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Articles by Feng Shi
Engineering at surface-interface triggered by single sites to regulate selectivity of CO 2 reduction
Abstract Rational catalyst design and reaction mechanism investigation guided by clarification of relationship between the active sites and elementary reaction steps at molecular level are challenging but essential in heterogeneous catalysis. Here we demonstrate the alteration of active sites on surface-interface by doping Ag-single atoms to Cu-crystal lattice of Cu/Al2O3, tuning the selectivity of CO2 reductive amination from N-methylation to N,N-dimethylation.
Unveiling Failure of Gold Nanoclusters and Stabilization Strategies in the Gold Nanocluster-Catalyzed TiO 2 -Based Photoelectrode Design for Water Splitting Reaction
1 Introduction Since Fujishima and Honda first demonstrated photoelectrochemical water splitting on single-crystal TiO2 in 1972 to generate hydrogen [1], semiconductor-driven water decomposition has been regarded as an attractive route to replace conventional energy pathways by using sunlight to produce hydrogen fuel. However, anatase TiO2, which is the most widely used photocatalyst, has a bandgap of about 3.2 eV.
Potassium-driven coordination of carbon and nitrogen metabolism to enhance cotton fiber development under limited drip irrigation conditions
Abstract Introduction: Cotton is the world’s dominant natural fiber crop, and its production in arid oasis systems is widely constrained by drought. Potassium supplementation can alleviate water-deficit damage in cotton. However, the core mechanism linking potassium signaling to fiber carbon–nitrogen coordination and cellulose biosynthesis remains uncharacterized fiber.
BrainSeg: a generalized framework for comprehensive multimodal brain tissue segmentation, parcellation, and lesion labeling
Abstract Precise brain segmentation is fundamental for quantitative neuroimaging analysis. However, most existing methods lack generalization across the human lifespan and diverse imaging modalities, limiting their utility for Comprehensive Brain Segmentation (CBS) (i.e., tissue segmentation, parcellation, and lesion labeling).
Catalytic asymmetric formal nucleophilic C2-substitution of indoles via C2-umpolung toward 2,3’-bisindole atropisomers
Abstract The electrophilic substitution of indoles represents the predominant functionalization strategy. However, due to the electron-rich nature of the indole scaffold, catalytic asymmetric nucleophilic substitution remains markedly underdeveloped—presenting significant synthetic challenges and standing in stark contrast to its well-established electrophilic counterpart.
Iron overload disrupts bone homeostasis via dual pathways: inducing ferroptosis of preosteoblastic cells and shaping a proinflammatory immune milieu
Abstract Iron overload is regarded as an independent risk factor for osteoporosis, yet the underlying molecular mechanisms remain incompletely understood. In this study, we systematically investigated the impact of iron overload on bone homeostasis using a combination of in vivo and in vitro models. An iron overload rat model was established, and investigations were complemented by cellular assays utilizing mouse embryonic osteoblast precursor cells (MC3T3-E1) and macrophages.
The Complex Nature of the Vintage Violin Market and Its Luthiers: An Economic History (16th-21st Century)
The violin was created in northern Italy during the 16th century and became an important contributor to classical music. In this article, we examine the influence network associated with vintage violins (those made from 1590 to 1875) and their market (from 1590 to 2022). Our focus is on violins attributed to the top 30 violin makers (luthiers); their rank is determined by the highest transaction price ever received for one of their violins.
Solar Spectrum Splitting for Photovoltaic Applications
You are already at the latest version Photovoltaic (PV) systems are fundamentally limited by spectral mismatch between the solar spectrum and semiconductor band gaps, resulting in thermalization and transmission losses that reduce overall efficiency. This paper presents a critical review of spectral management approaches, focusing on solar spectrum splitting as a means to improve energy conversion.
Editorial: Advances in medical imaging for precision diagnostic and therapeutic applications in digestive diseases
Gastroenterology is undergoing a profound transformation, propelled by rapid advances in medical imaging. From multimodal techniques to artificial intelligence (AI)-driven diagnostics, the integration of innovative imaging technologies into clinical practice is redefining how digestive diseases are detected, characterized, and managed (1–7).
Scandinavian pattern and temperature changes shape European summer droughts over the past millennium
Abstract Recent decades have seen pronounced changes in European hydroclimate, including widespread summer drying, yet its spatiotemporal variability and underlying drivers remain uncertain. Here we present the European Last Millennial Data Assimilation (EULMDA), a new reconstruction of European hydroclimate and its main drivers covering the past millennium. EULMDA integrates five Earth System Model simulations with over one hundred moisture and temperature sensitive tree-ring records.
