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Articles by Ming Jin
Repulsive guidance molecule-a regulates neutrophil-associated Th17 responses in CNS autoimmunity
Abstract Background and aim: Repulsive guidance molecule-A (RGMa) is well-known for its roles in T-cell-mediated neuroinflammation and CNS repair. Innate-adaptive immune interactions, particularly between neutrophils and Th17 cells, are emerging as critical drivers of neuroinflammatory pathology in multiple sclerosis (MS). Whether RGMa regulates these neutrophil-associated Th17 responses remains largely unknown. Elucidating this mechanism may reveal novel therapeutic targets for MS.
Preconception Blood Pressure and Sex of the Baby: A Large Prospective Cohort Study in China
1 Introduction The prediction of baby's sex before pregnancy period has long been a hot public topic since ancient times till present. A declining proportion of male births in industrialized countries (United States, Canada, Denmark, Netherlands) over the past several decades has been queried as a possible health indicator in the world [1].
Tuina for chronic fatigue syndrome: study protocol for a randomized controlled trial integrating tryptophan metabolism, gut microbiota, and brain network alterations
Abstract Background: Chronic fatigue syndrome (CFS) is a disabling multisystem disorder characterized by persistent fatigue, post-exertional malaise, unrefreshing sleep, and neurocognitive and gastrointestinal symptoms. Effective non-pharmacological treatments remain limited. Increasing evidence suggests that CFS involves not only peripheral metabolic and gastrointestinal abnormalities but also central nervous system dysfunction.
DuoFlow-KG: a dual-modal evidence retrieval framework for high-density LLM-augmented KGQA
Abstract Knowledge Graph Question Answering has increasingly adopted a retrieval-reasoning decoupling paradigm, where large language models synthesize answers based on retrieved evidence subgraphs. However, existing retrieval methods often fail to jointly optimize semantic relevance and structural dependencies, resulting in fragmented evidence or search space explosion in multi-hop reasoning.
The immunosuppressive tumor microenvironment in glioblastoma
Abstract Glioblastoma (GBM) remains one of the most lethal primary brain tumors, with limited therapeutic improvement despite maximal surgical resection, radiotherapy, and temozolomide. A major barrier to durable treatment response is the profoundly immunosuppressive tumor microenvironment, which is characterized by immune exclusion, defective antigen presentation, myeloid dominance, and severe T-cell dysfunction.
From molecular networks to translational intervention: current progress in the mechanisms of gemcitabine resistance in bladder cancer
Abstract Bladder cancer remains one of the most common malignancies of the urinary tract. Although the treatment landscape has expanded rapidly in recent years, gemcitabine still occupies a central position in intravesical treatment for non-muscle-invasive bladder cancer, in perioperative systemic therapy for muscle-invasive disease, and in platinum-based first-line regimens for advanced urothelial carcinoma.
Mamba for Time Series Analysis: A Contemporary Survey
You are already at the latest version Time series analysis (TSA)–forecasting, anomaly detection, imputation, classification, and unified multi-task analytics– has become a battleground for sequence-modeling backbones, where Transformers, MLPs, convolutions, and state-space models compete on long context benchmarks.
ANXA11 suppression restores muscular function in the mdx mouse model of Duchenne muscular dystrophy (DMD)
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Abstract A critical question in Duchenne muscular dystrophy (DMD) research is whether regulatory mechanisms beyond dystrophin loss contribute to impaired muscle regeneration. Through integrative analysis of proteomics and single-nucleus RNA sequencing database, we identify the upregulation of ANXA11, a gene encoding a Ca²⁺-dependent phospholipid-binding protein, in MYH3⁺ regenerative myofibers from both mdx mice and DMD patients.
By Wen Tang, Bowen Lin, Ming Jin, Tianzhen Liu, Jingyi Zhou, Yanhong Jin, Yi Chen, Yanan Zhu, Ping Ping Hu, Chengyong Shen, Zhuoxian Meng, Guoping Peng, Liqun Lei, Xingxu Huang, Chenxiao Zhang, Ke Chen, Guiheng Zhang, Xufeng Yang, Xue Wei Lv, Adrien Rousseau, Jian Yang, Zhi-Ying Wu, Ge Bai, Zhen Zhong, Gonglu Liu
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Nature
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Traditional Chinese medicine nursing competency and its correlates among clinical nurses in Guangyuan City, China
Abstract Objective: To assess Traditional Chinese Medicine (TCM) nursing competency among clinical nurses in Guangyuan City, China, and identify associated factors to inform targeted training and management. Methods: A cross-sectional survey was conducted from January to October 2024. Using multistage stratified cluster sampling, clinical nurses were recruited from 20 public medical institutions in Guangyuan City.
Efficient integrated quantum memory for light - Nature Photonics
Abstract Scalable implementation of quantum networks and photonic processors demands integrated photonic memories with high efficiency, yet current integrated systems have been limited to storage efficiencies below 27.8%.
