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Articles by Min Wei
RNF130 ameliorates renal injury and inflammation by inhibiting macrophage pyroptosis through ubiquitination degradation of PDCD4 in male mice
Abstract Macrophage pyroptosis has been identified as a contributor to acute kidney injury (AKI), but the underlying mechanisms involved remain unclear. Herein, we identify that ring finger protein 130 (RNF130) RNF130 is significantly downregulated in both mice and patients with AKI. Myeloid cell-specific loss of RNF130 aggravates renal pathological damage and facilitates macrophage pyroptosis in AKI mouse models.
Reoviridae -derived short trimerization domain for stabilizing homo-trimerization of vaccine immunogens and therapeutic proteins
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Abstract Trimerization motifs play pivotal roles in structural biology and therapeutic protein engineering. Here, we describe a short trimerization motif (rFd1303) derived from the Reoviridae family reovirus σ1 protein. Compared with the widely used T4-Foldon, the rFd1303 increased recombinant protein yields. The rFd1303-fused immunogens of SARS-CoV-2 spike and influenza hemagglutinin elicited antibody responses comparable to T4-Foldon-fused controls in mice.
By Min Wei, Qingfang Bu, Jin Xiao, Lunzhi Yuan, Huilin Guo, Yang Huang, Hui Sun, Kai Wang, Zonglin Li, Min Lin, Zhaoming Lu, Chen Zheng, Jijing Chen, Jiahua Gao, Zikang Wang, Zehong Huang, Ruojing Bai, Ying Liu, Jian Ma, Yunda Hong, Youfeng Wang, Jiayi Wu, Yifan Yin, Shengxiang Ge, Zizheng Zheng, Yixin Chen, Yi Guan, Hai Yu, Tianying Zhang, Jun Zhang, Shaojuan Wang, Qingbing Zheng, Yangtao Wu, Ningshao Xia, Yali V. Zhang, Quan Yuan, Jinmiao Shi
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Nature
Verified
Ascending for vitality: how older visitors experience wellness on Mount Tai, China
ABSTRACT Heritage mountains provide a distinctive tourism setting in which natural scenery, bodily movement, cultural meaning, ritual practice, and spatial support are experienced within the same visit. This study examines short-term perceived wellness among older visitors in such a mountain heritage setting, focusing on vitality, psychological restoration, and social interaction.
Leveraging large language models to generate multiple-choice questions for epilepsy education
Abstract Background: Large language models (LLMs) are increasingly used to generate medical assessment items, but their reliability for disease-specific question writing remains uncertain. We benchmarked seven LLMs for epilepsy single-best-answer multiple-choice question generation under a standardized blueprint, focusing on structural compliance, clinical accuracy, expert-rated quality and educational usability.
Obinutuzumab β for aquaporin-4-positive neuromyelitis optica spectrum disorder: a phase 3 randomized controlled trial
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Abstract Although CD20-directed B cell depletion has long been used in neuromyelitis optica spectrum disorder (NMOSD), high-quality, large-scale, randomized controlled trials remain limited. In this multicenter, randomized, double-blind phase 3 trial, we evaluated obinutuzumab β (MIL62), a novel glycoengineered type II anti-CD20 monoclonal antibody, in patients with NMOSD.
By Lei Wu, Liangliang Gu, Weihao Fan, Min Wei, Tingjun Dai, Xiaoling Li, Lianchen Xiao, Dai-Shi Tian, Ruisheng Duan, Xiaofeng Li, Yuming Xu, Huaxing Meng, Ting Chen, Feng Gao, Juan Feng, Huan Yang, Cun-Jin Zhang, Qiang Meng, Zhaoyou Meng, Feng Qiu, Hongyu Zhou, Wei Qiu, Qing Zhang, Hong liu, Zhe Wu, Zhe Wang, Weizhou Zang, Feng Xiang, Jinjin Liang, Sijun Liu, Xifang Liu, Junbin Chen, Feng LI, Dehui Huang, Feipeng Zhai, Runxiu Zhu, Bingmei Deng, Zunbo Li
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Nature
Verified
Excitatory paraventricular thalamus–posterior insular cortex circuit mediates pain–anxiety comorbidity in diabetic neuropathy
Abstract Painful diabetic neuropathy (PDN) is frequently accompanied by anxiety, yet the neural circuit mechanisms associated with nociceptive hypersensitivity to affective dysfunction remain unclear. Here we combined brain-wide c-Fos mapping, viral tracing, in vivo fiber photometry, whole-cell recordings, and projection-specific opto/chemogenetics in a mouse model of streptozotocin-induced PDN to define a thalamo–cortex circuit for pain–anxiety comorbidity.
