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Articles by Ryan Wang
Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract GATA2 (GATA binding protein 2) deficiency is a severe immunodeficiency caused by heterozygous variants in the gene encoding the transcription factor GATA2. Ex vivo gene editing of a patient’s own CD34+ hematopoietic stem and progenitor cells (HSPCs) could provide curative treatment.
Assessment of upper-limb motor recovery after stroke using a wrist-worn accelerometer digital biomarker
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Existing clinical assessments for upper-limb motor rehabilitation poststroke pose limitations as end points for efficient clinical trials.
A single-dose topical therapy cures scabies in a human-relevant porcine model
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Scabies affects ∼400 million people annually, yet current therapies lack ovicidal activity, require repeat dosing, and are increasingly compromised by treatment failure and resistance.
Cranial bone marrow–derived monocytes promote neuroinflammation in chronic traumatic brain injury
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Patients with chronic traumatic brain injury (cTBI) experience long-term exacerbated neurological decline, which is even more severe in older patients, yet the underlying mechanisms remain unclear.
Hyperosmotic niche adaptation and tissue polyamines underlie MRSA persistence in the kidney
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Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia causes substantial morbidity, but tissue reservoirs that permit bacterial persistence remain poorly defined.
By Ryan Wang, Sílvia Puigarnau Coma, Jonas Wolff, Nobuhiro Kanazawa, Caroline Martens, Segewkal Heruye, Amy Zollman, Jered Myslinski, Annabelle White, Chetan Poudel, Farooq Syed, Bernhard Maier, Bill Bowen, Tarek M. El-Achkar, Patrick McGuire, Patrick Mcguire, FANG FANG, Yunlong Liu, Juexin Wang, Tomohiko Ai, Taeok Bae, Shinichi Makino, Jodi Yanagida, Yinghua Cheng, Kyle McCrocklin, Kazuya Hirakochi
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Science Magazine
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FAK inhibitor and RAF/MEK clamp avutometinib enhance KRAS G12C inhibitor efficacy in preclinical models of non–small cell lung cancer
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract KRAS G12C (Gly12→Cys) inhibitors (G12Cis) have improved outcomes for patients with KRAS G12C–mutated non–small cell lung cancer (NSCLC), but their clinical benefit is limited by the emergence of resistance mechanisms.
What is agentic workforce management?
A real-time analyst spots an adherence miss and messages the agent. A planner pulls historical volumes to build next quarter's staffing plan. A scheduler opens a spreadsheet to balance coverage against fairness rules. This is how workforce management has worked for 30 years and every step still requires a human to notice something before anything happens. Agentic workforce management changes that model.
Welllinkchip Deploys Three-Tier Inspection Protocol to Combat Counterfeit Electronic Components
HONG KONG, June 16, 2026 /EINPresswire.com/ -- WELL LINK CHIPS GROUP CO., LIMITED, an independent distributor of electronic components, has deployed a three-tier quality control system to detect and eliminate counterfeit and refurbished parts from customer supply chains.
The death of college exploration
If you read my application to Yale, you would probably guess that I spent my bright college years flitting between economic research seminars, physics labs and a political campaign office. Instead, I spent my first week of classes grinding through applications for the Yale Student Investment Group or the Yale Undergraduate Consulting Group. By the end of sophomore year, I had climbed the ranks of the consulting group and was running its client acquisition team.
Why The Impact Of AI On Customer Support Isn’t What Leaders Expected
Ryan Wang, Cofounder and CEO, Assembled. In 2024 and 2025, the headlines were relentless: AI would eliminate customer service jobs. CFOs began modeling aggressive headcount reductions. Boards asked when the contact center would finally become “agentless.” The assumption was straightforward: If AI could resolve tickets, it would naturally replace human support teams entirely. In 2026, the reality on the ground looks far more nuanced.
Is AI going to kill customer support jobs?
Ryan Wang|Published 32 minutes ago A few months ago, I walked into the office of one of our customers, a publicly traded vertical software company with tens of thousands of small business customers. I expected to meet a traditional support team with rows of agents on the phones, sitting at computers triaging tickets. Instead, it looked more like a control room. There were specialists monitoring dashboards, tuningAIbehaviour, debugging API failures, and iterating on knowledge workflows.
