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Articles by Ze Yu
Shift work disrupts Immune regulation of the transcriptome in hospital nurses
Abstract Introduction: Shift work, especially night shifts in medicine, disrupts nurses‘ circadian rhythms, potentially causing immune dysregulation and health risks, with significant economic and medical burdens. The molecular mechanisms of shift work-related immune disorders are understudied. This research analyzes transcriptomes of nurses' peripheral blood mononuclear cells (PBMCs) from different shifts to identify key differentially expressed genes and explore their roles in immune regulation.
BcMFSR Is Required for Efficient Uptake of Exogenous dsRNA and Spray-Induced Gene Silencing in Botrytis cinerea
1 Introduction RNA interference (RNAi) is a conserved gene-silencing mechanism in which small RNAs (sRNAs) mediate sequence-specific regulation of gene expression, often through the degradation or translational repression of target messenger RNAs (mRNAs). In plant–pathogen interactions, RNAi plays a pivotal role in regulating pathogen virulence and coordinating host immune responses (Chen and Rechavi 2022; Zhao and Guo 2022; Weiberg et al. 2013).
Efficient Organic Fluorescence Scintillation by Engineering Anti-Kasha Triplet Energy Levels
Conflicts of Interest There are no conflicts to declare. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie73821-sup-0001-SuppMat.docx52.5 MB Supporting File: anie73821-sup-0001-SuppMat.docx.
SOFA score in gas-forming pyogenic liver abscess: a case series of seven patients with exploratory analysis of severity and mortality
Abstract Gas-forming pyogenic liver abscess (GFPLA) is a rare and highly fatal subtype of bacterial liver abscess, closely related to diabetes and hypervirulent Klebsiella pneumoniae infection. This case series analyzed seven patients diagnosed with GFPLA by CT, aiming to explore their clinical characteristics and prognosis. Among the patients, four died, with a total mortality rate of 57.1%, significantly higher than the 27.7%−37.1% reported in the literature.
Computer Science > Machine Learning
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Nanosensor-coated catheters for bladder cancer detection
A catheter equipped with an annular carbon nanotube sensor array enables real‑time, in situ three‑dimensional chemical imaging of cancer biomarkers, mapping the localization of early-stage tumours.
In Vivo Metabolic Engineering of Bladder Cancer-Derived Extracellular Vesicles for Noninvasive Cancer Detection Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleMay 6, 2026 In Vivo Metabolic Engineering of Bladder Cancer-Derived Extracellular Vesicles for Noninvasive Cancer Detection Click to copy article linkArticle link copied! Yongchun Wei Yongchun Wei State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Molecular Recognition and Biosensing, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 300071, China Ze Yu* Ze Yu State Key Laboratory of...
Adipocytes signal to recruit specific mRNAs from surrounding cells to restore expression deficits
Abstract Extracellular vesicles (EVs) are nano-sized, membrane-delimited, particles released by cells that carry signaling macromolecules. A major pathway of EV production is potentiated by neutral sphingomyelinase 2 (SMPD3/nSMAse2), an enzyme that generates ceramide from sphingomyelin.
EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization - Nature Communications
Abstract Polycomb repressive complex 2 (PRC2) mediates developmental gene repression as two classes of holocomplexes, PRC2.1 and PRC2.2. EPOP is an accessory subunit specific to PRC2.1, which also contains PCL proteins. Unlike other accessory subunits that collectively facilitate PRC2 targeting, EPOP was implicated in an enigmatic inhibitory role, together with its interactor Elongin BC.
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms - Nature Neuroscience
Abstract To myelinate axons, oligodendrocyte precursor cells (OPCs) must stop dividing and differentiate into premyelinating oligodendrocytes (preOLs), a transient cell stage during myelination that is often stalled at human demyelinating lesions. PreOLs extend processes, surveying nearby axons to begin ensheathment. The lack of genetic tools to visualize and manipulate preOLs has hindered their in-depth study.