Global, regional and national cancer burden and trends of middle-aged and older populations: a GBD 2021-based analysis, prediction and prevention
Abstract Background: Middle-aged and older adults (MAOs; defined as individuals aged ≥40 years) account for the global cancer burden, contributing to 70–80% of cases. Characterizing cancer profiles in this demographic is essential for developing targeted prevention and treatment strategies to mitigate global impacts.
Pacific and Atlantic teleconnections reduce uncertainty in multidecadal projections of the South American Summer Monsoon
Abstract Reliable projections of the South American Summer Monsoon (SASM) are critical for managing regional hydroclimatic risks, yet remain highly uncertain due to internal climate variability. Here, we reconstruct a robust historical SASM index ensemble from 1850 CE onward by integrating high-resolution paleoclimate proxies (tree rings and ice cores), historical documents, and instrumental observations.
Real-world unified denoising for multi-organ fast MRI: a large-scale prospective validation
Abstract Lengthy acquisition time remains a key bottleneck for the widespread use of MRI in clinics. While accelerated MRI can reduce scan duration, it often introduces increased noise, compromising image quality and diagnostic reliability. In this study, we present a unified deep learning-based denoising model for multi-organ accelerated MRI, designed to operate directly on reconstructed images from commercial MRI systems.
Prediction of Recurrence-Free Survival in Patients with Gastrointestinal Stromal Tumors via Mixed CT Radiomics-Postoperative Pathology Models
Abbreviations GISTs (gastrointestinal stromal tumors) RFS (recurrence-free survival) ROC (receiver operating characteristic) AUC (area under the curve) CI (confidence interval) C-index (consistency index) ICC (intraclass correlation coefficient) LASSO (least absolute shrinkage and selection operator) ROI (region of interest) Key Words Gastrointestinal stromal tumors Recurrence-free survival Prediction Radiomics CT Get full text access Log in, subscribe or purchase for full access.
Frontiers | Time-resolved transcriptomic analysis reveals key regulatory genes and auxin-responsive networks underlying axillary bud branching in Hippophae rhamnoides
Abstract The development of axillary buds into branches fundamentally shapes plant architecture, yet how this process is transcriptionally coordinated across developmental stages in woody perennials remains incompletely understood.
ESRGAN-LS: super-resolution reconstruction of multi-scale defects in aerospace thermal barrier coatings via attention enhancement and dynamic feature optimization
Performance breakthroughs and safety assurance in flight equipment remain pivotal drivers of technological advancement, with every smooth flight relying on the stable output of core propulsion systems and the reliable operation of critical components. As the key protective system for hot-end components in aeroengines, thermal barrier coatings (TBCs) are prone to multi-scale defects under extremely high-temperature and high-pressure operating conditions.
Applications of Plant Lectins in Detection and Targeted Therapy of Urological Cancers
Back to Journals » Drug Design, Development and Therapy » Volume 20 Authors Long Z , Li Q, Shi F, Li F, Zang J Received 8 January 2026 Accepted for publication 22 March 2026 Published 1 April 2026 Volume 2026:20 594521 DOI https://doi.org/10.2147/DDDT.S594521 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Yan Zhu Zhihao Long,1,2 Qiwen Li,2 Feng Shi,1 Fengqian Li,2 Jing Zang2 1School of Pharmacy, Jiangsu...
The value of machine learning models in predicting lung metastasis in papillary thyroid carcinoma
Abstract Objective: To construct a machine learning (ML) model to predict the risk of lung metastasis in papillary thyroid carcinoma (PTC). Methods: This retrospective study included 681 PTC patients who received radioactive iodine (RAI) treatment for the first time. Among them, 71 patients were diagnosed with lung metastasis (10.4%).
A New Compensated Rectifier for Wireless Energy Harvesting System With Low Start‐Up Voltage and High Sensitivity
Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References 1 WiFi-Alliance, “ Wi-Fi Alliance Publishes 2018 Wi-Fi Predictions,” (2018), https://www.wi-fi.org/news-events/newsroom/wi-fi-alliance-publishes-2018-wi-fi-predictions.
Multicenter study on the versatility and adoption of AI-driven automated radiotherapy planning across cancer types - Nature Communications
Abstract Deep learning (DL) -based automated treatment planning (ATP) shows significant promise in streamlining radiotherapy workflow and reducing variability in plan quality. However, it often lacks the flexibility needed for achieving individualized trade-offs in real-world practice. Herein, we propose a hybrid strategy by integrating DL-based dose prediction with clinical-goal-guided inverse optimization to generate directly deliverable plans within five minutes.
Volcanic eruptions disrupt ENSO teleconnections with land summer temperature - Nature Communications
Abstract The El Niño–Southern Oscillation (ENSO) is a key ocean-atmospheric mode that affects global weather and climate through atmospheric teleconnections. It remains unclear how robust and stable ENSO teleconnection patterns are under external perturbations. Here, we use observations to demonstrate that volcanic eruptions disrupt ENSO teleconnections with land surface air temperature in boreal summer across the globe.
