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Articles by Lu Yan
Stomatin organizes laterally segregated membrane microdomains to modulate transmembrane transport and signal transduction
Abstract Stomatin is a member of the SPFH (Stomatin, Prohibitin, Flotillin, and HflK/C) protein family, and has been proposed to scaffold functional membrane microdomains (FMMs) on the plasma membrane. Functionally, stomatin has been reported to associate with diverse partner proteins and is implicated in various cellular processes. However, the mechanisms by which it organizes FMMs and exerts its regulatory roles remain unclear.
Icariin prevents acute high-altitude pulmonary edema in rats by alleviating oxidative stress and modulating cuproptosis-related proteins
Abstract This study aimed to evaluate the therapeutic efficacy and underlying mechanisms of ICA in AHAPE. Rats were exposed to a hypobaric hypoxic chamber simulating an altitude of 6000 m (ascent rate: 10 m/s, pressure: 47.3 kPa, O2 concentration: 9.9%) for 3 days to induce AHAPE. To prevent AHAPE, rats were pretreated with ICA (30, 60, or 120 mg/kg/day) or acetazolamide (100 mg/kg/day) for 7 consecutive days before exposure.
Weathering Summer
A traffic police officer carries a child across a waterlogged street during heavy rain in Duyun, Guizhou Province, on May 19 (XINHUA) In summer 2026, much of the northern hemisphere is sweltering under record-breaking heatwaves. From Europe to Asia, thermometers sometimes exceeded 40 degrees Celsius, straining power grids, endangering vulnerable populations, and exposing the limits of urban infrastructure designed for a cooler past.
Furnace, Factory, Future-- ChinAfrica
Visitors learn about the HyperEngine produced by Chinese tech giant Xiaomi at the company’s automobile factory in Beijing on 16 June 2025 (XINHUA) Inside the workshop, giant robotic arms swing back and forth, the 9,100-tonne casting press rumbles like thunder and automated trolleys weave through the aisles. This is not the film set of a sci-fi blockbuster; it’s a typical weekend scene at a car factory of Chinese tech giant Xiaomi in Beijing.
Exercise intensity modulates interorgan communication and is associated with cardiometabolic health outcomes in humans
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ArticleOnline now102988Open access Affiliations & Notes 1Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, 10065, United States of America 2Institute for Health and Sport, Victoria University, Melbourne, VIC, Australia 3Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland 4Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, United States of America 5Weill Cornell Medical...
By Luke Olsen, Javier Botella, Douglas Barrows, Ethan Romero, Mutsumi Katayama, Ece Kilic, Christopher Peralta, Nadège Zanou, Henry Sanford, Laurie Ann Farrell, Christopher L. Axelrod, Kaja Plucinska, Jeanne M. Walker, Lu Yan, Katie Fredrickson, Olivier Pourquie, Jeremy Robbins, Ekaterina V. Vinogradova, Henrik Molina, Nicolas Place, John Kirwan Verified, Juleen R. Zierath, Anna Krook, Robert Gerszten, David Bishop, Paul Cohen, Kaitlyn Baird
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Cell Reports Medicine
Verified
Torsins organize CLCC1 assembly to safeguard ER bilayer and lipid homeostasis
Keywords lipid metabolism ER membrane homeostasis AAA+ ATPase torsins Get full text access Log in, subscribe or purchase for full access. References 1. Mathiowetz, A.J. ∙ Olzmann, J.A. Lipid droplets and cellular lipid flux Nat. Cell Biol. 2024; 26:331-345 2. Feingold, K.R. Lipid and Lipoprotein Metabolism Endocrinol. Metab. Clin. N. Am. 2022; 51:437-458 3. Roth, G.A. ∙ Abate, D. ∙ Abate, K.H. ...
Efficacy and Safety of 12-Week Coblopasvir/Sofosbuvir Regimen for Hepatitis C in Northwest China: A Multi-Center Prospective Study
DAAs direct-acting antiviral agents EOT end of treatment GLE/PIB glecaprevir/pibrentasvir GT genotype HCC hepatocellular carcinoma HCV Hepatitis C virus HIV human immunodeficiency virus NRDL national reimbursement drug list PWID people who inject drugs SOF/VEL sofosbuvir/velpatasvir SVR12 sustained virologic response 12 week TE transient elastography VR virological respense WHO World Health Organization 1 Background Hepatitis C virus (HCV) infection continues to be a major global health...