Visible-Light-Catalyzed Cascade Radical Cyclization for 3-Substituted Chroman-4-ones
Cite Jump to ExpandCollapse ArticleNovember 17, 2025 Visible-Light-Catalyzed Cascade Radical Cyclization for 3-Substituted Chroman-4-ones Click to copy article linkArticle link copied! Jie Xie Jie Xie Department of Polymer Materials, School of Materials Science and Engineering, Tongji university, 4800 Caoan Road, Shanghai 201804, P. R. China Jie Hou Jie Hou Department of Polymer Materials, School of Materials Science and Engineering, Tongji university, 4800 Caoan Road, Shanghai 201804, P. R.
Dialect diversity and regional financial development
ABSTRACT Finance plays a pivotal role in modern economies, and studying the factors influencing regional financial development is meaningful. Focusing on 253 prefecture-level cities from 2003 to 2018 in China, this study examines the impact of dialect diversity on regional financial development from an informal institutional perspective.
07.15.25 -- The FDA Was Darned Near Perfect, Right?
The PDA Regulatory Conference 2025 Achieving CGMP Excellence: Sustainable Compliance Across the Lifecycle continues its 34-year tradition of delivering impactful content that supports the development and implementation of effective quality systems across the product lifecycle. This premier pharmaceutical CGMP conference on 08-10 September 2025 in Washington, DC will focus on strategies to manage manufacturing and quality risks while driving operational excellence and sustainable compliance.
A Hybrid Electromagnetic Algorithm for Reconstructing 2‐D Dielectric Objects Based on the M‐Net
Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Interaction Between Starch Expansion and Gluten Network Formation Enhances the Texture of Noodles: The Cooperation of Synergy During Processing and Antagonism During Cooking
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description jtxs70031-sup-0001-Supplementary_material.docxWord 2007 document , 18.8 KB Data S1. References , , , et al. 2020. “Evaluation of the Processing Quality of Noodle Dough Containing a High Tartary Buckwheat Flour Content Through Texture Analysis.” Journal of Texture Studies 51, no. 4: 688–697. https://doi.org/10.1111/jtxs.12539. , , , , and . 2024.
Impact of Voxelotor on Red Blood Cell Exchange Therapeutic Procedures: Evaluation of Multi‐Institutional Procedure Data
1 Introduction Sickle cell disease (SCD) affects approximately 100 000 people in the U.S. Caused by a single amino acid substitution in the β hemoglobin gene, normal hemoglobin A is changed to hemoglobin S (HbS). HbS polymerization leads to sickled, rigid red blood cells (RBC) which produce chronic hemolysis and end organ damage [1].
SS‐LDP: A Framework for Sparse Streaming Data Collection Based on Local Differential Privacy
Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts
1 Introduction Cardiac fibrosis, which is characterized by the transition of myofibroblasts from fibroblasts and excessive deposition of the extracellular matrix (ECM), is considered the major driver of adverse cardiac remodeling and progressive dysfunction in many heart diseases, including myocardial infarction (MI), chronic ischemic cardiomyopathy, genetic cardiomyopathies, and so on[1, 2] It is widely known that cardiac fibrosis is a complex networking process involving many cellular and...
LLMs Can Plan Only If We Tell Them
Papers Abstract Large language models (LLMs) have demonstrated significant capabilities in natural language processing and reasoning, yet their effectiveness in autonomous planning has been under debate. While existing studies have utilized LLMs with external feedback mechanisms or in controlled environments for planning, these approaches often involve substantial computational and development resources due to the requirement for careful design and iterative backprompting.
Novel View Synthesis with Depth Priors Using Neural Radiance Fields and CycleGAN with Attention Transformer
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Full article: Efficacy and Safety of Lenvatinib Plus Programmed Death-1 Inhibitors with or Without Transarterial Chemoembolization in the Treatment of Unresectable Hepatocellular Carcinoma
Abstract Purpose Transarterial chemoembolization (TACE) is recommended as a standard therapy for intermediate-stage hepatocellular carcinoma (HCC) and is the most widely used first-line treatment for advanced HCC. This study aimed to evaluate the clinical benefits and tolerability of TACE added to a combination of lenvatinib and programmed death-1 (PD-1) inhibitor in patients with unresectable HCC (uHCC).
Deep-Eutectic-Solvent-Decorated Metal-Organic Framework for Food and Environmental Sample Preparation
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Machine Learning-Assisted Surface-Enhanced Raman Spectroscopy Detection for Environmental Applications: A Review
1. Introduction Click to copy section linkSection link copied! Comprehensive environmental monitoring, spanning wastewater, drinking water, surface water, and air quality, has the potential for early detection of contaminants and pollutants. (1) Increased integration of public health and environmental monitoring is essential for safeguarding health, preserving ecosystems, and upholding regulatory standards.
Earlier Age at Menopause, Plasma Metabolome, and Risk of Premature Mortality
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Silybin Meglumine Mitigates CCl4-Induced Liver Fibrosis and Bile Acid Metabolism Alterations
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Optimizing Rural Highway Maintenance Scheme with Mathematical Programming
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High-coherence parallelization in integrated photonics - Nature Communications
Abstract Coherent optics has profoundly impacted diverse applications ranging from communications, LiDAR to quantum computations. However, developing coherent systems in integrated photonics comes at great expense in hardware integration and energy efficiency. Here we demonstrate a high-coherence parallelization strategy for advanced integrated coherent systems at minimal cost.
