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Emily Wilson on Muck Rack

Emily Wilson

Verified
Ireland
As seen in: ITV News, Nature, MDPI, Substack, The Conversation, The Globe and Mail, Channel 4 News, JAMA (The Journal of the American Medical Association), Journal of Intensive Care, Salon, Women's Health and
Head of UK News, ITV News. Formerly: Bureau of Investigative Journalism, Channel 4 News and BBC News. Scot, mother, wife of harmonica player.
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Articles

RNA-triggered cell killing with CRISPR–Cas12a2

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By Paul Scholz, Jared Thompson, Kadin T. Crosby, Nathan M. Krah, Robin Back, Rebekka Medert, Christian Zurek, Oleg Dmytrenko, Emily Wilson Verified, Jared Rutter, Xiaoyang Zhang, Michael Krohn, Ryan Jackson, Yang Liu Verified, Torsten Fauth, Grant Schlauderaff, Zachary A. Berkheimer, Alivia Jolley, Dirk Sombroek, Friso T. Schut
| Nature Verified
Abstract Selectively eradicating target cells on the basis of their genetic or transcriptional identity remains important in basic research, medicine, biotechnology and agriculture1,2,3. For applications involving bacteria, CRISPR nucleases offer promising options due to their ability to enact RNA-guided counterselection4,5,6,7; however, using these same nucleases for counterselection in eukaryotes has proven much more restrictive8,9,10,11,12,13,14.
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Rapid activation of ARF6 after RAF inhibition augments BRAF V600E and promotes therapy resistance

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By Junhua Wang, Yinshen Wee, Thomas Jacob, Aaron Rogers, Deja M. Brooks, Prachi Gupta, Emily Wilson Verified, tong liu, Eric Smith, michael davies, Martin McMahon, martin mcmahon, Sheri Holmen, Robert L. Judson-Torres, Roger Wolff, Allie H. Grossmann, Lise. K. Sorensen, Joshua K. H. Tay, YN Vashisht Gopal
| Nature Verified
Abstract The intrinsic ability of cancer cells to evade death underpins tumorigenesis, progression, metastasis, and the survival of drug-tolerant persister (DTP) cells. Herein, we discovered that the small GTPase ARF6 plays a central role in tumor survival by fortifying RAF oncoprotein levels. ARF6 activation was sufficient to increase BRAFV600E, ARAF, and CRAF proteins through a post-transcriptional mechanism, while sustained inhibition of ARF6 eventually led to decay.
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EWSR1::ATF1 Orchestrates the Clear Cell Sarcoma Transcriptome in Human Tumors and a Mouse Genetic Model

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By Benjamin B. Ozenberger, Emily Wilson Verified, Alexander J. Lazar, Jared J Barrott
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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