The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum
ArticleVolume 86, Issue 7p1362-1376.e5 Affiliations & Notes 1State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China 2Peking-Tsinghua Joint Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China 3State Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China 4National Biomedical Imaging Center,...
Study on key strata and surface deformation prediction for overburden separation grouting mining in adjacent panel based on foundation beam theory
Abstract With the intensive exploitation of coal resources, the phenomenon of surface deformation becomes more prominent. This issue has directly threatened the safety of surface building structures and the regional ecological balance. Based on the elastic foundation beam theory, we investigated the deformation characteristics of key strata under overburden separation grouting in adjacent panel mining and predicted surface deformation.
A Comprehensive Analysis of Type I Interferon Risk Gene Signatures in Systemic Lupus Erythematosus
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the of this article. Supporting Information Filename Description exd70211-sup-0001-FigureS1-S16.docxWord 2007 document , 1.9 MB Figure S1: MR analysis of causal effect of HERC5 on SLE. Forest plot: Reflection of effect sizes for individual SNPs (black markers) and overall estimates (red markers) using IVW and MR Egger methods.
WTAP Interferes With Ferroptosis by Regulating the m6A Modification of SF3B1 to Mediate the Malignant Progression of Endometrial Cancer
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The analyzed data sets generated during the present study are available from the corresponding author on reasonable request. References 1, , , et al., “Endometrial Cancer,” Nature Reviews Disease Primers 7, no. 1 (2021): 88. 2, , and , “Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment,” Journal of Clinical Oncology 34, no. 35 (2016): 4225–4230.
Interface Chemical Welding by Nanoparticles Endow Ceramic Aerogels with Broad‐Temperature Microwave Absorption and Thermal Insulation
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm73184-sup-0001-SuppMat.docx12.1 MB Supporting Information References 1, , , , , , , , , , , , , , , , , Nano-Micro Lett. 2025, 17, 164. 2, , , , , , , , , , , Matter 2025, 102367, https://doi.org/10.1016/j.matt.2025.102367.
Grass Carp Catalase Inhibits Interferon Regulatory Factor‐7 to Promote Grass Carp Reovirus Replication
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description jfd70076-sup-0001-supinfo.docxWord 2007 document , 16.8 MB Data S1: Supporting Information. References , , , and . 2014. “Effect of Bovine Adenovirus 3 on Mitochondria.” Veterinary Research 45, no. 1: 45. https://doi.org/10.1186/1297-9716-45-45. , , , and . 2021. “Mitochondria as a Cellular Hub in Infection and Inflammation.” International Journal of Molecular Sciences 22, no. 21: 11338.
Unlocking Opportunities-- ChinAfrica
Primary school students in Atushi (Artux), Kizilsu Kirgiz Autonomous Prefecture, pose for photographs after a gong and drum performance on 12 September (XINHUA) A quiet revolution is underway in the vast cotton fields of Bortala Mongolian Autonomous Prefecture in north Xinjiang where harvesting machines, guided by digital sensors, operate with minimal human intervention.
A Dynamic Installation of Interference Bushing Method Based on Electromagnetic Driving to Enhance the Joining Quality of CFRP Structures
Conflicts of Interest The authors declare no conflicts of interest. References 1, , , et al., “CFRP Drilling Under Throttle and Evaporative Cryogenic Cooling and Micro-Lubrication,” Composite Structures 267 (2021): 113916, https://doi.org/10.1016/j.compstruct.2021.113916. 2, , , et al., “Recent Advances of Interphases in Carbon Fiber-Reinforced Polymer Composites: A Review,” Composites Part B: Engineering 233 (2022): 109639, https://doi.org/10.1016/j.compositesb.2022.109639.
