief, is awake and normal appearing on our arrival. Now that the initial adrenalin rush settles, EMS is responsible for assessing the potential serial killers provoking this patient’s initial presentation.
Traumatic brain injuries: Keep it simple!
The MCHD Paramedic Podcast By Devin Shumway, MD; Casey Patrick, MD; and Robert Dickson, MD Traumatic brain injuries (TBIs) are a common injury pattern and can result in significant morbidity and mortality. Injury to the brain tissue can affect the functionality of the brain and can have a prolonged effect on both mortality and quality of life [1].
Traumatic brain injuries: Keep it simple!
The MCHD Paramedic Podcast was launched in early 2018 in an effort to provide easily consumable core-content EMS education and insights from prehospital care thought leaders. The Clinical Services Department of The Montgomery County Hospital District EMS service developed the podcast as a tool to better engage and disseminate continuing education to our MCHD medics as well as first responders and EMS professionals nationwide.
Navigating Title Insurance in Seattle, WA Real Estate Deals
Buying property in Washington state involves a process known as a title search that makes sure there are no problems such as liens, unpaid taxes, and prior claims to the land. However, a title search can overlook these issues, which is where title insurance comes in to protect the buyer. Title insurance provides the buyer with a defense against a claim or other issue, but the insurer may decide to not uphold their duties to the insured.
Legal Considerations for Commercial Real Estate Transactions in Seattle, WA
Real estate transactions can become complex very quickly, largely due to the many rules and restrictions in the industry. While the federal government has overarching rules about how to sell a piece of property, Washington D.C. officials aren’t the only ones who get a say. A real estate lawyer in Seattle, WA, has to constantly stay on their toes when it comes to changing expectations and sensibilities. In fact, legal considerations can vary from street to street, depending on what’s being sold.
Case of the Quarter: The Terrible Trach
Editor's Note: EMS World’s "Case of the Quarter" feature is developed by Texas’ Montgomery County Hospital District EMS to share lessons learned from real-life calls and their outcomes. Click here for the MCHD Paramedic Podcast discussing this case.
The gut microbiome in ARDS: from the “whether” and “what” to the “how”
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Prehospital treatment options for hyperkalemic emergencies
By Konner Cue, MD; Casey Patrick, MD; Brad Ward, EMT-P; and Robert Dickson, MD Let’s review hyperkalemia to: Know the red flag historical features suggestive of hyperkalemia Recognize EKG features suggestive of severe hyperkalemia and patients at high risk of cardiac arrest Understand prehospital treatment options for hyperkalemic emergencies, including IV calcium carbonate, nebulized albuterol and sodium bicarbonate therapy Hyperkalemia is one of the most dangerous electrolyte emergencies,...
Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients in general care in the Veterans Health Administration 2013-19: multicenter, retrospective cohort study
Research Racial bias and...
Is the lung microbiome alive? Lessons from Antarctic soil
Jennifer M. Baker, Robert P. Dickson European Respiratory Journal 2021 58: 2100321; DOI: 10.1183/13993003.00321-2021 Abstract Is the lung microbiome alive? What we can learn from 1) the cold, dry, salty soil of Antarctica and 2) an elegant new translational study in the European Respiratory Journal. A new essay by @robertpdickson and @jenn_bak_.
Systems of Care that Scale: How EMS Leaders Are Building the Future
As the pandemic subsides, EMS leaders and organizations are not just in recovery mode; they are also reevaluating and restructuring their care systems based on what they’ve learned.
Sailing in Outback Australia?
Sailing in Outback Australia? by Robert Dickson 1 Mar 17:59 PST Outback sailing in the Tiwal © Melinda Henshaw In June of this year Kiwi sailor, Melinda Henshaw, announced she wanted to see ‘the real Australia’. It was a challenge I couldn’t resist. So we loaded the TIWAL 2 and TIWAL 3 into the Pajero and off we went. In 1830, explorer Charles Sturt managed to get a sailboat far up the Murray and Darling rivers. Now over 120 years later, technology has proven benefits for adventurers.
Racial Bias in Pulse Oximetry Measurement
To the Editor: Oxygen is among the most frequently administered medical therapies, with a level that is commonly adjusted according to the reading on a pulse oximeter that measures patients’ oxygen saturation. Questions about pulse oximeter technology have been raised, given its original development in populations that were not racially diverse.1,2 The clinical significance of potential racial bias in pulse oximetry measurement is unknown.
Racial Bias in Pulse Oximetry Measurement
To the Editor: Oxygen is among the most frequently administered medical therapies, with a level that is commonly adjusted according to the reading on a pulse oximeter that measures patients’ oxygen saturation. Questions about pulse oximeter technology have been raised, given its original development in populations that were not racially diverse.1,2 The clinical significance of potential racial bias in pulse oximetry measurement is unknown.
COVID-19 reinfection FAQs
How to approach high-risk exposures in paramedics previously infected with SARS-CoV-2 By Casey Patrick, MD, FAEMS; and Robert Dickson, MD, FAEMS As the first anniversary of the COVID-19 pandemic approaches, more questions have developed around the area of potential SARS-CoV-2 reinfection. It is currently unknown how long immunity lasts following infection, but past coronavirus literature suggests that prolonged protection is far from guaranteed.
