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Articles by Bing Jiang
Banana starch nanoparticles exacerbate colitis by impairing intestinal barrier integrity in mice
Abstract The safety of foodborne nanoparticles has attracted significant attention in recent years. Previous studies have shown that banana-derived starch nanoparticles (BSNs) can disrupt intestinal barrier function and induce low-grade colitis in healthy mice. However, the in vivo role of these BSNs in intestinal inflammation remains unclear. Here, we show that oral exposure to BSNs aggravated the condition of the mice with DSS-induced colitis.
Omaveloxolone functions as a molecular crowbar-like degrader of STING to alleviate aging-related inflammation
Abstract Aberrant activation of the STING signaling pathway is involved with aging-related inflammation, yet no STING-targeting therapeutics are clinically approved. Here, we identify Omaveloxolone, an FDA-approved drug for Friedreich’s ataxia, as a potent STING degrader (DC50 = 118 nM, Dmax = 98.6%) via high-throughput screening.
The Recent Evolution of the Application of MicroRNAs in Eye-related Disease Research: A Systematic, Bibliometric and Visualized View of the Literature
You are already at the latest version Recent studies have demonstrated that microRNAs hold potential as diagnostic biomarkers and therapeutic targets for ophthalmic diseases. However, there is a lack of bibliometric research focused on the role of microRNAs in ophthalmology. In this study, we conducted a bibliometric analysis to examine the trends and research hotspots in the field of microRNAs in eye-related diseases, providing a visual map of both established and emerging trends.
Trends in Research Related to Pupillometry From 1999 to 2025: A Bibliometric and Visualized Analysis
Submitted: 24 February 2026 You are already at the latest version Objective: Pupillometry is a noninvasive method which measures changes in the size of the pupil intending to study cognitive processes and identify networks that are related to specific attentional states such as attention, mental effort, working memory, and many others, through monitoring pupil size.
A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility - Nature Communications
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Abstract The ubiquitin-proteasome system (UPS) represents an evolutionarily conserved machinery governing proteostasis through spatiotemporal regulation of protein degradation. While spermatogenesis involves multilayered regulatory mechanisms spanning translation to dynamic post-translational modifications (PTMs), the identity of UPS-associated E3 ligases orchestrating germ cell-specific protein turnover remains elusive.
By Tiantian Wu, Chaofeng Tu, Yuxuan Feng, Wenying Qu, Jinyi Chen, Huan Wu, Wenxin Gao, Bingya Xu, Xiangling Yu, Mingyuan Bao, Jinfu Xu, Nianchao Zhou, Haoyue Hu, Bing Jiang, Qingsong Xie, Lanlan Meng, Chen Tan, Ge Lin, Cong Shen, Xia Chen, Yueshuai Guo, Tao Zhou, Yuting Liang, Rong Hua, Yunxia Cao, Mingxi Liu, Jun Yu, Xiaoyan Huang, Yue-Qiu Tan, Bo Zheng
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Nature
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Correction: Glibenclamide attenuates neuroinflammation and promotes neurological recovery after intracerebral hemorrhage in aged rats
A Correction on Glibenclamide attenuates neuroinflammation and promotes neurological recovery after intracerebral hemorrhage in aged rats by Jiang, B., Zhang, Y., Wang, Y., Li, Z., Chen, Q., Tang, J., and Zhu, G. (2021). Front. Aging Neurosci. 13:729652. doi: 10.3389/fnagi.2021.729652 There was a mistake in Figure 4A as published. There was an error in the sham group figure content. The corrected Figure 4A appears below. The original version of this article has been updated.
The therapeutic potential of botanicals: how medicinal plants targeting autophagy can reverse metabolic-associated fatty liver disease
Abstract Metabolic-associated fatty liver disease (MAFLD) is a serious condition that can progress to cirrhosis and liver cancer. Natural herbal therapeutics, characterized by their multi-constituent and multi-target properties, as well as favorable safety profiles—particularly lower hepatorenal toxicity—are attracting significant research interest for MAFLD management. In this review, we examine their ethnopharmacological applications, with a focus on autophagy regulation.
Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice
1 Introduction Nanoparticles (NPs) used as functional carriers in biomedical research exhibit a wide range of characteristics, including variations in structure, size, and surface chemistry. This diversity leads to a broad spectrum of interactions at the cellular and organelle levels, many of which are not yet fully understood.
