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Articles by Hang Fan
An extracellular vesicle-mediated mitochondrial transfer network critical for testosterone synthesis - Nature Cell Biology
Abstract Testosterone production by testicular Leydig cells (LCs) in male mammals is energetically demanding and prone to mitochondrial damage. Despite these challenges, LCs exhibit remarkable longevity and minimal turnover, suggesting the existence of specialized mechanisms that maintain LC mitochondrial homeostasis under such constrains. Here we identify a mitochondrial transfer network between LCs and different testicular macrophage (tMac) subpopulations.
Physically consistent global atmospheric data assimilation with machine learning in latent space
Now Berlin, Germany - January 03, 2026 Snow and black ice cover streets in Berlin’s Charlottenburg district late Friday night, January 2, 2026, extending into early Saturday, January 3, as freezing temperatures followed steady snowfall. Slippery road conditions caused vehicles to lose traction and forced drivers to slow down across major routes. Several accidents were reported, including on Berlin’s A100 city highway, where traffic was partially disrupted.
Physically consistent global atmospheric data assimilation with machine learning in latent space
Abstract Data assimilation (DA) integrates observations with model forecasts to produce optimized atmospheric states, whose physical consistency is critical for stable weather forecasting and reliable climate research. Traditional Bayesian DA methods enforce these nonlinear, flow-dependent physical constraints through empirical and tunable covariance structures, but with limited accuracy and robustness.
The Impact of two kinds of Liuzijue Qigong on Respiratory and Motor Function in Early Stroke Recovery Patients
Key Words Stroke Liuzijue Qigong Balance Functions Trunk Control Get full text access Log in, subscribe or purchase for full access. References 1. Pozuelo-Carrascosa, D.P. ∙ Carmona-Torres, J.M. ∙ Laredo-Aguilera, J.A. ... Effectiveness of respiratory muscle training for pulmonary function and walking ability in patients with stroke: a systematic review with meta-analysis International journal of environmental research and public health. 2020 Aug; 17:5356 2.
A novel latent space data assimilation framework with Autoencoder-Observation to Latent space (AE-O2L) network. Part II: observation and background assimilation with interpretability
Loading [MathJax]/extensions/MathMenu.js Jump to Content Save Email this content Share Link Copy this link, or click below to email it to a friend Email this content or copy the link directly: The link was not copied. Your current browser may not support copying via this button. Share on facebook Share on linkedin [64.137.71.25] 64.137.71.25 Sign in to annotate
Effect of Hydride Types on the Fracture Behavior of a Novel Zirconium Alloy Under Different Hydrogen-Charging Current Densities
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Because of Love, I Won't Leave: Harmonious Passion and Turnover Intention Among Primary and Secondary School Teachers
Conflicts of Interest The authors declare no conflicts of interest. References , , , , and . 2021. “The Influence of Person-Environment Fit on the Turnover Intention of Nurses in Jordan: The Moderating Effect of Psychological Empowerment.” Nursing Research and Practice 2021: 6688603. https://doi.org/10.1155/2021/6688603. , , , and . 1986. “Dynamics of Childhood and Adolescent Personality Traits and Adolescent Drug Use.” Developmental Psychology 22, no. 3: 403–414.
Multimodal MRI Deep Learning for Predicting Central Lymph Node Metastasis in Papillary Thyroid Cancer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Tailoring Na+ Diffusion Kinetics and Structural Stability of P2‐Layered Material by W‐Lattice Doping†
Supporting Information Filename Description cjoc202400861-sup-0001-supinfo.pdfPDF document, 1 MB Appendix S1: Supporting Information References 1 ; ; ; ; ; ; ; ; ; ; ; Phase Engineering of Ni-Mn Binary Layered Oxide Cathodes for Sodium-Ion Batteries. J. Energy Chem. 2024, 91, 501–511. 2 ; ; ; ; ; ; ; ; ; ; ; Precise Regulation of Particle Orientation for Ni-Rich Cathodes with Ultra-Long Cycle Life. Nano Energy 2024, 129, 110008.
