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Articles by Yi You
NADPH-cytochrome P450 reductase involved in the multi-resistance of Aphis spiraecola to imidacloprid and lambda-cyhalothrin
Abstract NADPH-cytochrome P450 reductase (CPR) serves as the obligate electron donor for cytochrome P450 enzymes and is essential for xenobiotic metabolism and detoxification. However, its involvement in insecticide resistance of Aphis spiraecola remains unclear. In this study, the open reading frame (ORF) of the A. spiraecola CPR gene was cloned and characterized.
Exploratory analysis of morphology–hemodynamics–perfusion relationships after intracranial stenting in severe intracranial atherosclerotic stenosis
Abstract Background: Intracranial artery stenting is widely used to treat severe intracranial atherosclerotic stenosis (ICAS). However, the relationships among post-stenting morphological remodeling, hemodynamic recovery, and perfusion imaging changes remain unclear. Methods: This retrospective single-center study included 131 patients with severe ICAS (70–99%) who underwent intracranial stenting.
Plasma-activated media inhibits epithelial-mesenchymal transition and ameliorates intestinal fibrosis through the PPARγ/TGF-β1/SMAD3 pathway
Citation: You Y, Shen Y, Yang Y, Wei X, Zhou Y, Tan F, et al. (2025) Plasma-activated media inhibits epithelial-mesenchymal transition and ameliorates intestinal fibrosis through the PPARγ/TGF-β1/SMAD3 pathway. PLoS One 20(10): e0335225. https://doi.org/10.1371/journal.pone.0335225 Editor: Vinay Kumar,, Pennsylvania State University Hershey Medical Center, UNITED STATES OF AMERICA Received: July 23, 2025; Accepted: October 8, 2025; Published: October 22, 2025 Copyright: © 2025 You et al.
Overexpression of Acetylation‐Defective Heat Shock Protein 60 Inhibits the Proliferation of Nucleopolyhedrovirus in Bombyx mori
Conflicts of Interest The authors declare no conflicts of interest. References , , , et al. 2016. “Groel/Es Inhibitors As Potential Antibiotics.” Bioorganic & Medicinal Chemistry Letters 26, no. 13: 3127–3134. , , , et al. 2001. “Genome Sequence of a Baculovirus Pathogenic for Culex Nigripalpus.” Journal of Virology 75, no. 22: 11157–11165. , , , et al. 2020. “Hsp60 Post-Translational Modifications: Functional and Pathological Consequences.” Frontiers in Molecular Biosciences 7: 95. , , , , , and . 2002.
Degradation of sulfur hexafluoride and its application in the synthesis of esters and amides
Degradation of sulfur hexafluoride and its application in the synthesis of esters and amides To meet the increasing demand on degrading the greenhouse gas sulfur hexafluoride (SF6) used in electric power industry, which causes growing environmental pressure, utilizing it in practical organic synthesis could offer an ideal solution.
Deficiency of histamine H2 receptors in parvalbumin-positive neurons leads to hyperactivity, impulsivity, and impaired attention
Keywords histamine H2 receptor attention deficit hyperactivity disorder substantia nigra pars reticulata parvalbumin-positive neuron substantia nigra pars compacta intermediate layers of superior colliculus histamine dopaminergic neurons Get full text access Log in, subscribe or purchase for full access. References 1. Biederman, J. Attention-deficit/hyperactivity disorder: a selective overview Biol. Psychiatry. 2005; 57:1215-1220 2. Thapar, A. ∙ Cooper, M.
Treating myocardial infarction via a nano-ultrasonic contrast agent-mediated high-efficiency drug delivery system targeting macrophages
Research Article APPLIED SCIENCES AND ENGINEERING INTRODUCTION Ischemic heart disease remains a leading cause of mortality and disability worldwide, affecting approximately 126 million people globally (1, 2). Myocardial infarction (MI) is the most severe form of ischemic heart disease (3). Now, adverse ventricular remodeling and heart failure following MI continue to be the primary contributors to patient mortality (4).
Manipulation of Gaseous Ions with Acoustic Fields at Atmospheric Pressure
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT Yi You Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44242, United States Division of Instrumental Analytics (1.3), Federal Institute for Materials Research and Testing (BAM), Berlin D-12489, Germany , Julia L.
Manipulation of Gaseous Ions with Acoustic Fields at Atmospheric Pressure
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT Yi You Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44242, United States Division of Instrumental Analytics (1.3), Federal Institute for Materials Research and Testing (BAM), Berlin D-12489, Germany , Julia L.
Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex
Muckli, L. , Ehrlich, I., Ortiz-Tudela, J., Tan, Y. Y., Muckli, L. and Shing, Y. L. (2023) Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex. Journal of Neuroscience, (Accepted for Publication) Text 315289.pdf - Accepted Version Restricted to Repository staff only 419kB Item Type: Articles Additional Information: This work was funded by a European Research Council Starting Grant (ERC-2018-StG-PIVOTAL-758898).
Deacetylation of ACO2 Is Essential for Inhibiting Bombyx mori Nucleopolyhedrovirus Propagation
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,2,†, 1,2,†, 1,2, 1,2, 1,2, 1,2, 1,2 and 1,2,* 1 Institute of Biochemistry, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China 2 Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, Hangzhou 310018, China * Author to whom correspondence should be addressed. † These authors contributed equally to this work.
Free occupying mechanism of simulated tetravalent waste ions in Gd2Zr2O7 and performance evaluation of the waste forms
RESEARCH ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as https://doi.org/10.1111/jace.19303 Abstract To extend the practicability of ceramics in immobilizing nuclear waste with fluctuant composition, structural design should be abandoned.
Synthesis of 2-trifluoromethyl benzimidazoles, -benzoxazoles, and -benzothiazoles via condensation of diamines or amino(thio)phenols with CF3CN
Synthesis of 2-trifluoromethyl benzimidazoles, -benzoxazoles, and -benzothiazoles via condensation of diamines or amino(thio)phenols with CF3CN Bo Lin, Yunfei Yao, Minze Wu, Lu Qin, Shouxiong Chen, Yi You and Zhiqiang Weng Abstract A new and efficient method is developed for the synthesis of 2-trifluoromethyl benzimidazoles, benzoxazoles, and -benzothiazoles in good to excellent yields by condensation of diamines or amino(thio)phenols with in situ generated CF3CN.
Determination of Broadband-Light Atomic Absorption through Interferometric Spectrometry with a Spatial Heterodyne Spectrometer
Determination of Broadband-Light Atomic Absorption through Interferometric Spectrometry with a Spatial Heterodyne Spectrometer Xunyu Li, Jens Riedel and Yi You Abstract A spatial heterodyne spectrometer (SHS) was combined with a flame atomic absorption (FAA) setup to reveal the analytical potential of SHS to be used as a tool for high-resolution atomic absorption studies.
N6-methyladenosine-dependent modification of circGARS acts as a new player that promotes SLE progression through the NF-κB/A20 axis - Arthritis Research & Therapy
Abstract Background Certain circRNAs could be used as biomarkers to determine the risk of development and/or severity of systemic lupus erythematosus, and their new function in the regulation of gene expression has motivated us to investigate their role in SLE Methods Experimental methods including qRT-PCR, RNA immunoprecipitation (RIP), pulldown, dual luciferase reporter assay, RNA interference and cell transfection, RNA fluorescence in situ hybridization, western blotting, and mass...
Water friction in nanofluidic channels made from two-dimensional crystals
Abstract Membrane-based applications such as osmotic power generation, desalination and molecular separation would benefit from decreasing water friction in nanoscale channels. However, mechanisms that allow fast water flows are not fully understood yet. Here we report angstrom-scale capillaries made from atomically flat crystals and study the effect of confining walls’ material on water friction.
Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures
Highlights • Microglia display increased extensive association with neurons in complex FSs • Microglial association displaces GABAergic presynapses surrounding neuronal soma • Microglial displacement reduces neuronal excitability and seizure susceptibility • The P2Y12 receptor mediates microglial displacement of GABAergic presynapses Summary Complex febrile seizures (FSs) lead to a high risk of intractable temporal lobe epilepsy during adulthood, yet the pathological process of complex FSs is...
Stimulated Raman scattering by intracavity mixing of nanosecond laser excitation and fluorescence in acoustically levitated droplets
Stimulated Raman scattering by intracavity mixing of nanosecond laser excitation and fluorescence in acoustically levitated droplets† Andreas Bierstedt,a Carsten Warschat,a Yi You,a Knut Rurack a and Jens Riedel *a Author affiliations * Corresponding authors a Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Straße 11, 12489 Berlin, Germany E-mail: Jens.Riedel@bam.de Fax: +4930810471003 Tel: +493081041003 Abstract Raman spectroscopy is becoming a commonly used,...
