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Articles by Feng Wen
Geometric and concavity characteristics as diagnostic markers for differentiating nAMD-related MNV from pachychoroid neovascularisation
Abstract To investigate morphometric differences in macular neovascularisation (MNV) outer contours between neovascular age-related macular degeneration (nAMD) and pachychoroid neovasculopathy (PNV) using quantitative optical coherence tomography angiography (OCTA) analysis. This retrospective cross-sectional study enrolled treatment-naïve patients with newly diagnosed MNV, classified into nAMD and PNV groups.
Value of preoperative peripheral blood inflammation markers in predicting prognosis after radical gastric cancer surgery
Abstract We aimed to systematically investigate the association between ten preoperative peripheral blood inflammatory markers and the clinicopathologic characteristics and outcomes of gastric cancer (GC) and develop a prediction model for overall survival (OS) based on these markers. We conducted retrospective analyses of the clinicopathological data of 921 patients with gastric cancer who underwent radical gastrectomy, adjusting baseline characteristics using propensity score matching (PSM).
Development and benchmark validation of PubChat for PubMed-grounded multilingual biomedical literature retrieval
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Abstract The rapid growth of biomedical literature has rendered traditional systematic reviews unsustainable. Although large language models (LLMs) offer automation potential, citation fabrication and unreliable evidence discrimination remain critical barriers.
By Xuenan Zhuang, Dan Cao, Ruoyu Chen, Yuxuan Wu, Qianjin Feng, Philip Guo, Gianvito Urgese, Shenghao Fu, Kun-Yu Lin, Zhijun Lin, Zedan Zhang, Ze Yuan, Enrico Borrelli, Feng Wen, Jiaxin Pu, Mengjie Li, Anyi Liang, Zhicong Xu, Zikang Xu, Danling Huang, Taozheng Li, Jiayi Huang, Jing Li, Xinyu Wang, Qi Chen, Peibo Chen, Liang Zhang, Jinyun Jiang, Ingrid Manguera Hojas, Mi Gui, Yinzhou Zhong, Huanzi Lu
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Nature
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Polarization-Insensitive VO 2 /Graphene/Diamond Heterostructure Metasurface With Dynamic Broadband/Narrowband Tunability
Boning Wen and Shaowei Zhang contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request. References 1, , , et al., “Multifunctional Terahertz Metamaterials Device Based on a Dual-Tunable Structure Incorporating Graphene and Vanadium Oxide,” Nanoscale Advances 7, no.
A symbiotic skin hydrogel interface enabled by flexible hydrogel network with embedded enhancement structure
Abstract Wearable electrophysiological monitoring based on hydrogel electrodes is pivotal for decoding the body’s “electrical language”, yet fundamentally hampered by the unstable mechano-electrical interface between flexible electrodes and the skin caused by dehydration and poor breathability. Here, we demonstrate a symbiotic interface between an embedded-interfacial enhanced breathable conductive hydrogel network (BCHN) and skin for high-fidelity long-term electrophysiological monitoring.
Single cell spatial transcriptomics track the evolutionary hierarchy and microenvironment remodeling during breast carcinoma invasion
Abstract The progression from ductal carcinoma in situ (DCIS) to invasive breast carcinoma (IBC) critically determines patient outcomes, yet its mechanisms remain incompletely understood. Integrating single-cell RNA sequencing, spatial transcriptomics, and genomics across 28 patients with synchronous DCIS and IBC, we delineate the spatial-molecular hierarchy of this transition.
Indocyanine green angiography and machine learning analysis determine topographic distribution of peripheral hard drusen in a Chinese cohort
Abstract Hard drusen appear as hyperfluorescent dots on indocyanine green angiography (ICGA) due to their high phospholipid content. This study aims to explore the distribution of peripheral hard drusen across age groups and retinal regions, and their correlation with macular pathology including hard drusen, soft drusen, and progression to neovascular age-related macular degeneration (nAMD). A hospital-based retrospective study was conducted at Zhongshan Ophthalmic Center.