Admission complete blood count-derived inflammatory indices for risk stratification in hemorrhagic fever with renal syndrome: comparative performance of NLR, PLR, SII, LMR, and the neutrophil-to-red blood cell ratio
Abstract Background: Hemorrhagic fever with renal syndrome (HFRS) requires early risk stratification, yet the comparative value and reproducibility of complete blood count (CBC)-derived inflammatory indices remain unclear. We compared admission neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), lymphocyte-to-monocyte ratio (LMR), and neutrophil-to-red blood cell ratio (NRR) for identifying severe disease and 28-day mortality.
A Risk Prediction Model for Progression-Free Survival in Endometrial Cancer Integrating Clinicopathological Variables and Routine Laboratory Indicators
Back to Journals » International Journal of Women's Health » Volume 18 Authors Liang S, Lu X, Du W, Wei M, Sun J, Jing L Received 15 April 2026 Accepted for publication 7 July 2026 Published 17 July 2026 Volume 2026:18 617159 DOI https://doi.org/10.2147/IJWH.S617159 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Matteo Frigerio Sheng Liang, Xiaoyuan Lu, Wensheng Du, Min Wei, Jieyun Sun, Li Jing Department of...
Moldogenicity of dominant culturable molds in cigar tobacco leaves and GC-IMS–based analysis of volatile organic compounds
Abstract Introduction: Cigar tobacco leaves (CTLs) are nutrient-rich and susceptible to mold contamination during fermentation and storage. This study aims to investigate the specific volatile profiles of dominant culturable molds recovered under the applied isolation conditions in CTLs and to establish a robust volatile organic compounds (VOCs)-based targeted monitoring strategy for preventing early-stage mold outbreaks.
18F-FDG-PET/CT-negative gastric cancer employs glutamine-based gluconeogenesis and fatty acid oxidation to support tumor growth
Abstract Most tumors exhibit increased glucose uptake and reprogram metabolism to aerobic glycolysis to meet their demands for macromolecule biosynthesis and energy production. Consequently, PET/CT using 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG-PET/CT) has been developed and is clinically utilized in cancer imaging diagnostics. However, numerous cancers demonstrate negative imaging during 18F-FDG-PET/CT detection, suggesting these cancers employ alternative metabolic rewiring.
PLOS Neglected Tropical Diseases
Loading metrics Open Access Peer-reviewed Research Article Citation: Wei M, Xiao Z, Cao J, Du X, Li M, Zhang R, et al. (2026) The role of soluble thrombomodulin (sTM) in risk stratification of hemorrhagic fever with renal syndrome and prognostic assessment. PLoS Negl Trop Dis 20(3): e0014132. https://doi.org/10.1371/journal.pntd.0014132 Editor: Stephanie N.
Stability in the dilute limit - Nature Materials
Highly dilute metal dopants arrest nanoparticle sintering by electronically stabilizing a few critical surface atoms, redefining how catalyst stability can be engineered at the atomic scale.
Sorting nexin 10 knockdown: new strategies for alleviating sepsis-associated acute lung injury
Braz. J. Med. Biol. Res.2026;59:e15117. Open Access Peer-Reviewed Research Articles DOI: 10.1590/1414-431X2025e15117 Acute lung injury (ALI) is a common complication of sepsis in connection with excessive inflammation and accumulation of oxidative stress. Sorting nexin 10 (SNX10) is a sorting nexin family member involved in inflammatory processes. This study aimed to explore the function of SNX10 in ALI. The cecal ligation and puncture (CLP) model was established to induce ALI in C57BL/6J mice.
Conformationally Constrained Bidentate Ligands Drive Record-High NIR Quantum Yield in Cu Nanoclusters
Abstract Click to copy section linkSection link copied! Atom-precise copper nanoclusters (Cu NCs) with near-infrared (NIR) luminescence show promise in biomedical and optoelectronic applications, due to their cost-effectiveness, low toxicity, and tunable photophysics. However, their practical application is limited by extremely low NIR photoluminescence quantum yields (PLQYs) (<1%) at room-temperature (RT) in solution, as well as their pronounced sensitivity to oxidation.