High-Throughput Underwater Elemental Analysis μJ-Laser-Induced Breakdown Spectroscopy at kHz Repetition Rates: Part I, Ultrasound-Enhanced Optical Emission Spectroscopy Towards Application Perspectives
High-Throughput Underwater Elemental Analysis μJ-Laser-Induced Breakdown Spectroscopy at kHz Repetition Rates: Part I, Ultrasound-Enhanced Optical Emission Spectroscopy Towards Application Perspectives Throughout the recent years, laser-induced breakdown spectroscopy (LIBS) has gained significant attention as a mean for simple elemental analyses. The suitability of LIBS for contactless analysis allows it to be a perfect candidate for underwater applications.
High-Throughput Underwater Elemental Analysis μJ-Laser-Induced Breakdown Spectroscopy at kHz Repetition Rate: Part II, Understanding High Repetition-Rate from a Fundamental Perspective
High-Throughput Underwater Elemental Analysis μJ-Laser-Induced Breakdown Spectroscopy at kHz Repetition Rate: Part II, Understanding High Repetition-Rate from a Fundamental Perspective The technological advances in lasers enabled the wide applications of laser-induced breakdown spectroscopy (LIBS) as a powerful analytical mean for elemental analyses.
Near‐IR to Near‐IR Upconversion Luminescence in Molecular Chromium Ytterbium Salts
Abstract Upconversion photoluminescence in hetero‐oligonuclear metal complex architectures featuring organic ligands is an interesting but still rarely observed phenomenon, despite its great potential from a basic research and application perspective.
A Dual Response DNA Probe for Simultaneously Monitoring Enzymatic Activity and Environmental pH by Nanopores - Wu - - Angewandte Chemie International Edition - Wiley Online Library
Communication A Dual Response DNA Probe for Simultaneously Monitoring Enzymatic Activity and Environmental pH by Nanopores Hai-Chen Wu Corresponding Author E-mail address: haichenwu@iccas.ac.cn Institute of Chemistry Chinese Academy of Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Zhongguancun North First Street 2, 100190 Beijing, CHINA Search for more papers by this author PDF PDF Share Abstract Both protease overexpression and local pH in tumor environment are key...
Spatial, temporal, and spectral characterization and kinetic investigations of a high repetition-rate laser-induced micro-plasma in air
Spatial, temporal, and spectral characterization and kinetic investigations of a high repetition-rate laser-induced micro-plasma in air Advances in laser-induced plasmas have enabled various rapid and simple analytical applications. Especially, their uses in the analyses of condensed-phase samples have drawn significant attention in the past few decades. Depending on the laser energy per pulse, various analytical goals can be achieved.
Automatic Analyte-Ion Recognition and Background Removal for Ambient Mass-Spectrometric Data Based on Cross-Correlation
Research Article First Online: 03 June 2019 Abstract Ambient mass spectrometry is a powerful approach for rapid, high-throughput, and direct sample analysis. Due to the open-air desorption and ionization processes, random fluctuations of ambient conditions can lead to large variances in mass-spectral signals over time.
Rapid and Selective DNA-Based Detection of Melamine Using α-Hemolysin Nanopore
L. Liu, Y. Sheng, Y. You, Z. Cao and H. Wu, Analyst, 2018, Accepted Manuscript , DOI: 10.1039/C8AN00580J If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
Extraordinary water adsorption characteristics of graphene oxide
The laminated structure of graphene oxide (GO) confers unique interactions with water molecules which may be utilised in a range of applications that require materials with tuneable hygroscopic properties. Precise role of the expandable interlayer spacing and functional groups in GO laminates are not completely understood till date.
Growth of NiO Nanorods, SiC Nanowires and Monolayer Graphene Via a CVD Method
Green approaches for producing high purity advanced materials have always been a challenging task. Conventional methods for converting waste materials into char by heat treatment can have limitation in making defect free and pure materials for practical applications. Herein, we report a Green-Chemical Vapor Deposition (G-CVD method) to transform waste into functional materials in various forms by condensation of gases generated from waste on a chosen substrate.
Mechanism of water transport in graphene oxide laminates
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Mechanism for Water Transport in Graphene Oxide Laminates
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Micellization and Adsorption of Heterogemini Surfactants Containing a Hydroxyl Headgroup in Aqueous Solution
The micellization of a homologous series of heterogemini surfactants, C OhpNC (m, n = 10, 8; 12, 8; 14, 8; 16, 8; and 10, 14), in aqueous solution and their adsorption at the air/water interface have been investigated by surface tension, conductivity, and fluorescence techniques. The surface tension curves of C OhpNC and C OhpNC showed two break points, corresponding to the critical concentration of the premicellar aggregation and the general micellization, respectively.
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