Sequencing and Analysis of Wolbachia Strains from A and B Supergroups Detected in Sylvatic Mosquitoes from Brazil
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Digital technology‐based business model design and innovation to address grand challenges: A process model
Corresponding Author Wei Zhang Department of Innovation, Entrepreneurship and Strategy, School of Economics and Management, Tsinghua University, Beijing, P. R. China Correspondence Wei Zhang, Department of Innovation, Entrepreneurship and Strategy, School of Economics and Management, Tsinghua University, Beijing 100084, P. R. China. Email: zhangw3@sem.tsinghua.edu.cn Search for more papers by this author
Research on Three-Dimensional Cloud Structure Retrieval and Fusion Technology for the MODIS Instrument
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Research on MODIS Satellite Three-Dimensional Cloud Structure Retrieval and Fusion Technology
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 21 March 2024 / Approved: 21 March 2024 / Online: 21 March 2024 (15:18:40 CET) Qin, Y.; Liu, Y.; Wang, F.; Fan, H.; Zhou, Y.; Duan, J. Research on MODIS Satellite Three-Dimensional Cloud Structure Retrieval and Fusion Technology. Preprints 2024, 2024031321. https://doi.org/10.20944/preprints202403.1321.v1 Qin, Y.; Liu, Y.; Wang, F.; Fan, H.; Zhou, Y.; Duan, J.
A Two-Step Model-Based Reconstruction and Imaging Method for Baseline-Free Lamb Wave Inspection
Open AccessArticle by Hang Fan 1, Fei Gao 2,3,4,*, Wenhao Li 3 and Kun Zhang 1 1 Science and Technology on Reactor System Design Technology Laboratory, Nuclear Power Institute of China, Chengdu 610213, China 2 School of Reliability and Systems Engineering, Beihang University, Xueyuan Road No. 37, Haidian District, Beijing 100191, China 3 Advanced Manufacturing Center, Ningbo Institute of Technology, Beihang University, Ningbo 315100, China 4 Key Lab of Modern Optical Technologies of Jiangsu...
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
Modeling SARS-CoV-2 in mice Among the research tools necessary to develop medical interventions to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, high on the list are informative animal models with which to study viral pathogenesis. Gu et al. developed a mouse model in which a SARS-CoV-2 strain was infectious and could cause an inflammatory response and moderate pneumonia.
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
Modeling SARS-CoV-2 in mice Among the research tools necessary to develop medical interventions to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, high on the list are informative animal models with which to study viral pathogenesis. Gu et al. developed a mouse model in which a SARS-CoV-2 strain was infectious and could cause an inflammatory response and moderate pneumonia.
A Thermostable mRNA Vaccine against COVID-19
Highlights • Development of LNP-encapsulated mRNA vaccine (ARCoV) targeting the RBD of SARS-CoV-2 • ARCoV induces neutralizing antibodies and T cell immunity in mice and NHPs • ARCoV vaccination confers full protection against SARS-CoV-2 challenge in mice • ARCoV is a thermostable vaccine candidate for phase I studies Summary There is an urgent need for vaccines against coronavirus disease 2019 (COVID-19) because of the ongoing SARS-CoV-2 pandemic.
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
By Hongjing Gu, Qi Chen, Guan Yang, Lei He, Hang Fan, Yong-Qiang Deng, Yanxiao Wang, Yue Teng, Zhongpeng Zhao, Yujun Cui, Yuchang Li, Xiao-Feng Li, Jiangfan Li, Na-Na Zhang, Xiaolan Yang, Shaolong Chen, Yan Guo, Guangyu Zhao, Xiliang Wang, De-Yan Luo, Hui Wang, Xiao Yang, Yan Li, Gencheng Han, Yuxian He, Xiaojun Zhou, Shusheng Geng, Xiaoli Sheng, Shibo Jiang, Shihui Sun, Cheng-Feng Qin, Yusen Zhou Published Online30 Jul 2020 DOI: 10.1126/science.abc4730
Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy
New Results Hongjing Gu, Qi Chen, Guan Yang, Lei He, Hang Fan, Yong-Qiang Deng, Yanxiao Wang, Yue Teng, Zhongpeng Zhao, Yujun Cui, Yuchang Li, Xiao-Feng Li, Jiangfan Li, Nana Zhang, Xiaolan Yang, Shaolong Chen, Guangyu Zhao, Xiliang Wang, Deyan Luo, Hui Wang, View ORCID ProfileXiao Yang, Yan Li, Gencheng Han, Yuxian He, Xiaojun Zhou, Shusheng Geng, Xiaoli Sheng, Shibo Jiang, Shihui Sun, Cheng-Feng Qin, Yusen Zhou doi: https://doi.org/10.1101/2020.05.02.073411 Abstract Coronavirus disease 2019...
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