Worldwide Research Trends on the Immunotherapy-Based Treatment of Ovarian Cancers: A Bibliometric and Visual Analysis
Abstract Purpose Immunotherapy-based treatment has shown significant clinical potential in various cancers. This study provides a comprehensive bibliometric analysis of the immunotherapy landscape in ovarian cancer over the last decade, identifying leading trends, influential contributors, and key areas of development. Methods A systematic literature search was conducted in the Web of Science Core Collection for publications on immunotherapy drugs used in ovarian cancer between 2014 and 2024.
Shaping the Future-- ChinAfrica
A drone sows drought-tolerant, water-efficient rice in Anqing, Anhui Province, on 6 June (VCG) In July 1956, the First Automobile Works in Changchun, Jilin Province - part of the country’s traditional northeastern industrial base - produced the first car made in the People’s Republic of China (PRC). This achievement was a glimpse into the 156 key projects outlined in the country’s First Five-Year Plan (FYP) (1953-1957).
Magnetic stimulation delivered through an aligned nanofibrous scaffold composed of magnetic graphene hybrids promotes optic nerve regeneration
Keywords optic nerve magnetic stimulation coaxially nanofibers magnetic graphene hybrids poly(lactic-co-glycolic) acid (PLGA) aligned nanofibrous scaffold vision function retina ganglion cells (RGC) Introduction The optic nerve, which originates from the central nervous system (CNS), transmits visual information from the eye to the brain. It is primarily composed of axons from retinal ganglion cells (RGCs).
Summary of Best Evidence for Psychosocial Interventions in Adults With
Introduction Alcohol Use Disorder (AUD) is defined as a problematic pattern of alcohol use leading to clinically significant impairment or distress.1 It is the most common of all substance use disorders worldwide, with a prevalence ranging from 4% to 11%.2,3 The prevalence rates in Liaoning Province, Tianjin Municipality, and Ningxia Hui Autonomous Region of China were 4.2%, 8.5%, and 7.5%, respectively, with most cases occurring among adults.4–6 AUD not only severely impacts individuals’...
Comparison of Two Types of Silicone Hydrogel Bandage Contact Lenses Used as Bandage Contact Lenses After Transepithelial Photorefractive Keratectomy - Randomized, Double-Blind, Contralateral Eye Study
You are already at the latest version Purpose: To compare the clinical outcomes of Lotrafilcon A and Balafilcon A silicone hydrogel contact lenses used as therapeutic bandage contact lenses (BCL) following transepithelial photorefractive keratectomy (TPRK).
A Symphony of Voices-- ChinAfrica
NPC deputies attend the opening meeting of the third session of the 14th NPC in Beijing on 5 March (XINHUA) The Two Sessions - the annual gathering of China’s top legislature, the National People’s Congress (NPC) and the top political advisory body, the National Committee of the Chinese People’s Political Consultative Conference (Two Sessions) - are not just pivotal events in the country’s political calendar. They resonate deeply with ordinary citizens, influencing daily life across the nation.
Unveiling the ESIPT Luminescence Mechanism of 4′-N,N-Diethylamino-3-Hydroxyflavone in Ionic Liquid: A Computational Study
Article Menu /ajax/scifeed/subscribe Altmetric announcement Help format_quote Cite Need Help? Find support for a specific problem in the support section of our website. Please let us know what you think of our products and services. Visit our dedicated information section to learn more about MDPI.
Worldwide research trends on the immunotherapy-based treatment of ovar
Back to Journals » Journal of Multidisciplinary Healthcare » Volume 18 Authors Yan L, Liu Y, Zhang Z, Du F Received 4 March 2025 Accepted for publication 13 July 2025 Published 25 July 2025 Volume 2025:18 Pages 4197—4217 DOI https://doi.org/10.2147/JMDH.S526280 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Pavani Rangachari Lu Yan, Yibin Liu, Zhiqiang Zhang, Feida Du Department of Gynecology, Second Hospital of...
化肥减量配施生物有机肥对水稻产量、土壤结构和土壤固碳增汇能力的影响
In order to explore the effects of nitrogen reduction combined with application of bio-organic fertilizer on rice yield，soil structure and soil carbon sequestration capacity，four treatments were set up，including no nitrogen fertilizer(CK)，conventional fertilizer(T1)，10% nitrogen reduction combined with application of bio-organic fertilizer(T2) and 20% nitrogen reduction combined with application of bio-organic fertilizer(T3).The results showed that，compared with T1 treatment，nitrogen...