Adjuvant Chemoradiotherapy or Chemotherapy After D2 Gastrectomy in Gastric Cancer : A Randomized Clinical Trial
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Adjuvant Chemoradiotherapy or Chemotherapy After D2 Gastrectomy in Gastric Cancer: A Randomized Clinical Trial Supplement 1. Supplement 2. eTable 1. Multivariable Cox Proportional Hazards Regression Analyses for Disease-Free Survival and Overall Survival eTable 2. All Grade and Maximum Grade Adverse Events eFigure 1. Trial Design and Treatment Schema eFigure 2. Per-Protocol Disease-Free Survival eFigure 3. Per-Protocol Overall Survival eFigure 4. Subgroup Analyses of Overall Survival Supplement 3.
By Xin Wang, Ouying Yan, Jitao Zhou, Feng Wen, Yali Shen, Zhiping Li, Qiu Li, Wenling Wang, Xiaohong Cai, Shisheng Tan, Zi Wang, Qing Qiao, Dan Cao, Meng Qiu, Jiyan Liu, Hongfeng Gou, Ming Liu Verified, Cheng Yi, Yu Yang, Qing Zhu, Deyun Luo, Yaqin Zhao, Ye Chen, Shang Wang, Qiaoli Wang, Ke Cheng, Min Ren, Xin Chang Liu, Feng Xu, Feng Bi
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JAMA Network
Verified
A comparative analysis of traditional Chinese medicine health management services in Urban versus rural areas of Chongqing: implications for policy and practice
Abstract Background: Traditional Chinese medicine (TCM) health management plays an increasingly important role in China’s public health system, particularly in community-based and geriatric care. However, significant disparities between urban and rural areas have emerged during the implementation of related policies.
Epidemiology and risk factors for corneal blindness in China: a multicentre retrospective study of 15,937 inpatients - Eye
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Abstract To describe the demographic and clinical characteristics of inpatients with corneal blindness in China and identify independent risk factors. This multicentre, retrospective, observational study was conducted by 16 clinical centres in 15 provincial-level administrative regions across China. Inpatients discharged with a primary diagnosis of corneal disease between January 1, 2019, and December 31, 2021, were included.
By He Xie, Xiaoyu Zhang, Kexin Tang, Kaisheng Wang, Chenxi Wang, Ruifen Wei, Jie Wu, Hai Liu, Qi Zhang, Baihua Chen, Jinsong Xue, Huiping Li, Feng Wen, He Dong, Tao Lin Sun, Jizhong Yang, Limin Chen, Shaozhen Zhao, Zhirong Liu, Pengcheng Wu, Yingnan Xu, Wei Qiang, Qi Xie, Yuping Han, Linying Huang, Hui Liu, Man Yu, Chenhang Ding, Gang Chen, Wei Chen
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Nature
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Posterior Auricular Artery as a Landmark to the Facial Nerve During Parotidectomy: A Cadaver Study
Conflicts of Interest The authors declare no conflicts of interest. References 1 and , “Salivary Gland Neoplasms: Future Perspectives,” Advances in Oto-Rhino-Laryngology 78 (2016): 198–199. 2, , , , and , “FN Morbidity Following Surgery for Benign Parotid Tumours,” Journal of the College of Physicians and Surgeons–Pakistan 24, no. 8 (2014): 569–572.
Yuying Ji - OCT News
October 1, 2022 | Ophthalmology | Sun Yat-Sen University Purpose: The retina could serve as a window of neuroinflammation, but the in vivo changes in macrophage-like cell (MLC), such as microglia, in acute ischemic retinal stroke remain unclear. Thus, the current study aimed to investigate the in vivo changes in MLC characterized by en face optical coherence tomography (OCT) after acute ischemic retinal stroke.
Lan Mi - OCT News
November 15, 2021 | Ophthalmology | South China Normal University, Sun Yat-Sen University Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD). Methods: A total of 380 drusen in 45 eyes in 35 patients with the intermediate drusen were longitudinally followed up every 6 months by SD-OCT for a period of 24 months.
A Flexible Hydrovoltaic Device with Strain‐Induced Ion Selectivity
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202508734-sup-0001-SuppMat.docx38.1 MB Supporting Information References 1, , , , , , , , , , Adv. Mater. 2024, 36, 2310260. 2, , , , , , , , , , , Adv. Mater. 2023, 35, 2304099. 3, , , , , J. Phys. Chem. C 2012, 116, 8672. 4, , , , , , , , , , , Chem. Soc. Rev. 2022, 51, 4902. 5, , , , ACS Nano 2024, 18, 23912. 6, , , , , , , , , Angew. Chem. 2020, 132, 10706.