Sandbagging In Irish Share Purchase Agreements
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OP-ED: Now is the time to speed up the transition to cleaner energy sources
Can Bangladesh aim for a low-carbon future? We are at a critical moment for the future of our planet. Temperatures are rising, storms are raging, and crops are failing across the world. In the 14 months in the run up to the next United Nations Climate Change Conference, COP26, being held in Glasgow in November 2021, we must increase climate ambition around the world to protect our planet. Accelerating the transition to renewable energy sources is a key part of the solution.
Ligand electronic fine-tuning and its repercussion on the photocatalytic activity and mechanistic pathways of the copper-photocatalysed aza-Henry Reaction.
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Preparation, Response and Lessons Learned from Hurricane Harvey
Houston-area EMS agencies put to the test responding to Hurricane Harvey’s epic flooding Rescue boats fill Tidwell Road as they help flood victims evacuate as floodwaters from Tropical Storm Harvey rise Monday, Aug. 28, in Houston. AP Photo/David J. Phillip Hurricane Harvey made landfall on Friday, August 25, at 11p.m., between Port Aransas and Port O’Connor, Texas. A Category 4 hurricane, it was the strongest to hit Texas since 1961.
Jeff Irish and Robert C Dickson: What you need to know about fluoridation
By Jeff Irish and Robert C. Dickson, M.D. Spokane’s voters have rejected water fluoridation three times. City council should respect the enduring wisdom of our citizens – which has been based on sound science all along – to keep our water safe and clean. Fluoridation has always been controversial, but there’s agreement on several objectives: We all want fewer cavities, proven safety, and wise use of our tax dollars. Let’s examine each issue. Is it safe?
The perils of premature phenotyping in COVID-19: a call for caution
Lieuwe D.J. Bos, Pratik Sinha, Robert P. Dickson European Respiratory Journal 2020 56: 2001768; DOI: 10.1183/13993003.01768-2020 Abstract By prematurely phenotyping patients with COVID-19, we and our patients are exposed to considerable and preventable risk. If data-driven phenotypes are not insisted upon, our cognitive biases guarantee that we'll end up with phenotype-driven data.
The perils of premature phenotyping in COVID: a call for caution
Lieuwe D. J. Bos, Pratik Sinha, Robert P. Dickson European Respiratory Journal 2020; DOI: 10.1183/13993003.01768-2020 Abstract By prematurely phenotyping patients with COVID-19, we expose ourselves and our patients to considerable and preventable risk. If we do not insist on data-driven phenotypes, our cognitive biases guarantee that we'll end up with phenotype-driven data. Body The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) poses an unprecedented global healthcare challenge.
Making the case for causality: what role do lung microbiota play in idiopathic pulmonary fibrosis?
Robert P. Dickson, Sergio Harari, Martin Kolb European Respiratory Journal 2020 55: 2000318; DOI: 10.1183/13993003.00318-2020 Abstract Yet more evidence that the lung microbiome plays a role in idiopathic pulmonary fibrosis. But how close are we to proving causality? An editorial from Dickson, Harari and Kolb in the ERJ.
Atomic Structure of a Fluorescent Ag8 Cluster Templated by a Multistranded DNA Scaffold
Multinuclear silver clusters encapsulated by DNA exhibit size-tunable emission spectra and rich photophysics, but their atomic organization is poorly understood. Herein, we describe the structure of one such hybrid chromophore, a green-emitting Ag8 cluster arranged in a Big Dipper-shape bound to the oligonucleotide A2C4.
Kudzu and sleeper cells: the varied ecology of respiratory infections
If you have spent time driving in the southern USA, you have witnessed the vast green scourge that is kudzu. Innocently introduced to America from Japan at the 1876 Centennial Exposition, the kudzu vine has infested the American south, blanketing roadsides and smothering competing vegetation (figure 1). Kudzu can grow a foot (∼30 cm) a day, scales trees and telephone poles, and creates a dense shade that deprives everything beneath it of sunlight.
The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease
IntroductionThe microbiome is defined as the “ecological community of commensal, symbiotic and pathogenic organisms that share our body space” (1). Most studies of host and microbiome interaction in the human have focused almost exclusively on bacteria, biotic factors, and the host. These complex communities of microbiota that inhabit environments such as the lung, skin, or gut are now appreciated for their role in maintaining organ, tissue, and immune homeostasis.
Referral processes and wait times in primary care
Research ArticleResearch Ieva Neimanis, Kathryn Gaebel, Robert Dickson, Richard Levy, Cindy Goebel, Angelo Zizzo, Anne Woods and John Corsini Canadian Family Physician August 2017, 63 (8) 619-624; Available Languages Abstract Objective To evaluate the response times to requests for consultations from FPs and the wait times for patient appointments. Design Mailed invitation to participate in a survey about non-FP specialist consultation requests from April 28 to May 9, 2014. Setting Hamilton, Ont.
The Citizen bids adieu
By Robert Dickson Publisher Our efforts to find a successor to take on this newspaper have not borne fruit, so this will be the last issue of The Carrboro Citizen. This is one of the most gut-wrenching decisions I’ve ever had to make. This little newspaper has succeeded beyond our wildest imaginings. In five-and-a-half years we’ve become part of the fabric of our community. You’ve told us over and over you trust and respect what we write. Honest and straightforward journalism has defined our efforts.
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