Conformationally Constrained Bidentate Ligands Drive Record-High NIR Quantum Yield in Cu Nanoclusters
Journal of the American Chemical Society Cite this: J. Am. Chem. Soc. 2026, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
CKAP2L promotes endometrial cancer progression by suppressing AKT ubiquitination and activating the PI3K/AKT signaling pathway
Abstract Objective: Cytoskeleton-associated protein 2-like (CKAP2L), a microtubule-associated protein that serves as a structural component of the spindle pole and a cell cycle-related protein, acts as an oncogene in several cancers. This study seeks to elucidate the role of CKAP2L in endometrial cancer (EC) and to investigate its underlying mechanisms. Methods: The correlation between CKAP2L and clinical features was analyzed utilizing bioinformatics approaches.
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation - Communications Biology
Abstract The mRNAs of inflammatory factors often contain unstable AU-rich elements (AREs) within their 3’ untranslated regions (3’UTRs), and HuR is a key ARE-binding protein to recognize such elements. However, the roles of other Hu family member (s) remain unclear. In this study, we show an inflammatory stimulation-induced short-form and cytoplasm-localized HuB (Hel-N2).
Concurrent intracranial hemorrhage and spontaneous tumor Lysis syndrome as the initial presentation of KMT2A::AFF1-rearranged adult ALL: a case report
Abstract Background: KMT2A::AFF1-rearranged ALL is a high-risk subtype with an aggressive course. However, the simultaneous occurrence of catastrophic intracranial hemorrhage (ICH) and spontaneous tumor lysis syndrome (TLS) as the initial presentation is rare in adult patients and remains poorly characterized in the literature. Case Presentation: A previously healthy 19-year-old Chinese male was admitted with sudden-onset drowsiness and impaired consciousness.
Rui Zhang - OCT News
July 13, 2025 | Cardiology | Peking Union Medical College Background:Given the challenges faced during percutaneous coronary intervention (PCI) for heavily calcified lesions, accurately predicting PCI success is crucial for enhancing patient outcomes and optimizing procedural strategies.
Embedded‐type Cu Nanoparticle with Largely Enhanced Catalytic Activity and Stability Towards Methanol Steam Reforming
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Optimization design and performance analysis of a rotary vane magnetorheological damper for vehicle suspension based on NSGA-II
Ayuda Buscar en la ayuda Buscar en la ayuda Optimization design and performance analysis of a rotary vane magnetorheological damper for vehicle suspension based on NSGA-II Jiaqi Wang [1] ; Guoping Wang [1] ; Min Wei [1] ; Rilang Jiang [2] ; Zhuang Jin [1] ; Lingyun Wang [1] [1] National Key Laboratory of Complex Multibody System Dynamics, Nanjing University of Science and Technology, Nanjing, China [2] School of Mechanical Engineering, Zhejiang Sci-Tech University, Hangzhou, China...
Differences in Glucose Metabolism Between Single Memory Domain and Multidomain Subjective Cognitive Decline: A Longitudinal Study From SILCODE
1 Introduction Alzheimer's disease (AD) is a neurological disease which has a high disease burden and an extremely increasing prevalence [1-4]. Due to the lack of clinical treatments for AD, early detection of AD is particularly important [5]. Subjective cognitive decline (SCD) is marked by persistent self-perceived decline in cognitive functioning, but objective cognitive assessment is not impaired [6].
Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses
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Keywords near-infrared light color vision upconversion nanoparticle nanocomposites contact lenses spectrum visual behavior Introduction Light plays a particularly essential role in conveying a significant amount of external information for living organisms to comprehend the world.1,2 However, mammals can only perceive a small fraction of the electromagnetic spectrum as visible light, typically in the 400–700 nm range.3,4 This means that over half of the solar radiation energy, existing as...
