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Sarah Gough

Verified
  • Digital Video Assistant Editor, Sky News
London
As seen in: Sky News, MSN Ireland, MSN UK, Nature, Channel 4 News, HuffPost UK, Lexology, Isle of Wight Radio, Manx Radio, MKFM 106.3 FM, Original 106 FM and
Digital video assistant editor @SkyNews. Previously US producer for Sky News in LA and DC. Before that @Channel4News digital/podcasts. @JSchofieldTrust fellow
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Author Correction: Titration of RAS alters senescent state and influences tumour initiation

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By Adelyne Chan, Haoran Zhu, Masako Narita, Liam Cassidy, Andrew Young, Camino Bermejo-Rodriguez, Aleksandra T. Janowska, Hung-Chang Chen, Sarah Gough Verified, Naoki Oshimori, Lars Zender, Sarah Aitken, Matthew Hoare, Masashi Narita
| Nature Verified
Correction to: Nature https://doi.org/10.1038/s41586-024-07797-z Published online 7 August 2024 In the originally published version of this article, the t-SNE plot coloured by gene expression, labelled “Cdkn1a” (p21) in Extended Data Fig. 2e, was incorrect and instead showed “Cdkn1b” (p27). This has now been corrected in the HTML and PDF versions of the article to display the appropriate Cdkn1a data. This error does not affect the text or conclusions of the study.
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ethylene oxide sterilisation - NW England

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By Sarah Gough Verified
| VetNurse.co.uk
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Titration of RAS alters senescent state and influences tumour initiation - Nature

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By Haoran Zhu, Masako Narita, Sarah Gough Verified, Lars Zender, Sarah Aitken, Matthew Hoare, Camino Bermejo-Rodriguez, Aleksandra T. Janowska
| Nature Verified
Abstract Oncogenic RAS-induced senescence (OIS) is an autonomous tumour suppressor mechanism associated with premalignancy1,2. Achieving this phenotype typically requires a high level of oncogenic stress, yet the phenotype provoked by lower oncogenic dosage remains unclear. Here we develop oncogenic RAS dose-escalation models in vitro and in vivo, revealing a RAS dose-driven non-linear continuum of downstream phenotypes.
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