[2409.02689] Frequency-domain Parallel Computing Using Single On-Chip Nonlinear Acoustic-wave Device
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Monitoring Soybean Soil Moisture Content Based on UAV Multispectral and Thermal-Infrared Remote-Sensing Information Fusion
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Asiaticoside enhances the effect of propofol on the invasion, ferroptosis and immune escape of bladder cancer
REFERENCES (2023). Asiaticoside increases Caspase-9 activity in MCF-7 cells and inhibits TNF-α and IL-6 expression in nude mouse xenografts via the NF-κB pathway. Molecules, 28, 2101. https://doi.org/10.3390/molecules28052101 , , , , , , , , , & (2023). Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review. Journal of Cellular and Molecular Medicine, 27, 593–608. https://doi.org/10.1111/jcmm.17635 , , , , , , , , , , , , , & (2014).
DyG-Mamba: Continuous State Space Modeling on Dynamic Graphs
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Asynchronous Holocene lake evolution in arid mid-latitude Asia is driven by glacial meltwater and variations in Westerlies and the East Asian summer monsoon
Understanding the mechanisms driving hydrological change in arid Central Asia over a range of time scales is crucial for making predictions for future changes in fragile desert-lake ecosystems. As of yet, the drivers of hydrological changes in lake systems of arid Central Asia over the Holocene remain largely unexplored.
Joint association and interaction of birth weight and lifestyle with hypertension: A cohort study in UK Biobank
1 INTRODUCTION Hypertension has been one of the most common chronic noncommunicable diseases.
High-Order Wideband Band-Pass Miniaturized Frequency-Selective Surface with Enhanced Equivalent Inductance
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma
Background: SLC20A1, a prominent biomarker in several cancers, has been understudied in its predictive role in head and neck squamous cell carcinoma (HNSCC). Methods: The Cancer Genome Atlas (TCGA) database was used to analyze HNSCC prognosis, SLC20A1 overexpression, and clinical characteristics. Quantitative real-time PCR and Western blot analysis confirmed SLC20A1 expression in HNSCC tissues.
Triethyl Amine as an Effective Reducing Agent for Sulfoxide Deoxygenation
Triethyl Amine as an Effective Reducing Agent for Sulfoxide Deoxygenation Enabled by triehtyl amine (Et3N) and thionyl chloride (SOCl2), an efficient and practical protocol for deoxygenation of sulfoxide to sulfide was developed. This new method features a wide range of scopes, including diaryl, dialkyl and aryl alkyl substituted sulfoxides. Detialed mechanistic investigations reveal the crucial role played by Et3N as an electron-donating reductant rather than the hydrogen-atom donor.
Enhanced C‐To‐T and A‐To‐G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED (Adv. Sci. 3/2024)
Graphical Abstract Mitochondrial DNA Base Editing In article number 2304113, Yinghui Wei and co-workers successfully improve the targeting scope, efficiency, and specificity of mitochondrial DNA base editing by fusing a single-stranded deaminase (xAID) and the nuclear export signal sequence. This study offers a useful tool with broad applicability for therapy in mitochondrial genetic diseases.
Dual-Level Framework for OpenBIM-Enabled Design Collaboration
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Ming Jin 1,2,* and Baizhan Li 1 1 Joint International Research Laboratory of Green Buildings and Built Environments (Ministry of Education), Chongqing University, Chongqing 400045, China 2 China Southwest Architectural Design and Research Institute Corp. Ltd., Chengdu 610041, China * Author to whom correspondence should be addressed.
Resource and Energy Utilization of Swine Wastewater Treatment: Recent Progress and Future Directions
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Motion limiting nonlinear dynamics and frequency characteristics of pipes reinforced with carbon nanotube agglomerations coupled with piezoelectric actuator
Motion limiting nonlinear dynamics and frequency characteristics of pipes reinforced with carbon nanotube agglomerations coupled with piezoelectric actuator Autores: Ming Jin Localización: Mechanics based design of structures and machines, ISSN 1539-7734, Vol. 51, Nº. 11, 2023, págs.
Enhanced C‐To‐T and A‐To‐G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED
1 Introduction Mutations in mitochondrial DNA (mtDNA) could result in severe diseases with different penetrance, presentation, and prognosis affecting at least 1 in 4300 individuals.[1, 2] Tools for introducing specific modifications into mtDNA are urgently needed to both model and potentially treat these diseases.
A closed form solution for uniformly loaded rectangular plates with adjacent edges clamped and the two others simply supported (CCSS)
In this paper, a closed form solution is proposed on bending of uniformly loaded rectangular plates with adjacent edges clamped and the two others simply supported (CCSS). Deflection surface can be expressed by a double sine series referred to as Navier solution. Numerical results of deflection, bending moments agree with existing solutions including solutions of finite element model (FEM).
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