Targeting mitochondrial complex I of CD177+ neutrophils alleviates lung ischemia-reperfusion injury
Keywords lung ischemia-reperfusion injury neutrophil CD177 oxidative phosphorylation mitochondrial complex I Introduction Primary graft dysfunction (PGD), a clinical manifestation of ischemia-reperfusion injury (IRI) following lung transplantation, affects approximately 15%–25% of recipients within the initial 72 h post-transplantation.1,2,3 It is the principal cause of short-term mortality, premature graft failure, and chronic rejection.
Molecular Dynamics Study on the Lubrication Mechanism of the Phytic Acid/Copper Interface Under Loading Condition
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Evolving H5N1 receptor specificity
Information & Authors Information Published In Science Volume 387 | Issue 6738 7 March 2025 Copyright Copyright © 2025 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Article versions Submission history Published in print: 7 March 2025 Permissions Request permissions for this article.
Hydrogel‐Based Moisture Electric Generator with High Output Performance Induced by Proton Hopping
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202500186-sup-0001-SuppMat.docx21.2 MB Supporting Information References 1a) , , , , , Adv. Mater. 2024, 36, 2209661; b) , , , , , , , , Adv. Mater. 2020, 32, 2003722; c) , , , , , , , , , Energy Environ. Sci. 2022, 15, 2601; d) , , , , , , , , , Angew. Chem., Int. Ed. 2020, 59, 10619. 2a) , , , , , , , eScience 2022, 2, 32; b) , , , , , , , , , Nat. Water 2024, 2, 93; c) , , , , , , , , , Adv.
A Novel Aphis gossypii Killing Surfactin Produced by Bacillus australimaris TRM82479 of Taklamakan Desert Origin
Submitted: 07 January 2025 You are already at the latest version The cotton aphid Aphis gossypii poses a global, serious threat to cotton yield and quality. Although chemical pesticides are effective, pollution and resistance are increasingly prominent, making development of new biopesticides a priority in the context of green agricultural development. Given that reports on the activity of surfactins against A.
Development and antibacterial evaluation of a dopamine-modified curcumin@zinc-based organic framework
Development and antibacterial evaluation of a dopamine-modified curcumin@zinc-based organic framework† Antibiotics are crucial for treating and preventing bacterial infections. However, the widespread use of antibiotics has led to serious antibiotic resistance issues. To address the growing threat of antibiotic-resistant bacterial infections, we designed and synthesized an antibacterial composite material, CCM@ZIF-8@PDA, through a one-pot method and surface modification strategy.
Microbial Community Structure in the Taklimakan Desert: The Importance of Nutrient Levels in Medium and Culture Methods
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Microstructure and Mechanical Properties of the Powder Metallurgy Nb-16Si-24Ti-2Al-2Cr Alloy
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Terahertz dynamic multiband perfect absorber with a digital coding graphene-diamond metasurface
The monolayer graphene-based terahertz (THz) perfect absorber has made significant progress in switchable devices with diverse functionalities. However, existing methods for achieving switchability rely on either multilayered metasurface with complex configurations or complicated patterned metasurfaces. A switchable absorber that switches between n-band and m-band modes (n, m correspond to the number of resonance peaks) using tunable materials is also interesting but has not yet been mentioned.
Evidence for a causal relationship between immune cells and cutaneous melanoma: a Mendelian randomization study
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Letter: Risks of proton pump inhibitor treatment in cirrhotic patients
We read with great interest the recent multicentre retrospective cohort study by Yoon et al1 showing that the use of high-dose proton pump inhibitor (PPI) was independently associated with increased risks of mortality and cirrhotic complications including hepatic encephalopathy (HE), spontaneous bacterial peritonitis(SBP), hepatorenal syndrome and gastrointestinal bleeding (GIB). However, we have two concerns about this study.
Enhancing secure multi-group data sharing through integration of IPFS and hyperledger fabric
The Internet has revolutionized data access, making data sharing a ubiquitous aspect of daily life. However, sharing data over public networks exposes it to significant security risks, such as data error handing and tampering (Anwar et al., 2022). This has led to a major challenge in ensuring data integrity and verifiability. Trusted third parties play a crucial role in facilitating secure data sharing, as they can authenticate and reliably transmit data (Naz et al., 2019).