China's ethnic cultures shine at national games By Lu Yan
A Flying Dragon Sword performance by the Guizhou Province team during the 12th National Traditional Games of Ethnic Minorities in Sanya, Hainan Province, on November 23 (XINHUA) Zhu Mengdan, a 15-year-old from the Li ethnic group, grew up climbing betel nut trees and coconut palms. However, she had never imagined that the games she played with her friends would one day evolve into an official event at a national sporting competition.
Fighting climate change requires a shared long-term vision and concerted actions
Support Village Voice News With a Donation of Your Choice. In November, Wang Yafei, a resident of Handan in Hebei Province, purchased three new household appliances: a French door refrigerator, a 75-inch television and a washer-dryer combo. Thanks to a government-backed trade-in program for consumer goods, he received a substantial discount when exchanging his old appliances, which he had used for about a decade, for the latest, most energy-efficient models.
Why Do People Gather? A Study on Factors Affecting Emotion and Participation in Group Chats
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Optimization of Operation Strategy of Multi-Islanding Microgrid Based on Double-Layer Objective
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Horticulturae | Free Full-Text | Genome-Wide Identification of Nucleotide-Binding Site-Leucine-Rich Repeat Gene Family in Cymbidium ensifolium and Expression Profiles in Response to Fusarium Wilt Infection
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Low-Sidelobe Imaging Method Utilizing Improved Spatially Variant Apodization for Forward-Looking Sonar
1. Introduction Imaging sonars can directly present underwater scene information, providing strong support for underwater target detection and recognition [1,2,3]. Imaging sonars can be divided by their detection coverage and system construction type into: forward-looking [4], side-looking [5] and down-looking solutions [6].
Yolk-Shell type Carbon-Silica Nanoarchitecture Dispersed and Stabilized Ru Nanoparticles for Enhanced Hydrogenation of Aromatic Compounds
Yolk-Shell type Carbon-Silica Nanoarchitecture Dispersed and Stabilized Ru Nanoparticles for Enhanced Hydrogenation of Aromatic Compounds Hydrogenation of aromatic rings can be used not only for synthesis fine chemicals, but also for hydrogen storage and transportation using organic hydride.
Heteroaryl 2‐Sulfonamide Synthesis by SN2 Reaction-Oxidation Cascade
Conflict of interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Pairing-Free Certificate-Based Proxy Re-Encryption Plus Scheme for Secure Cloud Data Sharing
1. Introduction 1.1. Background With the rapid advancement and convergence of cloud computing, big data, and related technologies, public cloud storage has become immensely popular. Users increasingly depend on cloud storage solutions for online data storage and sharing. However, this convenience comes with security concerns. When users store their data in the cloud, they lose direct control, leading to potential issues such as privacy breaches and compromised data confidentiality.
Media abnormal tone and cross section of stock returns: Evidence from China
REFERENCES (2002) Illiquidity and stock returns: cross-section and time-series effects. Journal of Financial Markets, 5(1), 31–56. & (2004) Is all that talk just noise? The information content of internet stock message boards. The Journal of Finance, 59(3), 1259–1294. , & (2022) Media abnormal tone, earnings announcements, and the stock market. Journal of Financial Markets, 61, 100683. & (2006) Investor sentiment and the cross-section of stock returns. The Journal of Finance, 61(4), 1645–1680.
Genome-Wide Identification of bZIP Transcription Factors in Cymbidium ensifolium and Analysis of Their Expression under Low-Temperature Stress
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
President of the Jinan Taiwan Association: The exchange of youth on both sides of the Taiwan Strait in Hebei Province "one tea and a thousand flavors" has touched the hearts of the people on both sides of the strait
Jinan, December 12 (ZXS) -- President of the Jinan Taiwan Association: Youth exchanges between the two sides of the Taiwan Strait in Hebei Province "one tea and a thousand flavors" have touched the hearts of the people on both sides of the strait Written by Lu Yan Cloth, tea appreciation, warm cup, tea, warm brewing, brewing......
