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Articles by Mei Wang
Cervical cancer screening willingness and associated health beliefs among predominantly college-educated young women attending gynecology clinics in Shenzhen, China
Abstract Purpose: This study examined cervical cancer screening willingness and its associations with Health Belief Model (HBM) constructs among predominantly college-educated young women attending gynecology outpatient clinics in Shenzhen, China. Methods: A cross-sectional convenience-sampling survey was conducted (May 2023–May 2026) among 2,317 young women recruited from gynecology outpatient clinics in Shenzhen, China.
Cross-scale genetic, molecular, and cellular triangulation prioritizes ACSL5 as a T3-responsive candidate linking hypothyroidism liability to anemia
Abstract Purpose: Anemia is a recognized complication of hypothyroidism, but disease-level genetic studies have not identified a clear erythroid cell-intrinsic target. We integrated genetic validation, molecular-QTL prioritization, and replicated triiodothyronine (T3)-responsive erythroid experiments to identify candidates linking hypothyroidism liability to anemia. Materials and methods: Two-sample Mendelian randomization (MR) assessed genetically predicted hypothyroidism and anemia.
Perceived community cervical cancer prevention support and cervical cancer screening utilization among women in Shenzhen, China: a cross-sectional study
Abstract Purpose: Community health services have the capacity to inform eligible women about cervical cancer prevention, recommend screening, and assist with access to care. Whether favorable perceptions of community support are associated with completed screening in an urban Chinese setting is unclear.
Integrated multi-omics reveals mycelial spatial restructuring and coordinated metabolic reprogramming underlying fungal iron detoxification in Leucocalocybe mongolica
Abstract Global soil contamination with heavy metals threatens food security and ecosystem health. This study investigates the potential of saprotrophic fungus Leucocalocybe mongolica (LY9) to immobilize and detoxify iron. Soil amendment with LY9 reduces iron bioavailability in a dose-dependent manner, with the 50% treatment decreasing soil iron by 28.3%.
Radical enantioconvergent meta-C─H alkylation of pyridines
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Enantioselective meta-C─H functionalization of pyridines represents a long-standing challenge that, if resolved, would open transformative avenues in synthesis and drug discovery.
Integrated multi-omics analysis identifies a senescence-associated myeloid transcriptional program in acute myocardial infarction
Abstract Acute myocardial infarction (AMI) triggers extensive immune activation that critically contributes to cardiac injury and post-infarction remodeling. Although senescence-associated molecular programs have been increasingly implicated in cardiovascular disease, their cellular distribution and systemic immune relevance in AMI remain incompletely understood. Herein, we use multi-omics analyses to identify a myeloid-centered senescence-associated program in AMI.
Unraveling the Synergistic Catalysis Effect in MOF-Based Photocatalysts
1 Introduction The development of efficient and stable photocatalytic systems for the conversion of solar energy into chemical energy, such as hydrogen, carbon-based fuels, and high-value-added organic compounds, represents a promising pathway for alleviating global energy crisis [1-5]. This endeavor holds crucial strategic significance for establishing a clean, low-carbon, and sustainable energy system [6-9].
Associations of nutrition knowledge and healthy lifestyle with body mass index status among medical students: a cross-sectional study
Abstract Objectives: To examine the associations of nutrition knowledge and healthy lifestyle score (HLS) with body mass index (BMI) status among medical students. Methods: This cross-sectional study included 1,040 medical students from Yangzhou University, China. Participants were recruited using convenience sampling and completed an online questionnaire. BMI was calculated using self-reported height and weight and classified as underweight, normal weight, or overweight/obesity.
Sources of reproductive health information and their associations with self-reported contraceptive familiarity and education needs among female college students: a cross-sectional study in China
Abstract Purpose:: Female college students (FCSs) obtain reproductive health information from multiple sources. Although the Internet has become a major channel for health information seeking, the relationship between information source, contraceptive familiarity, and education needs remains unclear. This study examined primary information sources and their associations with self-reported contraceptive familiarity and education needs in a multi-province sample.
Lactoferrin ameliorates non-alcoholic fatty liver disease by modulating hepatic sensitivity to fibroblast growth factor 21
Abstract Lactoferrin (LF) exerts beneficial effects in against various metabolic disorders including nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the effect of LF supplementation on hepatic sensitivity to fibroblast growth factor 21 (FGF21) in NAFLD and further elucidate the underlying molecular mechanisms. We found that LF supplementation significantly ameliorated glucose and lipid metabolic disorders, and attenuated hepatic steatosis in mice fed a high-fat diet (HFD).