Optimized Tribological Performance of Nitrogen-Doped Diamond-like Carbon Films on NBR: Influence of Bias Voltage of DC Magnetron Sputtering
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Magneto-optical fiber-based orbital angular momentum mode converters
Orbital angular momentum (OAM) mode division multiplexing (MDM) systems can support large-capacity and high-speed rate information transmission, in which the OAM mode conversion devices play an important role.
Assessment of magnetic resonance imaging and histopathological changes in chordoid glioma: A retrospective analysis of 13 cases
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES 1, , , , , . Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol. 1998; 57(3): 283-290. 2, , , . Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. J Clin Pathol. 2007; 60(11): 1294-1295. 3, , , . Chordoid glioma: a case report of unusual location and neuroradiological characteristics. J Korean Neurosurg Soc. 2010; 48(1): 62-65.
Bladder sparing by short-course radiotherapy combined with toripalimab in high-risk/extremely high-risk non-muscle invasive bladder cancer (HOPE-04): study protocol for a single-arm, prospective, phase II trial
Bladder sparing by short-course radiotherapy combined with toripalimab in high-risk/extremely high-risk non-muscle invasive bladder cancer (HOPE-04): study protocol for a single-arm, prospective, phase II trial Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service.
Nanomaterials | Free Full-Text | Determining the Dependence of Single Nitrogen−Vacancy Center Light Extraction in Diamond Nanostructures on Emitter Positions with Finite−Difference Time−Domain Simulations
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Mode coupling in FM-EDFAs caused by fiber bending: theory and experiments
Refractive index perturbation caused by erbium-doped fiber (EDF) bending is inevitable in the fabrication of erbium-doped fiber amplifiers (EDFAs). The resulting mode coupling might bring about the deviation of theoretical results from experimental data. We present a theoretical model of FM-EDFAs with mode coupling due to fiber bending and carry out a proof-of-concept experiment by a 3.2-m-long EDF stretcher.
Conductive Hydrogel for Flexible Bioelectronic Device: Current Progress and Future Perspective
Conflict of Interest The authors declare no conflict of interest. References 1, , Science 2017, 356, 3627. 2, , , , , , , , , Chem. Soc. Rev. 2023, 52, 473. 3, , Nat. Rev. Mater. 2016, 1, 16071. 4, , , Chem. Soc. Rev. 2019, 48, 1642. 5, , , , , , , , , , Chem. Eng. J. 2020, 385, 123912. 6, Science 2012, 336, 1124. 7, , Nat. Rev. Mater. 2018, 3, 125. 8, , , Biotechnol. Bioeng. 1996, 50, 357. 9, , , , , , , , , Small 2022, 18, e2101518. 10, , , , , , , ACS Nano 2021, 15, 7765. 11, , , , , , Adv. Sci. 2017, 4, 1600190.
Construction Control and Monitoring Platform of a Large-Segment Steel Box Girder with Hoisting Installation
1. Introduction Bridge construction, as an important component of transportation infrastructure, has gained more and more attention with the development of large bridge spans; increased complexity of bridge structures; and growing awareness of driving safety and the gradual development of new materials, intelligent perception, and big data technology.
Experimental Study of Bridge Expansion Joint Damage Based on Natural Frequency
2.2. Experimental Process In a bridge, the center beam and support bar are first cracked and then gradually damaged. However, it is not easy to simulate this situation in the laboratory. In addition, it is essential to consider the different stages of damage to the expansion joints, especially at the beginning of the damage. Therefore, multiple damage scenarios need to be developed.
Subfoveal Focal Choroidal Excavation with Macular Vortex Vein
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欧洲专利制度简介
在全球化的竞争环境下，中国企业要想在国际市场中占据有利地位，就必须不断提高自身的创新能力和核心竞争力，同时也要重视自己的知识产权保护，统筹国内外市场建立完善的专利战略，为自己的国际经营活动提供法律保障。 欧洲是全球最大的经济体之一，也是中国企业的重要出口目的地和合作对象，因此在欧洲申请和维护专利对于中国企业具有重大的战略意义。一方面，这样可以有效地防止自己的技术成果被侵犯，维护自己的合法权益，避免因为专利纠纷而导致的经济损失和声誉受损。另一方面，这样也可以增强自己的市场竞争力和影响力，提升自己的品牌价值和信誉度，扩大自己的市场占有率和营收规模。除此之外，还可以促进自己的技术创新和转化，加强与欧洲的技术合作和交流，提高自己的国际地位和声望。 本文将对欧洲专利制度进行简要介绍，希望帮助中国企业更好地了解欧洲专利制度的运作和发展，以便为中国企业的技术创新和国际竞争提供更多的支持和保障。 一、欧洲专利制度的发展概述...