Cheng Xiulan, president of the Jining Taiwanese Friendship Association: Let Taiwan compatriots pursue their dreams in the mainland with peace of mind
Jining, December 12 (CNN) -- Cheng Xiulan, president of the Jining Taiwanese Friendship Association: Let Taiwan compatriots pursue their dreams in the mainland with peace of mind Written by Lu Yan "The two old people are like my relatives and an indispensable responsibility in my life.
"Alishan girl" Shen Yuying has "landed" for 40 years: she has no regrets in choosing the mainland in this life
Binzhou, Shandong, December 12 (CNN) -- Shen Yuying, the "Alishan girl" has "landed" for 12 years: she has no regrets in choosing the mainland in this life Written by Lu Yan "At that time, it was not as easy to come to the mainland as it is now, and in 1982, my husband and I came to the mainland under the pretext of visiting relatives in Japan." Today, 78-year-old "Alishan girl" Shen Yuying has settled in Huimin County, Binzhou City, Shandong Province for 40 years, and she still remembers the...
East-West Q丨Ma Xin: What are the genetic differences between the different civilizations of the East and the West?
China News Service Jinan, December 12 (Xinhua) -- What are the genetic differences between the different civilizations of the East and the West?
Two generations of Taiwan businessmen "relayed": "green water and green mountains" and "dream-building" rural reservoir areas
Weifang, 10 Oct (Zhongxin Net) -- Two generations of Taiwan businessmen "relayed": "green water and green mountains" and "dream-building" rural reservoir areas Written by Lu Yan On October 10, walking into the west bank of Xiashan Reservoir located in Xiashan Ecological Economic Development Zone, Weifang City, Shandong Province, the 21-kilometer-long willow embankment around the lake was like a stretched arm, embracing the green water and green mountains in his arms.
Bimetallic metal-organic framework with high enzyme-mimicking activity for an integrated electrochemical immunoassay of carcinoembryonic antigen
Bimetallic metal-organic framework with high enzyme-mimicking activity for an integrated electrochemical immunoassay of carcinoembryonic antigen Metal-organic framework (MOF) shows excellent catalytic activity and have been widely applied in diseases and tumors diagnosis analysis. However, current assay methods usually involve cumbersome configuration and complicated procedures, which inhibited their practical applications.
Data packet loss rate
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Weidong Cui's research works
What is this page? This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile. It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible.
Meta-analysis of influencing factors of incontinence dermatitis in ICU based on intelligent medical systems
In recent years, the number of patients with incontinence dermatitis in the ICU has gradually increased, and this condition can cause great harm to patients. Therefore, prevention and treatment of incontinence dermatitis is currently a hot research topic.
JNU launches 70th anniversary of College of Chinese Language and Culture
Date: April 19, 2023 Author:LU Yufei, LU Yan, HUANG Dandan Translator: YIN Wenqian, YANG Jie Jinan University held the launch ceremony of the 70th anniversary of the College of Chinese Language and Culture (CCLC), also known as the Guangzhou Overseas Chinese School, and the appointment ceremony of the president of its Alumni Association on April 15.
Towards a “Positive Landscape”: An Integrated Theoretical Model of Landscape Preference Based on Cognitive Neuroscience
1. Introduction As presented in the European Landscape Convention (ELC), a landscape is “an area, as perceived by people, whose character is the result of the action and interaction of natural and/or human factors” []. The concept of landscape preference (LP) was first put forward by scholars in the late 1960s, and focuses on human perceptions, attitudes, and preferences regarding the landscape, as well as reasons why some landscapes are more favored than others [,,].
CrossFix: Resolution of GitHub issues via similar bugs recommendation
REFERENCES 1, , . An exploratory study of the pull-based software development model. In: Proceedings of the 36th international conference on software engineering ACM; 2014: 345-355. 2, , . Work practices and challenges in pull-based development: the contributor's perspective. In: 2016 IEEE/ACM 38th international conference on software engineering (ICSE) IEEE; 2016: 285-296. 3, , . Towards prioritizing Github issues.
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