Chronic low-grade inflammation drives skeletal aging and neurocognitive decline: inflammaging as a central hub coupling bone–brain aging
Abstract Background: Global population aging has driven a marked rise in the co-prevalence of osteoporosis and cognitive impairment, and a bidirectional epidemiological association between the two conditions is now supported by multiple meta-analyses. The shared biological mechanisms underlying this comorbidity, however, remain incompletely defined, and the two disorders continue to be managed within largely separate clinical disciplines.
Racial differences in lifetime healthcare costs associated with obesity-related multimorbidity among the U.S. population aged 40 years or older
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Limited discriminant validity of health belief and 3C models in high HPV vaccine coverage settings: the moderating role of hukou and structural barriers
Abstract Background: Whether traditional health belief models (HBM) and 3C models can distinguish residual non-vaccinators in settings with >70% HPV vaccine coverage is unknown. The moderating role of China’s household registration (hukou) on psychological factors and behavior has rarely been quantified. Methods: From April 2025 to February 2026, we surveyed 1,257 women aged 18–65 from six Shenzhen communities.
Mobility-aware predictive task offloading using deep reinforcement learning for future 6G-inspired vehicular networks
Abstract Reliable communication and ultra-low latency data processing are essential requirements for emerging Internet of Vehicles (IoV) applications such as cooperative autonomous driving, augmented reality navigation, and real-time safety monitoring.
Willingness to receive cross-border human papillomavirus vaccination among Chinese male university students: a cross-sectional study with statistical indirect-association analysis
Abstract Background: Human papillomavirus (HPV) vaccination is an important strategy for preventing HPV-related disease among males. Access to male HPV vaccination may involve cross-border health seeking for some university students in mainland China.
Association between diabetic control and progression of monoclonal gammopathy of undetermined significance to multiple myeloma
Abstract Diabetes Mellitus (DM) is a risk factor for multiple myeloma (MM), but the relationship between diabetic control and risk of progression to MM in patients with monoclonal gammopathy of undetermined significant (MGUS) is unclear. We conducted a retrospective cohort study of US Veterans diagnosed with MGUS from 10/1/1999-12/31/2023 with prior DM. MGUS and MM diagnoses were confirmed using published natural language processing-assisted models.
Computer Science > Cryptography and Security
Semantic search systems map data to a high-dimensional vector space and support retrieval of similar data via approximate nearest neighbor search. When the system is hosted by a trusted cloud provider, there is no privacy for the data or the query. Our goal is to design a system with three properties: privacy, accuracy, and efficiency.
Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism
Main text (Cell Metabolism 32, 1052–1062.e1–e8; December 1, 2020) In the original version of this article, the authors inadvertently misused the representative immunofluorescence image of WT-1 (green) for the Cre+/Jaml+/+ control group (left panel) in Figure 2E during the figure compilation. This error does not affect the results or conclusions of the paper. The authors sincerely apologize for any confusion that the oversight may have caused.
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleJuly 12, 2026 Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance Click to copy article linkArticle link copied! Mei Wang Mei Wang Department of Medicinal Chemistry, State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, Shandong Basic Science Special Academic Zone (Pharmacy), School of...
Development and Validation of a Prognostic Model for Cervical Cancer Based on Chlamydia trachomatis -Associated Transcriptional Signatures
Abstract Background Chlamydia trachomatis (CT) infection has been identified as an independent predictor of risk of cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC); however, its prognostic relevance and molecular mechanisms remain poorly understood. Therefore, we aimed to construct a CESC prognostic model based on genes associated with CT infection. Methods Transcriptomic data were obtained from GEO and TCGA databases.
Realization of the Bienenstock-Cooper-Munro rule in a single memristor
Abstract Neuromorphic computing aims to build electronic systems that mimic the brain’s remarkable efficiency and adaptability. A key feature of brain is homeostatic plasticity, which stabilizes neural activity; the Bienenstock–Cooper–Munro (BCM) rule accurately describes this by adjusting a neuron’s sensitivity threshold based on past activity. However, implementing the homeostatic rule in synaptic device remains challenging.
In vivo engineering tumor cells to a universal “all-in-one” cancer vaccine with full antigen spectrum
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Cancer vaccines offer a promising strategy to initiate de novo T cell responses or enhance existing ones, either functioning independently or synergizing with T cell–modulating therapeutics to reduce tumor burden.
