Ryan Jackson on Muck Rack

Ryan Jackson

Canada
As seen in: Nature, NFL Network, Financial Post, San Francisco Chronicle, Game Developer, Morningstar, Bangor Daily News, The Indianapolis Star, ABA Banking Journal, First Voice and
Certified Management Consultant (CMC), Entrepreneur, Mentor and Businessman
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Ryan

Contact Ryan, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

|
By Jingkun Zeng, Zhiyuan Cheng, Huadong Chen, Zhaojun Wang, Jared Thompson, Kadin T. Crosby, Hesong Han, Arushi Singhal, Wayne Ngo, Chenglong Xia, Daniel Rosas-Rivera, Zeyuan Zhang, Ying Mao, Morgan E. Diolaiti, Giselle Lee, John F. X. Diffley, Yixuan Song, Longhui Qiu, Nathan M. Krah, Niren Murthy, Ryan Jackson, Yang Liu , Alan Ashworth , Jennifer Doudna, Min Hyung Kang
| Nature
Abstract Genetic mutations that drive cancer often occur in tumor suppressor proteins, including the p53 transcription factor which is altered in ~40-50% of cases1,2. However, current therapies fail to target most such mutations because the mutant proteins typically lack defined drug-binding pockets, and restoring the endogenous function has proven challenging.
Open in Who Shared Issue with article?

RNA-triggered cell killing with CRISPR–Cas12a2

|
By Paul Scholz, Jared Thompson, Kadin T. Crosby, Nathan M. Krah, Robin Back, Rebekka Medert, Christian Zurek, Oleg Dmytrenko, Emily Wilson , Jared Rutter, Xiaoyang Zhang, Michael Krohn, Ryan Jackson, Yang Liu , Torsten Fauth, Grant Schlauderaff, Zachary A. Berkheimer, Alivia Jolley, Dirk Sombroek, Friso T. Schut
| Nature
Abstract Selectively eradicating target cells on the basis of their genetic or transcriptional identity remains important in basic research, medicine, biotechnology and agriculture1,2,3. For applications involving bacteria, CRISPR nucleases offer promising options due to their ability to enact RNA-guided counterselection4,5,6,7; however, using these same nucleases for counterselection in eukaryotes has proven much more restrictive8,9,10,11,12,13,14.
Open in Who Shared Issue with article?

RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity - Nature

|
By Oleg Dmytrenko, Max von Kleist, Redmond P. Smyth, Sebastian Glatt, DIrk Heinz, Ryan Jackson, Kadin T. Crosby, Max Krebel, Bamidele Filani
| Nature
Abstract In all domains of life, tRNAs mediate the transfer of genetic information from mRNAs to proteins. As their depletion suppresses translation and, consequently, viral replication, tRNAs represent long-standing and increasingly recognized targets of innate immunity1,2,3,4,5. Here we report Cas12a3 effector nucleases from type V CRISPR–Cas adaptive immune systems in bacteria that preferentially cleave tRNAs after recognition of target RNA.
Open in Who Shared Issue with article?
See all 72 licensed articles (73 Total)

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Get in touch with Ryan

Contact Ryan, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack
 •  Privacy  •  Terms  •  Security and Legal  •   •   •   • 

© 2026 Muck Rack

SOC 2® Certified