A machine learning model for hypoglycemia risk prediction in hospitalized patients with diabetes: development and validation
Keywords Hypoglycemia Machine-learning models Inpatient Model Risk prediction Abbreviations AUC (Area under the curve) BBs (Beta-blockers) BMI (Body mass index) BP (Blood pressure) CGM (Continuous glucose monitoring) CRP (C-reactive protein) Cys-C (Cystatin-C) DBIL (Direct bilirubin) DPP4 (Dipeptidyl peptidase 4) eGFR (Estimated glomerular filtration rate) GLP-1 (Glucagon-like peptide-1) GLP-1RA (Glucagon-like peptide-1 receptor agonist) HbA1c (Hemoglobin A1c) HDL-C (High-density lipoprotein...
Transcriptomic analysis implicates the involvement of RBM20 in Fuchs’ endothelial corneal dystrophy with TCF4 repeat expansion
Loading metrics Open Access Peer-reviewed Research Article Citation: Zhang X, Yu Z, Westfall AK, Han K, Mootha VV, Xing C (2025) Transcriptomic analysis implicates the involvement of RBM20 in Fuchs’ endothelial corneal dystrophy with TCF4 repeat expansion. PLoS One 20(9): e0332512.
2‐D Scanning‐Angle Expansion of Phased Array Antenna Using Metalens
References 1, Phased Array Antenna Handbook (ser. Artech House Antennas and Propagation Library) (Artech House, 2008). 2nd ed., 1–11. 2, Antenna Theory, Analysis and Design (Wiley, 1997). 2nd ed., 1–19. 3, , and , “A Wide-Angle Scanning and Low Sidelobe Level Microstrip Phased Array Based on Genetic Algorithm Optimization,” IEEE Transactions on Antennas and Propagation 64, no. 2 (2016): 805–810.
Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis
ResearchCell biologyDevelopment Open Access | 10.1172/jci.insight.193496 JCI Insight. https://doi.org/10.1172/jci.insight.193496. Copyright © 2025, Ghotbi et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Mammalian skin is a vital barrier with the epidermis serving as its protective outer layer, continually undergoing renewal.
Combining Camera-LiDAR Fusion and Motion Planning Using Bird’s-Eye View Representation for End-to-End Autonomous Driving
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SIRT3 Inhibits Cell Proliferation of Nonsmall Cell Lung Carcinoma by Inducing ROS Production
1 Introduction Globally, lung cancer ranks as the most frequently diagnosed cancer and exhibits the highest cancer-specific mortality rate among both males and females [1]. Annually, around two million fresh instances of lung cancer are detected, leading to 1.7 million new cancer-related fatalities, accounting for 11.6% of all cancer cases and 18.4% of all cancer-related deaths worldwide [2]. Nonsmall cell lung cancer prevails as the predominant form of this malignancy [3].
Optimization of a Typical Gas Injection Pressurization Process in Underground Gas Storage
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Reliability and Validity of a Chinese Version of Adaptive Cognitive Ev
Back to Journals » Psychology Research and Behavior Management » Volume 18 Authors Yu Z, Wang Y, Li Y, Feng W Received 19 September 2024 Accepted for publication 25 December 2024 Published 16 January 2025 Volume 2025:18 Pages 105—118 DOI https://doi.org/10.2147/PRBM.S491302 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Igor Elman Ze Yu,1,2,* Youyang Wang,1,2,* Yiyun Li,3 Wei Feng1,2 1Department of...
EPOP Restricts PRC2.1 Targeting to Chromatin by Directly Modulating Enzyme Complex Dimerization
Abstract Polycomb repressive complex 2 (PRC2) mediates developmental gene repression as two classes of holocomplexes, PRC2.1 and PRC2.2. EPOP is an accessory subunit specific to PRC2.1, which also contains PCL proteins. Unlike other accessory subunits that collectively facilitate PRC2 targeting, EPOP was implicated in an enigmatic inhibitory role, together with its interactor Elongin BC.
Imatinib adherence prediction using machine learning approach in patients with gastrointestinal stromal tumor
• , , , et al. The effects of surgical cytoreduction prior to imatinib therapy on the prognosis of patients with advanced GIST . Ann Surg Oncol. ; : - . • , , , , . Survival in advanced GIST has improved over time and correlates with increased access to post-imatinib tyrosine kinase inhibitors: results from Life Raft Group Registry . Clin Sarcoma Res. ; : . • , , , , , .