Hyperfluorescence of choroidal arteries in the peripheral fundus on late-phase ICGA - Eye
Abstract Aims To correlate the hyperfluorescent lines in the peripheral fundus on late-phase indocyanine green angiography (ICGA) to infrared and optical coherence tomography (OCT) findings. Methods This is a retrospective, cross-sectional study. Multimodal imaging data, including ICGA, fluorescein angiography, infrared imaging, and OCT were analyzed. The hyperfluorescent lines were categorized into 2 grades according to their extents.
Molecular Cloning and Characterization of WRKY12, A Pathogen Induced WRKY Transcription Factor from Akebia trifoliata
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Identification of a duck H9N2 influenza virus possessing tri-basic hemagglutinin cleavage sites genetically close to the human H9N2 isolates in China, 2022
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Microstructure and Strength Parameters of Cement-Stabilized Loess
3. Results and Discussion 3.1. Compaction Properties The standard test approach for laboratory soil compaction characteristics was used to perform compaction tests with normal effort. Trace cement in loess soil affected its usual Proctor compaction curves (Figure 5). The maximum dry unit weight decreased from 1.82 g/cm3 to 1.48 g/cm3 when the cement concentration was increased from 0% to 9% and the appropriate moisture level increased from 0.12% to 0.14%.
Frontiers | Intracoronary Imaging-Guided Rotational Atherectomy Combined with Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification-a Case Report
Feng wen Cui1, Yaliang Tong1, GuoHui Liu1, Wenqi Zhang1, Kun Liu1, Daoyuan Si1* and Yuquan He1* 1cardiology, China-Japan Union Hospital, Jilin University, China The final, formatted version of the article will be published soon. Receive an email when it is updated Background: Severe coronary artery calcification increases the difficulty of percutaneous coronary intervention procedures and impairs stent expansion.
Physics-model-based neural networks for inverse design of binary phase planar diffractive lenses
Abstract The inverse design approach has enabled the customized design of photonic devices with engineered functionalities through adopting various optimization algorithms. However, conventional optimization algorithms for inverse design encounter difficulties in multi-constrained problems due to the substantial time consumed in the random searching process.
The Study of Surface Structure and the Tribological Property of DLC-Modified NBR Elastomers Using DC-MS
Abstract : The DLC film was prepared on a nitrile rubber (NBR) elastomer by DC magnetron sputtering (DC-MS), and the sp3 ratio of the DLC film was adjusted by changing the negative bias voltage applied to the substrate. The microstructure, composition, and tribological properties of the DLC films deposited on NBR substrates were systematically investigated. The results reveal that the DLC film on the NBR surface can protect the NBR and reduce the surface roughness of the NBR.
Perovskite Tandem Solar Cell Technologies
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Transport Behavior of Methane Confined in Nanoscale Porous Media: Impact of Pore Evolution Characteristics
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Potential Threats to Human Health from Eurasian Avian-Like Swine Influenza A(H1N1) Virus and Its Reassortants
Since emerging in 2001, Eurasian avian-like (EA) swine influenza A(H1N1) virus has gradually become the predominant lineage and continues to circulate among pigs in China (1–3). Introduction of the 2009 pandemic H1N1 virus (pH1Na) among pigs has increased its reassortment with EA H1N1 swine influenza A viruses (IAVs), and several reassortant variants with the potential to infect humans have been detected in China (4–8).
Phase-preserving NALM regenerator with lower input power by optimizing the nonreciprocal phase shifter
Abstract We propose a new nonlinear amplifying loop mirror (NALM)-based phase-preserving amplitude regenerator (so-called NP-NALM) by introducing a nonreciprocal phase shifter to further improve the regeneration performance. The theoretical model of the NP-NALM structure and the amplitude regeneration and phase-preserving conditions are presented.
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