La IA no mató la atención al cliente; la está reconstruyendo
Hace unos meses, entré en la oficina de uno de nuestros clientes, una empresa de software vertical que cotiza en bolsa y cuenta con decenas de miles de pequeñas empresas. Esperaba encontrarme con un equipo de soporte tradicional con filas de agentes al teléfono, sentados frente a computadoras, clasificando tickets. En cambio, parecía más bien una sala de control.
AI didn’t kill customer support. It’s rebuilding it
A few months ago, I walked into the office of one of our customers, a publicly traded vertical software company with tens of thousands of small business customers. I expected to meet a traditional support team with rows of agents on the phones, sitting at computers triaging tickets. Instead, it looked more like a control room. There were specialists monitoring dashboards, tuning AI behavior, debugging API failures, and iterating on knowledge workflows.
AI didn't kill customer support. It's rebuilding it
11 hours ago OpenAI, the company behind DALL-E, Sora, and ChatGPT, has been on a tear lately. Its new Sora app, a combination of an AI video generator and a social media platform, was released late last year to mass fanfare and more than a little panic, anger, and consternation. And then hot on its heels came …
Why Brands Will Fire Their "AI-Only" Strategies In 2026
Ryan Wang, Cofounder and CEO, Assembled. On a recent trip to Dallas, I sat next to a customer support agent who was trying to help a customer resolve a payment issue. They had five tabs open, three systems up and were piecing together an answer in real time, bouncing between dashboards, internal docs and chat logs just to understand what had happened. It was this perfect illustration of both how fragmented the job can be and how much human judgment it actually requires.
Inovação com IA é aprimorar trabalho e não cortar empregos | Fast Company Brasil
Em 2017, quando eu era engenheiro na Stripe, sugeri um sistema de machine learning que poderia reduzir a equipe de suporte pela metade. Achei que estava resolvendo o maior custo da empresa: as pessoas. Afinal, não é esse o objetivo da automação? A resposta da chefe de suporte me pegou de surpresa: “parabéns. Você automatizou a parte fácil.” Foi nesse momento que percebi: o problema real não eram os profissionais, mas o fluxo de trabalho. Os agentes precisavam alternar entre 10 ferramentas diferentes.
automatizar no es suficiente para transformar
Cuando era ingeniero en Stripe, allá por 2017, presenté un sistema de aprendizaje automático que reduciría nuestra plantilla de soporte a la mitad. Pensé que solucionaba el mayor coste de la empresa: el personal. Al fin y al cabo, ¿no es ese el objetivo de la automatización? La respuesta del jefe de soporte me pilló desprevenido: “Felicidades. Has automatizado la parte fácil”. Me di cuenta de que el verdadero problema era el flujo de trabajo. Los agentes alternaban entre diez herramientas diferentes.
Good AI innovation means focusing on workflow not cutting jobs
The network confirmed it is "indefinitely" pulling the show. Disney’s ABC said Wednesday it has pulled “Jimmy Kimmel Live!” off the air “indefinitely” following the late-night host’s comments Monday about the motivations of the man who authorities say fatally shot conservative activist Charlie …
Former Amazon Engineer Announces Private Beta of AI-Powered Personal Assistant
Former Amazon Engineer Announces Private Beta of AI-Powered Personal Assistant Daxtr introduces a proactive AI sidekick that handles daily tasks via SMS and redefines consumer AI monetization through intent.
Lessons Learned @ MLH Fellowship - Production Engineering Track
Background As a University student with only a barebones understanding of fullstack development, I've always relied on managed platforms like vercel or netlify to help deploy my projects. And while I've always been curious as to how CI/CD works, the opportunity to learn never really presented itself. At least, not until recently. 7 weeks ago, I started my journey in this summer's cohort in the Production Engineering track @ MLH and I've learned so much since then.
Rapid Assessment of Relative Hemolysis Amidst Input Uncertainties in Laminar Flow
This version is not peer-reviewed. Nasim Gholizadeh,Ryan Wang,Gayatri Gautham,Gautham Krishnamoorthy * Nasim Gholizadeh,Ryan Wang,Gayatri Gautham,Gautham Krishnamoorthy * This version is not peer-reviewed.
Is It Time to Replace Plasma With Prothrombin Complex Concentrate in Cardiac Surgery?