Intelligent diagnosis of ossicular chain malformations on CT: development and clinical efficacy of a cascaded AI framework
Abstract Objective: The aim of this study was to develop and validate a cascaded artificial intelligence (AI) framework using a segmentation–discrimination strategy for automated detection of ossicular chain malformations (OCM) on computed tomography scans. Methods: Patients diagnosed with OCM between January 2009 and January 2023, along with healthy controls, were retrospectively enrolled. A coarse-to-fine nnU-Net framework was applied for automated segmentation of the auditory ossicles.
Three‐Channel Electron Engineered Fe‐88A@CeO2/CDs Nanozyme with Enhanced Oxidase‐Like Activity for Efficient Biomimetic Catalysis
1 Introduction Staphylococcus enterotoxin B (SEB) poisoning poses a significant threat to public health and safety.[1, 2] Consequently, the rapid and accurate identification and detection of SEB are of paramount importance.
Analysis of the impact of smoothing on residual error accuracy and high-precision figuring method based on spatial filtering in magnetorheological finishing for high-gradient CPP components
The large-aperture CPP is widely used in inertial confinement fusion systems. It is a key diffractive optical element to achieve beam shaping and smoothing. Successful ignition fusion has placed high requirements on its surface accuracy and gradient. The MRF used to imprint large-aperture CPP will introduce mid-spatial frequency errors, which will seriously affect the performance of CPP and the further convergence of subsequent residual errors. Smooth is often used to control it.
Polymeric Nanocarriers for Targeted Therapy: Current Advances and Future Perspectives
This version is not peer-reviewed. You are already at the latest version Polymeric nanomedicine has emerged as a versatile and transformative platform for the delivery of therapeutic agents, offering controlled release, enhanced stability, and targeted delivery across a broad spectrum of medical applications.
Glymphatic-mediated Pathway Pinking Neurovascular Dysfunction to Cognitive-sleep Impairment in Cerebral Small Vessel Disease
Abbreviations CSVD (cerebral small vessel disease) CSVD-MCI (cerebral small vessel disease-related mild cognitive impairment) CSVD-NC (cerebral small vessel disease with normal cognition) CSF (cerebrospinal fluid) CPV (choroid plexus volume) DTI-ALPS (diffusion tensor image along the perivascular space) NVC (neurovascular coupling) PVS (perivascular space) VWC (voxel-wise concordance) Key Words Cerebral small vessel disease Cognitive impairment Diffusion Tensor Image Analysis ALong the...
Adaptive multi-scale attention networks fusion in YOLOv12-LSE: a lightweight framework for efficient and robust underwater object detection
Underwater object detection is difficult for existing models to balance accuracy and efficiency due to problems such as complex optical interference, blurred features of small targets, and the limited computing power of edge devices.
Multiparameter MRI-based automatic segmentation and diagnostic models for the differentiation of intracranial solitary fibrous tumors and meningiomas
ABSTARCT Background Intracranial solitary fibrous tumors (SFTs) and meningiomas are meningeal tumors with different malignancy levels and prognoses. Their similar imaging features make preoperative differentiation difficult, resulting in high misdiagnosis rates. Thus, accurately distinguishing SFTs from meningiomas preoperatively is vital for surgical planning and treatment strategies.
Peripheral TNF-α and CD8
Back to Journals » Breast Cancer: Targets and Therapy » Volume 17 Authors Wu J, Ou X, Yuan K, Shi F , Zhou Q, Lyu S, Li Y, Zhao Y , Cao Y, Sun J , Song Q Received 11 May 2025 Accepted for publication 16 July 2025 Published 19 July 2025 Volume 2025:17 Pages 627—637 DOI https://doi.org/10.2147/BCTT.S532688 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Pranela Rameshwar Jiangping Wu,1,* Xin Ou,1,*...
Experimental study on screening and optimization of CO2 huff-n-puff parameters based on nuclear magnetic resonance online analysis technology: a case study of Jimsar shale oil reservoir in Xinjiang, China
To tackle the challenges of unstable production and low recovery rates in the Lucaogou shale oil reservoir of the Jimsar sag in Xinjiang, laboratory CO huff-n-puff experiments were conducted using five lithologically distinct core samples from key development layers. Using high-temperature and high-pressure NMR scanning, this study explores recovery variations across lithologies and the impacts of CO injection volume, soaking time, and huff-n-puff cycles.