Assessment of Soil Heavy Metal Pollution: Characteristics, Health Risks, and Source Apportionment in Shouguang City, China
ABSTRACT Soil heavy metals (HM) are potential risk elements (PREs), evaluating soil pollution and risk levels is crucial for effective pollution control policies, contributing to sustainable development. In this investigation, 8806 surface soil samples from Shouguang City, Shandong Province, China, were systematically examined to assess the quality and source apportionment of PREs and conduct Human Health Risk Assessment (HHRA).
RNF187 Facilitates Proliferation and Migration of Human Spermatogonial Stem Cells Through WDR77 Polyubiquitination
1 Introduction Male factor infertility contributes to 50% of infertility cases globally, with the most severe form being non-obstructive azoospermia (NOA), which affects approximately 10%–15% of infertile men [1]. Spermatogonial stem cells (SSCs) are the primary source of spermatogenesis, maintaining continuous sperm production in adulthood through self-renewal and differentiation into sperm [2-4].
Contour-Parallel Tool Path Generation Method for Efficient Machining of Multi-Island Cavities
1. Introduction Structural components with multi-island cavities are critical parts of the aerospace, energy and power fields. These cavities are typically machined using computer numerical control (CNC) technology [1,2], where substantial material is removed during the rough machining stage. The tool path generation strategy has a direct effect on both machining quality and production efficiency [3].
Network pharmacology and experimental verification: Unraveling Zhiwei Fuwei Pills’s role and mechanism in angiogenesis of precancerous lesions of gastric cancer - Pengcheng Dou, Ruiping Song, Zhuangzhuang Feng, Bing Jiang, Xinyi Chen, Yuanbin Luo, Jiaojia
Introduction Gastric cancer is a malignant tumor that originates from the epithelial cells of the gastric mucosa. It has a high incidence rate, low overall survival rate, and poor treatment prognosis.
Designing nanozymes for in vivo applications - Nature Reviews Bioengineering
Abstract Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical reactions, are promising tools to address redox imbalances, metabolic disorders and immune dysregulations. However, these types of drugs suffer from uncontrolled activity, limited stability, heightened immunogenicity, lack of targeted action and adverse effects, which limit their clinical application.
Stable peptide-assembled nanozyme mimicking dual antifungal actions - Nature Communications
Abstract Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic candidates against antimicrobial resistance but suffer from low efficiency and poor stability. Here, we develop peptide nanozymes which mimic the mode of action of AMPs and AMEs through de novo design and peptide assembly. Through modelling a minimal building block of IHIHICI is proposed by combining critical amino acids in AMPs and AMEs and hydrophobic isoleucine to conduct assembly.
Peroxidase‐Like Nanozyme Activates the cGAS‐STING Pathway via ROS‐Induced mtDNA Release for Cancer Immunotherapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202401576-sup-0001-SuppMat.pdf1.9 MB Supporting Information References 1, , , , , , , , , , , Nat. Nanotechnol. 2007, 2, 577. 2, , Adv. Healthcare Mater. 2022, 11, e2101682. 3, , , , Small 2022, 18, e2203400. 4, , , Tissue Eng. Regen. Med. 2022, 19, 237. 5, , , , , , , , ACS Nano 2023, 17, 18148. 6, , , , , , Adv. Mater. 2023, 35, 2208512. 7, , , , , , , , Adv. Mater. 2023, 35, 2302335.
Sustainability | Free Full-Text | Assessing Land Resource Carrying Capacity in China’s Main Grain-Producing Areas: Spatial-Temporal Evolution, Coupling Coordination, and Obstacle Factors
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Cancer cell membrane fused liposomal platinum (IV ) prodrugs overcome cisplatin resistance in esophageal squamous cell carcinoma chemotherapy
Cancer cell membrane fused liposomal platinum (IV ) prodrugs overcome cisplatin resistance in esophageal squamous cell carcinoma chemotherapy Esophageal squamous cell carcinoma (ESCC) remains a major health challenge, with cisplatin (CDDP) being the primary chemotherapy drug, albeit accompanied by resistance development over time.
Advances in the Interaction between Food-Derived Nanoparticles and the Intestinal Barrier
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Advances in the Interaction between Food-Derived Nanoparticles and the Intestinal Barrier
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Agric. Food Chem. 2024, XXXX, XXX This article has not yet been cited by other publications.
Farm Animal Welfare Is a Field of Interest in China: A Bibliometric Analysis Based on CiteSpace
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by 1, 1, 1 and 1,2,* 1 College of Economics and Management, Northeast Agricultural University, Harbin 150030, China 2 Development Research Center of Modern Agriculture, Northeast Agricultural University, Harbin 150030, China * Author to whom correspondence should be addressed.
