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Articles by Guoping Wang
Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial Key Points Question Does intravenous tenecteplase before endovascular thrombectomy improve outcomes in patients with basilar artery occlusion who present to thrombectomy-capable centers between 4.5 and 24 hours after stroke onset?
Reliability-aware query restoration for embedded real-time object detection in degraded underwater vision systems
Abstract Embedded underwater vision systems require real-time object detection that remains reliable in the face of turbidity, color attenuation, low contrast, weak boundaries, and cluttered backgrounds. In real-time detection transformer (RT-DETR)-style detectors, these degradations affect the ranking and selection of encoder candidates used to initialize decoder queries. This study proposes a degradation-aware query reliability restoration framework for RT-DETR, termed DQR-RTDETR.
Microbiota-gut-brain axis in autism spectrum disorder: integrating brain structure, function, and transcriptomics
Abstract Growing evidence indicates that disruption of the microbiota–gut–brain (MGB) axis is a key factor in autism spectrum disorder (ASD), affecting neurodevelopment, neural circuit function, and behavior. This review synthesizes multidisciplinary data to clarify mechanistic links between the MGB axis and ASD and to evaluate microbiota-targeted therapeutic strategies.
Structural and molecular substrates underlying functional dysconnectivity and cognitive impairment in neuronal intranuclear inclusion disease
ORIGINAL RESEARCH article Front. Behav. Neurosci., 03 July 2026 Sec.
Evaluation of the real-world safety of eptifibatide in the treatment of ARDS: results of a disproportionality analysis of FAERS data
Abstract Background: Acute respiratory distress syndrome (ARDS) is a clinical syndrome with an extremely high mortality rate, and antiplatelet therapy is an important treatment approach. Eptifibatide, a glycoprotein IIb/IIIa receptor inhibitor (GPI), is primarily used to treat acute coronary syndrome (ACS) and non-venous thromboembolic pulmonary embolism, as well as for antiplatelet therapy in conditions such as ARDS and septic shock.
Deep-subwavelength ultra-low and ultra-broadband acoustic-black-hole metamaterials - Nature Communications
Abstract Acoustic black holes (ABHs) offer broadband wave-manipulation capabilities beyond conventional acoustic metamaterials (AMs) but are fundamentally limited by compromised structural stiffness, high-precision machining requirements and high cut-on frequencies. Here, we break these limitations by adopting a power-law density-tailored composite, ρ-ABH.
Optimization design and performance analysis of a rotary vane magnetorheological damper for vehicle suspension based on NSGA-II
Ayuda Buscar en la ayuda Buscar en la ayuda Optimization design and performance analysis of a rotary vane magnetorheological damper for vehicle suspension based on NSGA-II Jiaqi Wang [1] ; Guoping Wang [1] ; Min Wei [1] ; Rilang Jiang [2] ; Zhuang Jin [1] ; Lingyun Wang [1] [1] National Key Laboratory of Complex Multibody System Dynamics, Nanjing University of Science and Technology, Nanjing, China [2] School of Mechanical Engineering, Zhejiang Sci-Tech University, Hangzhou, China...
Efficient Dynamics Modeling and Adaptive Tracking Control for a Rigid‐Flexible Manipulator
Vibration suppression and trajectory tracking are pivotal areas of current robotics research, significantly influencing the operational performance of flexible manipulators. This article proposes a novel dynamics modeling strategy for flexible manipulators based on the multi-body system transfer matrix method, which achieves comparable accuracy to the traditional Lagrange method while improving computational efficiency by approximately 35.5% and 35.9% in two representative cases, respectively.
Modelling and control of magnetorheological hydro-pneumatic suspension system based on multibody system transfer matrix method
Abstract A new type of magnetorheological (MR) hydro-pneumatic suspension (HPSP) system was proposed by introducing MR technology into traditional HPSP system to improve ride comfort and handling stability of vehicles. The dynamics model of MRHPSP system was established based on multibody system transfer matrix method (MSTMM), and an effective control method was designed. Firstly, the mechanical properties of the MR hydro-pneumatic (HP) spring were tested.
Diagonal Hessian Proxy for Efficient Elastic Simulation Using Peridynamics
IEEE transactions on visualization and computer graphics. 2024 Dec 12:PP. doi: 10.1109/TVCG.2024.3516480 Q14.72024 作者单位 +展开 作者单位 DOI: 10.1109/TVCG.2024.3516480 PMID: 40030524 摘要 翻译 Meshless simulation of elasticity is important for deformable simulation in computer graphics. While shape matching is a popular meshless solution, it is limited to a subset of elastic constitutive models, challenging the simulation of generic elastic constitutive models using meshless integration.
Evaluating the Impact of Green Manure Incorporation on Cotton Yield, Soil Fertility, and Net Eco-Economic Benefits
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Amyloid-β precursor protein promotes tumor growth by establishing an immune-exclusive tumor microenvironment
Abstract During initiation and progression, cancerous tissue hijacks a series of elaborate tissue homeostatic mechanisms to avoid immune surveillance, including neuro-immune interactions. Here, we show that amyloid-β precursor protein (APP) and its β-cleavage product amyloid-β1-42 (Aβ1-42), well-known in the pathogenesis of Alzheimer′s disease (AD), are expressed in multiple cancer tissues. However, the oncogenic activity of APP is due to its E1 domain, instead of Aβ1-42.