Diagnostic value of cardiovascular biomarkers for cerebral–cardiac syndrome risk in acute ischemic stroke
Abstract Background: Cerebral–cardiac syndrome (CCS) is a complication commonly observed following an ischemic stroke, which results in increased morbidity and mortality. Timely diagnosis of CCS is of prognostic significance. This study investigates the significance of multiple cardiovascular biomarkers for CCS in patients with acute ischemic stroke (AIS).
Topological Semimetal Co 3 Sn 2 S 2 for Visible-Light Driven Photoelectrocatalytic Water Splitting Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! The development of highly efficient, low-cost photoelectrocatalytic (PEC) water splitting catalysts is crucial for addressing energy consumption and environmental pollution issues. Topological semimetals (TSMs), owing to their unique band structure, high carrier mobility, and excellent intrinsic stability, are considered as promising PEC catalysts.
Characterization and Identification of Potential Allergenic Proteins in Sophora japonica L. Pollen Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleJune 15, 2026 Characterization and Identification of Potential Allergenic Proteins in Sophora japonica L.
Integrins as key regulators in tumor perineural invasion: mechanisms and clinical implications
Perineural invasion (PNI) serves as an important prognostic indicator in various solid tumors, closely associated with tumor recurrence and reduced survival rates. At present, the molecular mechanisms of initiating PNI have been extensively studied but still lack targets employed for efficient diagnosis and treatment clinically.
Fairy Ring Fungus Rewires Rice Lipid Metabolism: A Symbiotic Strategy for Enhanced Growth and Photosynthetic Efficiency
1 Introduction Rice (Oryza sativa) is one of the most significant staple food crops worldwide, serving as a primary dietary component for approximately 50% of the global population (Asma et al. 2023). Ensuring sustainable rice production systems is therefore critical for global food security. Despite continuous efforts to increase productivity over recent decades, rice yield improvements have remained limited despite significant applications of chemical fertilizers (Peng et al. 2006).
Three Meroterpenes From the Mangrove Endophytic Fungus Phyllosticta sp. E2A1
1 Introduction Meroterpenoids are a group of hybrid natural products derived from both terpene and non-terpene biosynthetic origins [1, 2]. In the past twenty years, hundreds of meroterpenoids with diverse skeletons have been identified from fungi, marine organisms, and bacteria [1, 3, 4]. Meroterpenoids exhibit a wide range of bioactivities, such as antibacterial [5], anti-inflammatory [6, 7], lipid-lowering [8], cytotoxic [9], and BACE1-inhibitory activities [10].
Association of the platelet-to-albumin ratio with diabetic nephropathy lesions via a fine-tuning-free large language model framework
Abstract Objective: The current research aims to utilize a fine-tuning-free, freely available large language model (LLM) framework to systematically investigate the correlation between the platelet-to-albumin ratio (PAR) and the pathological severity of diabetic nephropathy (DN). This approach aims to develop an exploratory risk stratification tool for this microvascular complication. Methods: A retrospective analysis was conducted on 195 patients diagnosed with DN.
Study on the Association Between the Systemic Immune-Inflammation Index and Polycystic Ovary Syndrome in Women Undergoing in vitro Fertilization for Subfertility
Introduction Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age, which is characterized by abnormal menstruation, ovarian polycystic changes, and hyperandrogenism.1 It is often accompanied by insulin resistance, obesity, and increased cardiometabolic risk,2 which seriously impair the patient’s reproductive health and long-term quality of life.3–5 Due to its complex etiology and high heterogeneity of clinical manifestations, the...
Bridging the Gap between In Vitro and Intracellular: Systematic Analysis and Screening Optimization of Inconsistencies between Target Activity and Cellular-Level Activity Click to copy article link Article link copied!
Experimental Technical Artifacts Colloidal Aggregation Hydrophobic small molecules self-assemble to form particles, which nonspecifically adsorb and chelate target proteins, reducing the effective concentration of free targets 1. Detergent (Triton X-100) antagonism experiment; 2. Dynamic light scattering to detect colloidal particles; 3. Centrifugal precipitation verification; 4.
Comprehensive analysis of microbiome and transcriptome revealed the mechanisms of Flammulina velutipes stem-base enhance intestinal health in Gymnocypris eckloni
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. REFERENCES (2016). The zebrafish as a model to study intestinal inflammation. Developmental and Comparative Immunology, 64, 82–92. , , , , , , , , , & (2021).