Prevalence of Insomnia and Related Factors Among Cancer Outpatients in
Introduction Cancer is one of the leading causes of death in the Chinese population and a main economic burden of Chinese patients.1 Adequate sleep is essential for a better quality of life; however, 29–75% of cancer patients suffer from insomnia.
Compliant DNA Origami Nanoactuators as Size‐Selective Nanopores
1 Introduction Transmembrane nanopores are nanoscale channels that span biological membranes and play a vital role in many biological processes, such as cell communication and signal transduction.[1] Built from pore-forming proteins, biological nanopores have been repurposed with great success for biotechnological applications, such as DNA and protein sequencing,[2] sensing of biomarkers and post-translational modifications,[3] monitoring of reaction trajectories, and small molecule...
Comparative Transcriptome and sRNAome Analysis Suggest Coordinated Citrus Immune Responses against Huanglongbing Disease
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Compliant DNA Origami Nanoactuators as Size-Selective Nanopores
Abstract Biological nanopores crucially control the import and export of biomolecules across lipid membranes in cells. They have found widespread use in biophysics and biotechnology, where their typically narrow, fixed diameters enable selective transport of ions and small molecules as well as DNA and peptides for sequencing applications. Yet, due to their small channel sizes, they preclude the passage of large macromolecules, e.g., therapeutics.
Sea Clutter Suppression Based on Chaotic Prediction Model by Combining the Generator and Long Short-Term Memory Networks
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Microorganisms | Free Full-Text | Phycoremediation Potential of Salt-Tolerant Microalgal Species: Motion, Metabolic Characteristics, and Their Application for Saline-Alkali Soil Improvement in Eco-Farms
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Inter-organ steroid hormone signaling promotes myoblast fusion via direct transcriptional regulation of a single key effector gene
Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication. Cell. 2016; 164: 1248-1256 Droujinine I.A. Perrimon N. Interorgan Communication Pathways in Physiology: Focus on Drosophila. Annu. Rev. Genet. 2016; 50: 539-570 Droujinine I.A. Perrimon N. Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress. Front. Cell. Infect. Microbiol. 2013; 382 Hiller-Sturmhöfel S. Bartke A.
Site-Specific Integration of Hexagonal Boron Nitride Quantum Emitters on 2D DNA Origami Nanopores
Download Hi-Res ImageDownload to MS-PowerPointCite This:Nano Lett.
A Low-Energy Consumption Planning Method for Multi-Locomotion Wheel-Legged Mobile Robots
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A visualized analysis
Zhu JiayingWang GangMa XiaofengSun JinleiYu Ze Chen Taoyu1*21111* 1First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, China 2School of Pharmacy, China Pharmaceutical University, China The final, formatted version of the article will be published soon. Notify me Receive an email when it is updated You just subscribed to receive the final version of the article Objective.
Model-Reference Reinforcement Learning for Safe Aerial Recovery of Unmanned Aerial Vehicles
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Ground‐State Orbital Descriptors for Accelerated Development of Organic Room‐Temperature Phosphorescent Materials
Conflict of interest The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Ground‐State Orbital Descriptors for Accelerated Development of Organic Room‐Temperature Phosphorescent Materials
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
[2312.07917] On Designing Multi-UAV aided Wireless Powered Dynamic Communication via Hierarchical Deep Reinforcement Learning
[Submitted on 13 Dec 2023 ( v1 ), last revised 7 Jun 2024 (this version, v2)] Title:On Designing Multi-UAV aided Wireless Powered Dynamic Communication via Hierarchical Deep Reinforcement Learning View a PDF of the paper titled On Designing Multi-UAV aided Wireless Powered Dynamic Communication via Hierarchical Deep Reinforcement Learning, by Ze Yu Zhao and Yue Ling Che and Sheng Luo and Gege Luo and Kaishun Wu and Victor C. M.
Non-Local SAR Image Despeckling Based on Sparse Representation
1. Introduction According to the roughness of the image, synthetic aperture radar (SAR) images can be divided into three regions: homogeneous region, heterogeneous region, and extreme heterogeneous region. The scattering in homogeneous regions is relatively balanced, such as grassland and sea surface. Heterogeneous regions contain features such as edges and textures, while extreme heterogeneous regions often contain targets such as strong scatterers.