The impact of China’s diagnosis-intervention packet policy on hospit
Mingmin Zhang,1,2 Guoping Wang,1 Hairong Liu,1,2 Yufeng Wen,1,2 Lingling Chen1 1Wannan Medical College, Wuhu, People’s Republic of China; 2Anhui Key Laboratory of Philosophy and Social Sciences for Public Health Crisis Management, Wuhu, People’s Republic of China Correspondence: Mingmin Zhang, Wannan Medical College, No. 22 Wenchang West Road, Higher Education Park, Wuhu, 241002, People’s Republic of China, Email [email protected] Purpose: China’s diagnosis-intervention packet (DIP) policy, a...
High-performance On-orbit Intelligent Computing and Real-time Services for Remote Sensing Satellites Based on Space Large-scale Computing Power
Preprint Review Version 1 This version is not peer-reviewed Version 1 : Received: 22 October 2024 / Approved: 22 October 2024 / Online: 22 October 2024 (11:04:43 CEST) Wang, G.; Wan, G.; Su, Z.; Wang, Y.; Jia, Y.; Li, G.; Liang, S. High-performance On-orbit Intelligent Computing and Real-time Services for Remote Sensing Satellites Based on Space Large-scale Computing Power. Preprints 2024, 2024101714.
Effects of Fire Regime on Nitrogen Distribution in Marshlands of the Sanjiang Plain (NE China)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Frequency-Dependent Bouc-Wen Modeling of Magnetorheological Damper Using Harmonic Balance Approach
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Microwave-Solvothermal Synthesis of Mesoporous CeO2/CNCs Nanocomposite for Enhanced Room Temperature NO2 Detection
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
One-pot Preparation and the Electrochemical Properties of the composite NiCo Bimetallic Organic Framework and Carbon Quantum Dots
One-pot Preparation and the Electrochemical Properties of the composite NiCo Bimetallic Organic Framework and Carbon Quantum Dots Designing metal-organic framework (MOF) materials with high conductivity is crucial for their application in energy storage devices. In this study, a simple process, namely, one-pot hydrothermal method was used for simultaneously synthesizing the composite of carbon quantum dots (CQD) and NiCo-MOF, and the effect of various carbon sources for CQD was compared.
Natural Allelic Variations of Bch10G006400 Controlling Seed Size in Chieh-qua (Benincasa hispida Cogn. var. Chieh-qua How)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Enhanced Cotton Yield and Fiber Quality by Optimizing Irrigation Amount and Frequency in Arid Areas of Northwest China
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Cyclic Convolutional Neural Network Model Based on Artificial Intelligence
Cyclic Convolutional Neural Network Model Based on Artificial Intelligence Autores: Tianchi Ye, Guoping Wang, Changqing Cai Localización: Applied Mathematics and Nonlinear Sciences, ISSN-e 2444-8656, Vol. 8, Nº. 2, 2023, págs.
Inter-Month Nutrients Dynamic and Plant Growth in Calamagrostis angustifolia Community and Soil after Different Burning Seasons
Open AccessArticle by 1,2,3, 2,3,*, 2,3, 2,3, 2,3, 1,* and 2,3,* 1 Key Laboratory of Sustainable Forest Ecosystem Management-Ministry of Education, College of Forestry, Northeast Forestry University, Hexing Road 26, Harbin 150040, China 2 Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Shengbei Street 4888, Changchun 130102, China 3 State Key Laboratory of Black Soils Conservation and Utilization, Northeast...
The functions of triple gene block proteins and coat protein of apple stem pitting virus in viral cell‐to‐cell movement
1 INTRODUCTION To establish successful infection, plant viruses must move from the initial infected cell to adjacent cells and systemically spread in plants. Most plant RNA viruses express their movement proteins (MPs) and other cytoplasmic membrane-associated proteins and then use membrane-associated pathways and host proteins for targeting the plasmodesmata (PDs) and transporting their genomes through PDs (Deom et al., 1987; Heinlein, 2015; Roberts, 2003; Wolf et al., 1989).
BdCV1-Encoded P3 Silencing Suppressor Identification and Its Roles in Botryosphaeria dothidea, Causing Pear Ring Rot Disease
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,2, 1,2, 1,2, 1,2, 1,2 and 1,2,* 1 College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China 2 Key Laboratory of Plant Pathology of Hubei Province, Huazhong Agricultural University, Wuhan 430070, China * Author to whom correspondence should be addressed.
High-throughput generic single-entity sequencing using droplet microfluidics
Abstract Single-cell sequencing has revolutionized our understanding of cellular heterogeneity by providing a micro-level perspective over the past decades. Although heterogeneity is essential for various biological communities, the currently demonstrated platform predominantly focuses on eukaryotic cells without cell walls and their transcriptomics 1,2, leaving significant gaps in the study of omics from other single biological entities such as bacteria and viruses.