By Yuqian Ma, Yunuo Chen, Sheng Wang, Zi-Han Chen, Yuanwei Zhang, Ling Huang, Xinxin Zhang, Fei Yin, Yunxuan Wang, Mingzhu Yang, Zhanjun Li, Kai Huang, Xin Fang, Zishuo Li, Minghong Wang, Wenhui Liu, Jia-Nan Li, Longfei Li, Hang Zhao, Min Wei, Yiming Shi, Rong Liu, Mei Zhang, Jutao Chen, Jiawei Shen, Jianjun Meng, Yupeng Yang, fan zhang, Xinglong Gong, Tian Xue
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Cell Press
Verified
Multidiscipline Therapy: Cervicofacial Vascular Anomaly With Macroglossia, Maxillofacial Deformity
Conflicts of Interest The authors declare no conflicts of interest. References 1 and , “Congenital Vascular and Lymphatic Diseases,” Circulation Research 135, no. 1 (2024): 159–173. 2 and , “Venous Malformations in Childhood: Clinical, Histopathological and Genetics Update,” Dermatopathology 8, no. 4 (2021): 477–493, https://doi.org/10.3390/dermatopathology8040050.
Multidiscipline Therapy: Cervicofacial Vascular Anomaly With Macroglossia, Maxillofacial Deformity
Conflicts of Interest The authors declare no conflicts of interest. References 1 and , “Congenital Vascular and Lymphatic Diseases,” Circulation Research 135, no. 1 (2024): 159–173. 2 and , “Venous Malformations in Childhood: Clinical, Histopathological and Genetics Update,” Dermatopathology 8, no. 4 (2021): 477–493, https://doi.org/10.3390/dermatopathology8040050.
Security finite‐time H∞ output tracking control for unmanned aerial vehicles under denial‐of‐service attack
This paper focuses on addressing the challenges of finite-time output tracking control for unmanned aerial vehicles (UAVs) with a particular emphasis on security concerns. The potential impact of denial-of-service (DoS) attacks on the integrity of measurement-to-control communication channels is incorporated into our analysis.
Clarification of the Clinical Characteristics of Autoimmune Disease-Related Ulcers to Improve Treatment Outcomes: A Retrospective Study
Skip to main content Intended for healthcare professionals Skip to main content Get full access to this article View all access and purchase options for this article. References 1. Suzuki E, Kyozuka H, Nishida T, Kanno T, Ohira H. Systemic lupus erythematosus, complicated with refractory skin ulcers, treated successfully with bosentan. Mod Rheumatol. 2009;19(4):447-451. 2. Wang L, Wang FS, Gershwin ME. Human autoimmune diseases: A comprehensive update. J Intern Med. 2015;278(4):369-395. 3.
Numerical Investigation of Droplet Impact on Stationary and Horizontal Moving Surfaces with Superhydrophobic Micro-Pillar Structures
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Upregulation of Receptor Interacting Protein 1 Induced by UVB Contributes to Photodamage of the Skin Through NF‐κB Pathway In Vivo and In Vitro
1 Introduction There are direct or indirect induction of DNA damages, production of reactive oxygen species, and activation of signaling pathways of inflammation and apoptosis involved in the molecular mechanisms of UV-induced skin photodamage [1, 2]. The NF-κB pathway, which has been widely documented, plays a key role and eventually is activated in the inflammatory response of photodamage of the skin induced by UV [3, 4].
Physics-Informed Fractional-Order Recurrent Neural Network for Fast Battery Degradation with Vehicle Charging Snippets
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Manganese Cobalt Sulfide-Doped Fibrous Sulfurized Polyacrylonitrile for High-Rate and Long-Life Lithium-Sulfur Batteries
Manganese Cobalt Sulfide-Doped Fibrous Sulfurized Polyacrylonitrile for High-Rate and Long-Life Lithium-Sulfur Batteries Sulfurized polyacrylonitrile (SPAN) is regarded as a promising cathode material for next-generation lithium batteries. However, the insufficient electronic and ionic conductivity of the SPAN material leads to low rate-performance, unsatisfied utilization of active materials, and limited cycling stability.