Bleeding after cardiac surgery with cardiopulmonary bypass is associated with adverse clinical outcomes and increased resource utilization. Broadly speaking, this bleeding can be due to inadequate surgical hemostasis or microvascular bleeding caused by bypass-induced platelet dysfunction and/or depletion of coagulation factors.
Is It Time to Replace Plasma With Prothrombin Complex Concentrate in Cardiac Surgery?
Bleeding after cardiac surgery with cardiopulmonary bypass is associated with adverse clinical outcomes and increased resource utilization. Broadly speaking, this bleeding can be due to inadequate surgical hemostasis or microvascular bleeding caused by bypass-induced platelet dysfunction and/or depletion of coagulation factors.
In-hospital outcomes following surgery versus conservative therapy in elderly patients with C2 fractures: a propensity score-matched analysis
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Asystolic donor warm ischemia time is associated with development of postreperfusion syndrome in donation after circulatory death liver transplant
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request.
Controlled formation of ball-milled carbon quantum dots via optimized graphite structures by numerical simulation
Controlled formation of ball-milled carbon quantum dots via optimized graphite structures by numerical simulation Carbon quantum dots (CQDs) have been widely employed in various applications. Till present, the mechanical ball milling method for synthesizing CQDs from coal is considered as one promising approach towards scalable fabrications. However, the exact formation mechanism as well as the kinetic process of CQDs from ball milling remain ambiguous.
Drop the shortcuts: image augmentation improves fairness and decreases AI detection of race and other demographics from medical images
Research in context We used Google Scholar and PubMed search engines to do our review. We used keywords “Fairness”, “Shortcut learning”, “Machine learning in healthcare”, and “Medical image” to query the articles on Google Scholar. We used the following terms “(((disparity OR bias OR fairness OR shortcuts) AND (classification)) AND ((x-ray) OR (MRI))) AND (machine learning [MeSH Terms] OR deep learning [MeSH Terms])” on PubMed. We limited the articles to original research and English articles.
With border hypocrisy, GOP demonstrates unwavering loyalty to Trump
U.S. President Joe Biden and former U.S. President Donald Trump visited the United States’ southern border on Feb. 29 to highlight their respective solutions for America’s immigration crisis. This visit followed Capitol Hill’s latest immigration-related debacle: Senate Republicans blocked a border security bill that included most of their own demands on Feb. 7.
Machine Learning in R: An Application Using CDC Data
Utilizing machine learning and Centers for Disease Control and Prevention (CDC) data, we addressed the challenge of diagnosing heart disease, the leading cause of death worldwide. We programmed six models using R to predict whether patients have coronary heart disease using information relating to their lifestyle, demographics, and medical records. The models diagnosed patients with ~%80 accuracy and 0.7 F1-score.
Safety and efficacy of intrathecal baclofen trials for the treatment of hypertonia: a retrospective cohort study
Correspondence Jeffrey S. Raskin: Ann & Robert H. Lurie Children’s Hospital, Chicago, IL. jraskin@luriechildrens.org. INCLUDE WHEN CITING Published online December 8, 2023; DOI: 10.3171/2023.11.PEDS23473. Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. *S.A. and V.J.H. contributed equally to this work.
Vivek Ramaswamy’s charisma is nonsensical and dangerous
Republican Party presidential candidate Vivek Ramaswamy perfectly represents our current political climate’s downward spiral. Ramaswamy, 38, is a multimillionaire and former biopharmaceutical executive who is currently campaigning for the Republican presidential nomination without any previous political experience.
Acoustically-Targeted Measurement of Transgene Expression in the Brain
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Girls Cross Country Roundup: West High Finishes Third at MVC Valley Divisional
Photo by Rob Howe Roundups/ West High Ryan MurkenFollow @rmmurkenCindy Wang, Gabby Moniza, Girls Cross Country, West HighOctober 14, 2021 Your Prep Sports Cindy Wang finished fourth to help West High to a third-place team finish on Thursday at the Mississippi Valley Conference Valley Divisional meet at Kickers Soccer Complex in Iowa City. Wang was fourth in a time of 20:05 to lead a trio of West High runners in the top 15 as the Trojans finished with 64 points.
West High Surprises, Impresses With Team Title at Cedar Rapids Invitational
Ryan Murken Your Prep Sports CEDAR RAPIDS – West High has all the makings of a team that could surprise at the state cross country meet next month. On Thursday the youthful Trojans surprised even themselves. Sophomores Cindy Wang and Gabby Moniza posted top-10 finishes to lift Class 4A No. 16 West High to the team title at the 17-team Cedar Rapids Invitational at Seminole Valley Park.