Treatments for choledocholithiasis with acute cholangitis
Back to Journals » International Journal of General Medicine » Volume 16 Original Research Gastroenterology Authors Chen L , Wu Z, Guo C, Wang G, Tu K, Jiang J Received 10 July 2023 Accepted for publication 11 October 2023 Published 16 October 2023 Volume 2023:16 Pages 4669—4680 DOI https://doi.org/10.2147/IJGM.S429781 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Scott Fraser Ling Chen,1 Zujian Wu,1 Chi Guo,1...
Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid - Nature Microbiology
Abstract Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease, and is characterized by liver inflammation and fat accumulation. Dietary interventions, such as fibre, have been shown to alleviate this metabolic disorder in mice via the gut microbiota. Here, we investigated the mechanistic role of the gut microbiota in ameliorating NASH via dietary fibre in mice.
Recent Advances in β-Glucosidase Sequence and Structure Engineering: A Brief Review
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Bei Ouyang 1,†, Guoping Wang 1,†, Nian Zhang 1, Jiali Zuo 2, Yunhong Huang 1,* and Xihua Zhao 1,* 1 College of Life Science, Jiangxi Normal University, Nanchang 330022, China 2 School of Computer and Information Engineering, Jiangxi Normal University, Nanchang 330022, China * Authors to whom correspondence should be addressed. † These authors contributed equally to this work.
Aerobic and anaerobic burning alter trace metal availability in peat soils: evidence from laboratory experiments
As global warming becomes more pronounced, climate change and human activities are leading to frequent peat fire incidents. Fire plays an important role in the environmental distribution of trace metals in peat soils. In the current study, we collected peat soils from six peatlands of the Great Khingan Mountains in Northeast China, where wildfires have often occurred in recent decades.
Genomic insights into the genetic basis of cotton breeding in China
The GWAS of the 920 MAGIC population was conducted with 2-year means from three locations and best linear unbiased prediction (BLUP) values from six environments based on 12 traits collected from three locations over 2 years. A total of 4 774 181 high-quality variants (4 391 130 SNPs + 383 051 indels) from the MAGIC population RILs were used in the mixed linear model.
Discovery of a Closterovirus Infecting Jujube Plants Grown at Aksu Area in Xinjiang of China
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Squamous Cell Papilloma of the Conjunctiva
A 74-year-old man presented to the ophthalmology department with an 8-month history of a tumor in his left eye. Examination showed a fleshy tumor with a cauliflower-like appearance involving the conjunctiva and cornea ( Fig ). An excisional biopsy was performed, and pathological analysis showed squamous cell papilloma of the conjunctiva. Histology slide showed papilloma of the conjunctiva ( Fig ).
Identification and characterization of microRNAs from in vitro-grown pear shoots infected with Apple stem grooving virus in response to high temperature using small RNA sequencing | BMC Genomics | Full Text
Juan Liu1, 2, 3, 4, XueJiao Zhang2, 5, FangPeng Zhang1, 2, 3, 4, Ni Hong1, 2, 3, 4, GuoPing Wang1, 2, 3, 4, Aiming Wang6 and LiPing Wang1, 2, 3, 4Email author Received: 3 August 2015 Accepted: 22 October 2015 Published: 16 November 2015 Abstract Background MicroRNAs (miRNAs) have functions in diverse biological processes such as growth, signal transduction, disease resistance, and stress responses in plants. Thermotherapy is an effective approach for elimination of viruses from fruit trees.
A dsRNA virus with filamentous viral particles
Nucleic acid preparations enriched in dsRNA were obtained from mycelia of C. camelliae strain LT-3-1 and analyzed by agarose gel electrophoresis. A complex pattern of eight bands was detected in LT-3-1 preparations before and after digestion with DNase I or S1 nuclease (Fig. 1a). Assuming that these bands were generated by dsRNAs, their corresponding sizes were between 2500 and 900?bp as estimated by agarose gel electrophoresis using both dsDNA and dsRNA markers (Fig. 1a).
Malignant Pleural Effusion and Ascites Induce Epithelial-Mesenchymal Transition and Cancer Stem-Like Cell Properties via VEGF/PI3K/Akt/mTOR Pathway
Author contributions: Y. Wang and T. Yin designed the research; T. Yin, G. W., S. H., G. S., C. S., Y. Z., X.W., T. Ye, L. L., D. L., F. G., P. A., X. Z., Z. M., Y. Wan. and Y. L. performed the research; Y. Wang, T. Yin, S. Y., and Y. Wei analyzed the data; T. Yin and G. W. wrote the manuscript. All authors reviewed the results and approved the final version of the manuscript. Malignant pleural effusion (PE) and ascites, common clinical manifestations in advanced cancer patients, are associated with poor prognosis.
Correction: Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products
a Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, P. R. China E-mail: muying@zju.edu.cn b Institute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, P. R. China
Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products
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