Study on the Accumulation of Heavy Metals in Different Soil-Crop Systems and Ecological Risk Assessment: A Case Study of Jiao River Basin
4. Conclusions Based on our study, certain conclusions were drawn as follows: Soils in JRB are short of HM sources. The average concentrations of HMs in the soil followed the order: Zn > Cr > Ni > Pb > Cu > As > Cd > Hg, similar to that of the other traditional agricultural growing regions in China and BGV, indicating that the disturbance of large-scale agricultural production on soil HMs is acceptable without external pollution sources.
Mechanical properties, thermal stability, and mechanism of main‐chain polybenzoxazine composites fabricated based on multi‐scale effects and surface functionalization of graphene oxide nanosheets
Polybenzoxazine (PBZ) has been recognized as a potential substitute for traditional phenolic resin. However, poor flexibility and low heat resistance limited obviously the application of PBZ. Herein, graphene oxide (GO) nanosheet and its amino-rich derivatives (fGO-g-SiO ) with multi-scale surfaces were designed, synthesized and incorporated into main-chain PBZ through in-situ polymerization to fabricate PBZ composites.
Neferine protected cardiomyocytes against hypoxia/oxygenation injury through SIRT1/Nrf2/HO‐1 signaling
DATA AVAILABILITY STATEMENT The analyzed data sets generated during the study are available from the corresponding author upon reasonable request.
Precision Livestock Farming Research: A Global Scientometric Review
1. Introduction The livestock industry serves as the foundation of the agricultural economy and constitutes the primary source of animal-derived product consumption. The growing demand for these products has led to a significant expansion in the scale of livestock breeding. However, traditional management practices that rely on farmers’ observations, judgment, and experience alone may not fulfill the requirements of modern large-scale livestock farming.
Occurrence of N‐nitrosodimethylamine in roasted Alaska pollock fillets during processing and storage and preliminary cancer risk assessment
Abstract BACKGROUND Dried and salt-fermented fish products are important sources of N-nitrosodimethylamine (NDMA) exposure for human. As a potent carcinogen, NDMA was frequently detected in roasted Alaska pollock fillet products (RPFs) which is among the most common fish products in China.
Super‐Stretchable, Anti‐Freezing, Anti‐Drying Organogel Ionic Conductor for Multi‐Mode Flexible Electronics
Abstract Due to their intrinsic flexibility, tunable conductivity, multiple stimulus-response, and self-healing ability, ionic conductive hydrogels have drawn significant attention in flexible/wearable electronics. However, challenges remain because traditional hydrogels inevitably faced the problems of losing flexibility and conductivity because of the inner water loss when exposed to the ambient environment.
Neural Network-Based Robust Bipartite Consensus Tracking Control of Multi-Agent System with Compound Uncertainties and Actuator Faults
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Robust Cooperative Control of UAV Swarms for Dual-Camp Divergent Tracking of a Heterogeneous Target
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Event-Trigger-Based Finite-Time Privacy-Preserving Formation Control for Multi-UAV System
Abstract : Privacy-preserving has been crucial technique of multi-UAV systems, including cooperative detection, cooperative penetration and strike. Unprocessed interactive information poses a serious privacy threat to UAV swarm collaborative tasks.
Atomic‐Level Regulation of Cobalt Single‐Atom Nanozymes: Engineering High‐Efficiency Catalase Mimics
Graphical Abstract A correlation between the atomic structures of Co single-atom nanozymes and their catalase-like performance is established by both computational screening and experimental design. A strategy is elucidated for atomic-level regulation of Co single-atom nanozymes operating as catalase mimics. Abstract Nanozymes aim to mimic the highly evolved active centers of natural enzymes.
Effects of Exogenous Auxin on Mesocotyl Elongation of Sorghum
1. Introduction Sorghum (Sorghum bicolor L. Moench) is an important food, feed, fiber, and biofuel crop worldwide. It provides nutrients and calories for much of the world’s population. “Early development” is a term used to describe plants that can grow fast at an early stage. The early development varieties normally have good competitiveness with weeds and could effectively improve nutrient use efficiency.
A Hybrid Piezoelectric and Electromagnetic Broadband Harvester with Double Cantilever Beams
4. Experimental Results and Discussion The experimental system consists of an oscilloscope, a signal generator, a power amplifier, a vibration exciter, and the proposed HPEBH (). The HPEBH parameters, motion parameters, and optimal load resistance are the same as those in the simulation. Two acrylic plates are attached to the vibration table of the vibration exciter, and the electromagnetic induction coil is sandwiched between the two acrylic plates.
Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing
Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing The process of wound healing is often accompanied by bacterial infection, which is a serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the resistance of bacteria and makes the therapeutic effect gradually deteriorate.