Study on the preparation of sterile noble metal nanoparticles and hydrotalcite layered nanoparticles by innovative high pressure sterilization method - Scientific Reports
Abstract We have developed an innovative nanoparticle preparation technique. It utilised a high-pressure steam sterilisation pot as the reaction equipment, simplifying biomedical nanoparticle synthesis and sterilisation processes. Gold nanoparticles (AuNPs), silver nanoparticles (AgNPs), and two types of hydrotalcite-layered nanoparticles (LDHs) were prepared successfully.
Recent Advances in Enzyme‐Mediated Rolling Circle Replication Technology Empowering Virus Detection
References 1 ; ; ; ; ; ; ; ; Advanced Point-of-Care Testing Technologies for Human Acute Respiratory Virus Detection. Adv. Mater. 2022, 34, 2103646. 2 ; ; ; Long COVID: major findings, mechanisms and recommendations. Nat. Rev. Microbiol. 2023, 21, 133–146. 3 Overview of thermostable DNA polymerases for classical PCR applications: from molecular and biochemical fundamentals to commercial systems. Appl. Microbiol. Biotechnol. 2013, 97, 10243–10254.
Rapid degradation of microplastics by catalyst-free gliding arc plasmatron†
Rapid degradation of microplastics by catalyst-free gliding arc plasmatron† A gliding arc plasmatron (GAP) was proposed for efficient degradation of mixed microplastics (MPs) under simplified and adaptable conditions. Complete degradation of MPs can be achieved within 2–4 minutes, with non-hazardous CO₂ as nearly the only gas product. The catalyst-free GAP system, with its simplicity and compatibility with distributed renewable energy supply, offers a sustainable solution for MPs treatment.
Selection of Optimal Intensity Measures and Seismic Fragility Analysis of Prefabricated Rectangular Subway Stations
3.4. Structural Damage Assessment Analysis In accordance with the IDA methodology, this study systematically examined and compared the damage progression patterns exhibited by prefabricated subway station structures under three distinct PGA levels of the seismic motion listed in Table 6. The selected PGA levels are 0.1 g, 0.6 g, and 1.2 g.
Synthesis of N,N'‐Bisindoles via Gold‐Catalyzed Formal (4+1) Cycloaddition
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Diagnosis and Severity Assessment of COPD Based on Machine Learning of
He Sui,1,* Zhanhao Mo,1,* Ying Wei,2 Feng Shi,2 Kailiang Cheng,1 Lin Liu1 1China-Japan Union Hospital of Jilin University, Changchun, People’s Republic of China; 2Shanghai United Imaging Intelligence Co., Ltd., Shanghai, People’s Republic of China *These authors contributed equally to this work Correspondence: Kailiang Cheng, Department of Radiology, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Erdao District, Changchun, People’s Republic of China, Email...
Numerical Simulation of CO2 Immiscible Displacement Based on Three-Dimensional Pore Structure
1. Introduction Oil and gas resources are becoming increasingly scarce, while global demand continues to rise. Low-permeability reservoirs, such as shale, tight sandstone, and coal seams, are characterized by low porosity, which poses significant challenges to efficient oil displacement and recovery. These limitations result in low recovery efficiency, underscoring the urgent need for research aimed at improving oil recovery in tight reservoirs.
Synthesis of Indole‐Fused Chromane‐Based Spirooxindoles via Brønsted Acid‐Catalyzed Regioselective [5+1] Annulation
Conflict of Interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Synthesis of Indole‐Fused Chromane‐Based Spirooxindoles via Brønsted Acid‐Catalyzed Regioselective [5+1] Annulation
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Non-Enzymatic Electrochemical Glucose Sensors Based on Metal Oxides and Sulfides: Recent Progress and Perspectives
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Co-catalysis of Al2O3-supported Ni nanoparticles and VOx in propane dehydrogenation
Co-catalysis of Al2O3-supported Ni nanoparticles and VOx in propane dehydrogenation The catalytic activity of NiV2Ox/Al2O3 for propane dehydrogenation (PDH) at 500 oC exhibited 2-5 times improved compared with their monometallic counterparts, primarily attributed to the synergistic effect of Ni nanoparticles (NPs) and VOx, which not only promotes the desorption of propylene but also promotes the generation and desorption of H2, significantly improving the catalytic performance.
Design of High‐Sensitivity Cold‐Start Circuit for Wireless Energy Harvesting With Low Start‐Up Voltage
References 1 WiFi-Alliance. (Jan. 2018). Wi-Fi Alliance Publishes 2018 Wi-Fi Predictions. [Online]. Available: https://www.wi-fi.org/news-events/newsroom/wi-fi-alliance-publishes-2018-wi-fi-predictions. 2 Texas Instruments. (May 2005). ISM-Band and Short Range Device Regulatory Compliance Overview. [Online]. Available: http://www.ti.com/lit/an/swra048/swra048.pdf.
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