Outcomes and risk factors for cardiac surgery during pregnancy: a 13-year, two-centre, retrospective cohort study
Have a website account?Log In orRegister for exclusive website content. Home / Vol 16, No 11 (November 30, 2024) / Outcomes and risk factors for cardiac surgery during pregnancy: a 13-year, two-centre, retrospective cohort study
Inflation Disagreement Weakens the Power of Monetary Policy
Skip to main content The Federal Reserve, the central bank of the United States, provides the nation with a safe, flexible, and stable monetary and financial system. Sections Search Search Submit Button
Association Between Sleep Quality and Duration During Pregnancy and Risk of Infant Being Small for Gestational Age: Prospective Birth Cohort Study
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Placenta Thickness Mediates the Association Between AKIP1 Methylation in Maternal Peripheral Blood and Full-Term Small for Gestational Age Neonates
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
5-Fluorouracil combined with CalliSphere drug-eluting beads or conventional transarterial chemoembolization for unresectable hepatocellular carcinoma: a propensity score weighting analysis | Scientific Reports
Abstract This study aimed to assess the effectiveness and safety of 5-Fluorouracil (5-Fu) combined with conventional transarterial chemoembolization (cTACE) compared to 5-Fu combined with drug-eluting bead transarterial chemoembolization (DEB-TACE) using CalliSpheres for the treatment of unresectable hepatocellular carcinoma (HCC) using propensity score weighting methods.
Informal Institution and Tourism Development: Insights From Confucian Culture
Conflicts of Interest The authors declare no conflicts of interest. References , , and . 2022. “Radical and Incremental Innovation: The Roles of Firms, Managers, and Innovators.” American Economic Journal: Macroeconomics 14, no. 3: 199–249. https://doi.org/10.1257/mac.20170410. , , and . 2011. “Innovation in the Tourism Industry: The Case of Tourism@.” Tourism Management 32, no. 5: 1204–1213. https://doi.org/10.1016/j.tourman.2010.08.010. , and . 2015.
Coupling High‐Entropy Core with Rh Shell for Efficient pH‐Universal Hydrogen Evolution
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202403353-sup-0001-SuppMat.docx9.5 MB Supporting Information References 1, , Elect. Eng. Jpn. 2014, 186, 20. 2, , , , , , , , Nat. Commun. 2021, 12, 6776. 3, , , , , , Adv. Mater. 2021, 33, 2007100. 4, , , Nat. Rev. Chem. 2017, 1, 0003. 5, , , Adv. Energy Mater. 2020, 10, 2002453. 6, , , , , , , J. Electrochem. Soc. 2005, 152, J23. 7, J. Electroanal. Chem. 1972, 39, 163. 8, , , Nat. Rev. Chem. 2017, 1, 1.
Widely Targeted Metabolomics Analysis to Reveal Metabolite of Morus alba L. in Different Medicinal Parts
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Correction: V-Doping coupled H2O2 pre-oxidation synergistically promote NiCo-LDH for urea oxidation-assisted hydrogen production
Correction: V-Doping coupled H2O2 pre-oxidation synergistically promote NiCo-LDH for urea oxidation-assisted hydrogen production Correction for ‘V-Doping coupled H2O2 pre-oxidation synergistically promote NiCo-LDH for urea oxidation-assisted hydrogen production’ by Jiawei Guo et al., J. Mater. Chem. A, 2024, https://doi.org/10.1039/D4TA01763C. This article is Open Access This article has not yet been cited.
Adaptive urban traffic signal control based on enhanced deep reinforcement learning - Scientific Reports
Abstract One of the focal points in the field of intelligent transportation is the intelligent control of traffic signals (TS), aimed at enhancing the efficiency of urban road networks through specific algorithms. Deep Reinforcement Learning (DRL) algorithms have become mainstream, yet they suffer from inefficient training sample selection, leading to slow convergence. Additionally, enhancing model robustness is crucial for adapting to diverse traffic conditions.
CEBPB as a potential biomarker for prognosis and immuneinfiltration in clear cell renal cell carcinoma
Abstract Clear cell renal cell carcinoma (ccRCC) is an aggressive kidney cancer subtype with poor prognosis.This study explores the expression and clinical significance of the CCAAT/enhancer-binding protein beta CEBPBgene in ccRCC. RNA sequencing, gene amplification, and mutation data were sourced from TCGA, UCSC XENA, and cBioPortal. Data processing involved the STAR workflow and R software for statistical analysis and visualization.
Tau Protein Accumulation Trajectory-Based Brain Age Prediction in the Alzheimer’s Disease Continuum
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Photosensitizing Metal Covalent Organic Framework with Fast Charge Transfer Dynamics for Efficient CO2 Photoreduction
Photosensitizing Metal Covalent Organic Framework with Fast Charge Transfer Dynamics for Efficient CO2 Photoreduction Designing artificial photocatalysts for CO2 reduction is challenging, mainly due to the intrinsic difficulty for multiple functional units to cooperate efficiently.
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