Design, Analysis, and Experiment of a Wheel-Legged Mobile Robot
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by , , , , , * and * Key Lab for Mechanism Theory and Equipment Design of Ministry of Education, Tianjin University, Tianjin 300350, China * Authors to whom correspondence should be addressed. Appl. Sci.
Linear Project-Scheduling Optimization Considering a Reverse Construction Scenario
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
[2307.14626] Multi-Agent Graph Reinforcement Learning based On-Demand Wireless Energy Transfer in Multi-UAV-aided IoT Network
arXiv:2307.14626 (cs) Download a PDF of the paper titled Multi-Agent Graph Reinforcement Learning based On-Demand Wireless Energy Transfer in Multi-UAV-aided IoT Network, by Ze Yu Zhao and 4 other authors Download PDF Submission history From: Zeyu Zhao Mr. [ view email] [v1] Thu, 27 Jul 2023 05:02:13 UTC (4,447 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart...
Dynamic Matching and Spatial Optimization of Land Use and Resource-Environment Constraints in Typical Regions of the Yellow River Basin in China
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Ze Yu , Desheng Su , Shilei Wang , Chuanchen Wei , Na Li , Yanbo Qu * and Meng Wang * School of Public Administration and Policy, Shandong University of Finance and Economics, Jinan 250014, China * Authors to whom correspondence should be addressed.
Suppression of SLC39A6‐CREB1 axis in liver cancer causes PCK1‐mediated mitochondrial dysfunction
LETTER TO THE EDITOR Ze Yu and Cheng Chen contributed equally to this work.
Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor
ResearchIn-Press PreviewOncology Open Access | 10.1172/JCI168227 J Clin Invest. https://doi.org/10.1172/JCI168227. Copyright © 2023, Jiang et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Neurofibromatosis Type 1 (NF1) is one of the most common tumor-predisposing genetic disorders. Neurofibromas are NF1-associated benign tumors.
[2303.11683] Lu-H-N phase diagram from first-principles calculations
Using a comprehensive structure search and high-throughput first-principles calculations of 1483 compounds, this study presents the phase diagram of Lu-H-N. The formation energy landscape of Lu-H-N was derived and utilized to assess the thermodynamic stability of compounds.
Superconductive materials with ${\mathrm{MgB}}_{2}$-like structures from data-driven screening
COVID-19 has impacted many institutions and organizations around the world, disrupting the progress of research. Through this difficult time APS and the Physical Review editorial office are fully equipped and actively working to support researchers by continuing to carry out all editorial and peer-review functions and publish research in the journals as well as minimizing disruption to journal access.
Untargeted metabolomic profiling identifies disease-specific and outcome-related signatures in chronic rhinosinusitis
This paper is only available as a PDF. To read, Please Download here. ABSTRACT Background Although metabolomics provides novel insights into disease mechanisms and biomarkers, the metabolic alterations in local tissues affected by chronic rhinosinusitis (CRS) are unknown. Objective This study aims to determine the metabolomic profiles of sinonasal tissues associated with different types of CRS and their treatment outcomes.
Efficient dye-sensitized solar cells based on bioinspired copper redox mediators by tailoring counterions
Efficient dye-sensitized solar cells based on bioinspired copper redox mediators by tailoring counterions In recent years, copper(II/I) complexes have attracted growing interest as redox mediators in dye-sensitized solar cells. Here, we report a new class of copper complexes bearing a bis(2-pyridylmethyl)-1,2-ethanedithiol ligand, coded as [Cu(N2S2)]2+/+, with tetrafluoroborate ([BF4]–) and hexafluorophosphate ([PF6]–) counterions.
Overcome energy loss of thermally activated delayed fluorescence sensitized-OLEDs by developing fluorescence dopant with a small singlet-triplet energy splitting
Overcome energy loss of thermally activated delayed fluorescence sensitized-OLEDs by developing fluorescence dopant with a small singlet-triplet energy splitting XinYe Wang, YiFan Zhang, Ze Yu, Yuan Wu, Dongdong Wang, ChuanMing Wu, Huili Ma, ShuYa Ning, Hua Dong and Zhaoxin Wu Abstract TADF-sensitizing-fluorescence (TSF) strategy suffered a disturbing energy loss causing by the T1 states of fluorescence dopant (FD) due to its low T1-state energy and forbidden of radiative transition.
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