Global Burden and Drivers of Cutaneous Malignant Melanoma Among Women Aged 55 and Older
Back to Journals » International Journal of Women's Health » Volume 18 Authors Wang M Received 7 May 2026 Accepted for publication 25 July 2026 Published 14 August 2026 Volume 2026:18 622573 DOI https://doi.org/10.2147/IJWH.S622573 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Matteo Frigerio Mei Wang Department of Dermatology and Venereology, The Affiliated Yangming Hospital of Ningbo University, Ningbo,...
ELMO2 is a therapeutic vulnerability in mesenchymal-like and drug-resistant non-small cell lung cancer
Abstract Epithelial-mesenchymal transition drives tumor metastasis and therapeutic resistance, yet few treatments have been developed that target this process. Here, we show that ELMO2 represents a specific vulnerability in mesenchymal-like cells. ELMO2 suppression induces excessive autophagy and cell death via FAK activity inhibition. We identify ELMO3 as a functional paralog that compensates for ELMO2 loss, establishing a synthetic lethal interaction.
Maintenance-event-constrained vibration health index for degradation assessment of a mine main fan
1. Introduction Underground mines increasingly operate at large scale and high intensity, placing stringent demands on the reliability of ventilation systems. The main mine ventilation fan is the critical asset that delivers fresh air to underground workings, dilutes toxic and explosive gases, and controls dust concentrations in return airways [1].
Comprehensive Genomics and Functional Validation Reveal Evolutionary Insights into Xanthan Gum Biosynthesis and Pathogenesis of Xanthomonas campestris pv. campestris Click to copy article link Article link copied!
Introduction Click to copy section linkSection link copied! Xanthomonas campestris pv. campestris (Xcc), a Gram-negative bacterium, is a devastating phytopathogen responsible for black rot disease in economically significant cruciferous crops worldwide. Additionally, it serves as the primary microorganism for the industrial production of xanthan gum, a versatile exopolysaccharide (EPS). As a pathogen, Xcc infects a wide range of Brassica species and related plants.
Leveraging patient-reported outcomes and serum markers to predict active ulcerative colitis: a multicenter cohort
Abstract Background and aim: This study aims to develop a score system via noninvasive and reliable clinical tools for individuals to distinguish remission and active Ulcerative Colitis (UC). Methods: We performed a retrospective multicenter study collecting 173 patients in the training cohort and 124 patients in the validation cohort with UC. Then we assessed the relationship between patient-reported outcomes (PROs) and serum indicators with endoscopic disease activity (defined as UCEIS ≥1).
Associations of four insulin resistance indicators with subsequent pregnancy outcomes in women with recurrent pregnancy loss
Abstract Aims: This study investigated the associations of four insulin resistance (IR) indicators—the triglyceride-glucose (TyG) index, the TyG-body mass index (TyG-BMI), the metabolic score for IR (METS-IR), and the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio—with subsequent pregnancy outcomes in women with recurrent pregnancy loss (RPL) and assessed their predictive value. Methods: This cohort study recruited RPL participants from the Chinese Pregnancy Loss Cohort.
Development and Validation of a Prognostic Model for Cervical Cancer Based on Chlamydia trachomatis -Associated Transcriptional Signatures
Back to Journals » International Journal of Women's Health » Volume 18 Authors Wang M , Xiong S , Qiu X, Hu Z, Xie L , Zhao H, You C Received 24 March 2026 Accepted for publication 16 June 2026 Published 9 July 2026 Volume 2026:18 611743 DOI https://doi.org/10.2147/IJWH.S611743 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Vinay Kumar Mei Wang,1,* Shiyin Xiong,2,* Xiufeng Qiu,2 Zhengrui Hu,3 Lang Xie,4...
Synergistic Impact of Obesity and PCOS on Immune Dysregulation: A Review of Systemic and Local Inflammatory Profiles
Back to Journals » International Journal of Women's Health » Volume 18 Authors Li H, Wang M, Chen X, Guan H, Zhao J, Song H, Song J, Tang H, Tang L Received 23 March 2026 Accepted for publication 18 May 2026 Published 25 May 2026 Volume 2026:18 611363 DOI https://doi.org/10.2147/IJWH.S611363 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Matteo Frigerio Hui Li,* Mei Wang,* Xu Chen, Huijuan Guan, Jiahui...
Quantifying the contribution of modifiable risk factors for progression of MGUS to multiple myeloma in a Veteran population
aHR multivariable-adjusted hazard ratio AO Agent Orange aPAF multivariable-adjusted population attributable fraction BMI body mass index CCI Charlson Comorbidity Index CI confidence interval CIF cumulative incidence function Ig immunoglobulin IQR interquartile range M- monoclonal MGUS monoclonal gammopathy of undetermined significance MM multiple myeloma NLP natural language processing TCDD 2,3,7,8-tetrachlorodibenzo-p-dioxin VHA Veterans Health Administration 1 INTRODUCTION Multiple myeloma...
Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema
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Keywords rosacea oxoglutaric acid OXGR1 cryo-EM vasodilation Get full text access Log in, subscribe or purchase for full access. References 1. Gether, L. ∙ Overgaard, L.K. ∙ Egeberg, A. ... Incidence and prevalence of rosacea: a systematic review and meta-analysis Br. J. Dermatol. 2018; 179:282-289 2. Aksoy, B. ∙ Altaykan-Hapa, A. ∙ Egemen, D. ... The impact of rosacea on quality of life: effects of demographic and clinical characteristics and various treatment modalities Br. J. Dermatol. 2010; 163:719-725 3.
By Wenqin Xiao, Yan Zhu, Xinjie Jonathan Tang, Kongkai Zhu, Weifeng Zhang, Mengting Chen, Kui Cai, Zheng Wu, Mei Wang, JIAYI LIU, Zixin Tan, Zhixiang Zhao, Yan Tang, Yingxue Huang, Ben Wang, Fangfen Liu, Qian Wang, Fan Yang, Dan Jian, Wei Shi, Hongfu Xie, Xiang Chen, Lulu guo, Zhili Deng, Jinpeng Sun, Ji Li, San Xu, Linglong Long, Aike Wu, Songqi Zhou
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Impact Factors and Policy Effectiveness of Renewable Energy Generation in China: Insights from a Multi-Scenario Bayesian Analysis
Submitted: 26 February 2026 You are already at the latest version This study develops a hybrid analytical framework that bridges data-driven K2 structural learning with expert-informed Bayesian Networks to decrypt the intricate interdependencies among policy instruments, resource endowments, and socio-economic variables across China’s hydropower, wind, and solar power.
Correction to “Phenotypic Screening: A Cornerstone Engine for Discovering Original Anti-Infective Drugs”
The authors offer their sincere apologies for the errors identified in the original references of this article. Specifically, in the initial draft of the manuscript, references were presented in the format of “the first three authors et al.”, and a thorough verification has confirmed that the information pertaining to the first three authors, title, journal, year, volume, issue, page is entirely accurate and error-free.
C═C Double Bond Cleavage of 2-Cyanoaryl Acrylamides for the Construction of 3-Hydroxyquinoline-2,4(1H,3H)-diones
Cite Jump to ExpandCollapse ArticleJanuary 26, 2026 C═C Double Bond Cleavage of 2-Cyanoaryl Acrylamides for the Construction of 3-Hydroxyquinoline-2,4(1H,3H)-diones Click to copy article linkArticle link copied! Jia Hu Jia Hu Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China Tai-Gang Fan Tai-Gang Fan Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R.
Adherence to healthy dietary patterns and risk of premature aging in adult survivors of childhood cancer in the St. Jude Lifetime Cohort Study
CONFLICT OF INTEREST STATEMENT The authors declare that they have no competing interests. DATA AVAILABILITY STATEMENT Data can be obtained on request. Requests should be directed to the St. Jude LIFE (https://sjlife.stjude.org/), which has a protocol for approving data requests. Supporting Information Filename Description cncr70246-sup-0001-suppl-data.pdf274.8 KB Supplementary Material REFERENCES 1, , , et al.
Heterostructures Coupling with Oxygen Vacancies Enable High Performance V2O3/Zn3V3O8@C Cathode for Aqueous Zinc‐Ion Batteries
Conflicts of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available in the supplementary material of this article.
Relationship between dietary protein intake and prevalence of sarcopenia in older adults
Abstract Objective: To assess the relationship between sarcopenia and dietary protein use among adults. Method: The retrospective, cross-sectional study was conducted after approval from the ethics review committee of Sichuan Province Orthopaedic Hospital, China, and comprised prospective data of American adults aged at least 20 years who had participated in the National Health and Nutrition Examination Survey between 2015 and 2018.
Salusin α Counteracts Salusin β to Attenuate Artery Medial Calcification through the Inhibition of Oxidative Stress and ERK Signaling Pathway in Rats with Chronic Kidney Disease
ArticleArticles in Press103793 1Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China 2National Demonstration Center, Nanjing Medical University, Nanjing 210000, China 3Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China Publication History: Received October 6, 2025; Revised December 3, 2025; Accepted December 8, 2025; Published online December 15, 2025 DOI: 10.1016/j.jpet.2025.103793 External LinkAlso...
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