5 Essential Things You Need to Understand to Learn GIS
Geographic Information Systems (GIS) are an amazing tool for our jobs, career opportunities, and studies. But, most people are having a hard time learning them. Over the years, I have come to realize that there are specific things that we struggle with. In this article, we will see what they are and how we can better understand them to develop our knowledge in GIS. There are two basic types of data in GIS — vector and raster. Vector data are geometries.
IgA nephropathy after pembrolizumab therapy for mesothelioma
IgA nephropathy after pembrolizumab therapy for mesothelioma Ryan Wang1, Tathagata Das1 and Anna Takou2 1Medical Oncology, Weston Park Hospital, Sheffield, UK 2Histopathology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK Correspondence to Dr Ryan Wang; ryan.wang{at}nhs.net Abstract The use of immune checkpoint inhibitors (CPIs), such as pembrolizumab, for the treatment of cancer, is now prevalent.
Magnetic-field-induced energy bandgap reduction of a perovskite by spin-orbit coupling via a low strength magnet
Magnetic-field-induced energy bandgap reduction of a perovskite by spin-orbit coupling via a low strength magnet Broad impact may be anticipated when an energy bandgap is varied substantially by a small change of the physical environment.
A Lightweight Distributed Scheduled Jobs Resource Coordination Solution
In projects, it is often necessary to use scheduled jobs to do some business. In the JAVA world, commonly used open-source distributed scheduled job frameworks are: 1. Quartz 2. Spring Batch Quartz and Spring Batch are very powerful, however, they just need multiple database tables to support the entire business. For a simple scheduled job application, they are a bit heavy. This article will introduce a lightweight, Redis-based resource coordination for distributed schedule jobs.
Pyrrolidinium containing perovskites of thermal stability and water resistance for photovoltaics
Pyrrolidinium containing perovskites of thermal stability and water resistance for photovoltaics Alex Fan Xu, Ryan Taoran Wang, Wenjuan Yang, Gu Xu, Ray Lapierre and Nebile Isik Gaktas Abstract The commonly employed methyl-ammonium containing perovskites are unstable at high temperature or under moisture attack, thus limiting their commercial applications.
Pyrrolidinium lead iodide from crystallography: a new perovskite with low bandgap and good water resistance
Pyrrolidinium lead iodide from crystallography: a new perovskite with low bandgap and good water resistance The crystal structure of a new perovskite material, (C4H8NH)PbI3 was determined and illustrated by single crystal X-ray diffraction. UV spectra, photoluminescence and XRD results show it is a promising alternative to hybrid organic–inorganic perovskites due to it's good water resistance and suitable bandgap. You have access to this article Please wait while we load your content...
A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network
In planar cell polarity (PCP), the epithelial cells are polarized along the plane of the cell surface perpendicular to the classical apical–basal axis, a process mediated by several conserved signaling receptors. Two PCP-signaling proteins, VANGL planar cell polarity protein 2 (Vangl2) and Frizzled6 (Fzd6), are located asymmetrically on opposite boundaries of the cell.
A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network
In planar cell polarity (PCP), the epithelial cells are polarized along the plane of the cell surface perpendicular to the classical apical-basal axis, a process mediated by several conserved signaling receptors. Two PCP-signaling proteins, VANGL planar cell-polarity protein 2 (Vangl2) and Frizzled6 (Fzd6), are located asymmetrically on opposite boundaries of the cell.
Self-standing electrodes with core-shell structures for high-performance supercapacitors
He, G; Ling, M; Han, X; Abou El Amaiem, DI; Shao, Y; Li, Y; Li, W; He, G; Ling, M; Han, X; Abou El Amaiem, DI; Shao, Y; Li, Y; Li, W; Ji, S; Li, B; Lu, Y; Zou, R; Ryan Wang, F; Brett, DJL; Xiao Guo, Z; Blackman, C; Parkin, IP; - view fewer (2017) Self-standing electrodes with core-shell structures for high-performance supercapacitors. Energy Storage Materials , 9 pp. 119-125. 10.1016/j.ensm.2017.07.005. (In press). Full text not available from this repository.
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