Molecular phylogeny and species delimitation of the genus Tonkinacris (Orthoptera, Acrididae, Melanoplinae) from China
Loading metrics Open Access Peer-reviewed Research Article Haojie Wang , Bing Jiang , Jingxiao Gu, Tao Wei, Liliang Lin, Yuan Huang, Dan Liang , Jianhua Huang Haojie Wang, Bing Jiang, Jingxiao Gu, Tao Wei, Liliang Lin, Yuan Huang, Dan Liang, Jianhua Huang Published: April 13, 2021 https://doi.org/10.1371/journal.pone.0249431 Figures Abstract Tonkinacris is a small group in Acrididae.
Phylogeny and species delimitation of the genus Longgenacris and Fruhstorferiola viridifemorata species group (Orthoptera: Acrididae: Melanoplinae) based on molecular evidence
Loading metrics Open Access Peer-reviewed Research Article Jingxiao Gu , Bing Jiang , Haojie Wang, Tao Wei, Liliang Lin, Yuan Huang, Jianhua Huang Jingxiao Gu, Bing Jiang, Haojie Wang, Tao Wei, Liliang Lin, Yuan Huang, Jianhua Huang Published: August 26, 2020 https://doi.org/10.1371/journal.pone.0237882 Figures Abstract Phylogenetic positions of the genus Longgenacris and one of its members, i.e. L. rufiantennus are controversial. The species boundaries within both of L.
Wideband and polarization-insensitive metamaterial absorber with loading lumped resistors
Han Xiong, Tian Bin Long, Ting Shi, Bing Xuan Jiang, and Jun Tao Zhang Author Affiliations Han Xiong,1,2,3,* Tian Bin Long,1 Ting Shi,1 Bing Xuan Jiang,1 and Jun Tao Zhang1 1School of Microelectronics and Communication Engineering, Chongqing University, Chongqing 400044, China 2State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University, Chongqing 400044, China 3State Key Laboratory of Millimeter Waves, Southeast University, Nanjing 211189,...
Anionic P-substitution toward ternary Ni-S-P nanoparticles immobilized graphene with ultrahigh rate and long cycle life for hybrid supercapacitors
Anionic P-substitution toward ternary Ni-S-P nanoparticles immobilized graphene with ultrahigh rate and long cycle life for hybrid supercapacitors Bing Jiang, Xiaohan Ban, Qian Wang, Kui Cheng, Kai Zhu, Ke Ye, Guiling Wang, Dianxue Cao and Jun Yan Abstract Designing and exploring earth-abundant but high-performance electrode materials are of crucial significance for the future large-scale development of supercapacitors.
Integrated evaluation of hardware and software interfaces for automotive human-machine interaction
Record: found Abstract: found Article: found Is Open Access Author(s): , , Publication date (Electronic): Keywords: , , , , , , , , , , , , , , There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta‐analysis
Original Article Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta‐analysis Bing Jiang Corresponding Author E-mail address: drjiangb@csu.edu.cn Department of Ophthalmology in the Second Xiangya Hospital, Central South University, Changsha, China Hunan Clinical Research Center of Ophthalmic Disease, Changsha, China Correspondence: Bing Jiang E‐mail address: drjiangb@csu.edu.cn Search for more papers by...
Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta‐analysis
Original Article Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta‐analysis Bing Jiang Corresponding Author E-mail address: drjiangb@csu.edu.cn Department of Ophthalmology in the Second Xiangya Hospital, Central South University, Changsha, China Hunan Clinical Research Center of Ophthalmic Disease, Changsha, China Search for more papers by this author Author contributions: XZ: Study concept and design;...
Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes
1.Gao, L. et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat. Nanotechnol. 2, 577–583 (2007).2.Kotov, N. A. Inorganic nanoparticles as protein mimics. Science 330, 188–189 (2010).3.Fu, S. et al. Structural effect of Fe3O4 nanoparticles on peroxidase-like activity for cancer therapy. Colloids Surface B 154, 239 (2017).4.Dong, J. et al. Co3O4 nanoparticles with multi-enzyme activities and their application in immunohistochemical assay. ACS Appl. Mater.
Macrolide Synthesis trough Intramolecular Oxidative Cross-Coupling of Alkenes
AbstractA Rh(III)-catalyzed intramolecular oxidative cross-coupling between double bonds for the synthesis of macrolides is described. Under the optimized reaction conditions, the macrocycles containing diene moiety could be formed in reasonable yields and with excellent chemo- and stereoselectivities. This study provides an efficient method to synthesize macrocyclic compounds containing 1,3-conjugated diene structure.
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