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Articles by Jun Ni
An amygdala-mediated simulation-to-decision cascade aligns interbrain dynamics to solve social dilemmas
Abstract Mutual cooperation (MC) requires independent decision-makers to coordinate under uncertainty about each other’s intentions. Using simultaneous intracranial electroencephalography from epilepsy–patient dyads playing a real-time iterated prisoner’s dilemma, we identified neurocognitive mechanisms that enable interacting brains to align during mutual cooperation.
Modelling and control of all-wheel omnidirectional independent steering vehicle: a filtered tube-based MPC approach for simultaneous tracking of lateral position and heading angle
An all-wheel omni-directional independent steering vehicle (AWOISV) is a specialised all-wheel independent steering vehicle with each wheel capable of steering up to , enabling unique manoeuvres like yaw and diagonal movement.
Extensive pneumocephalus in a fatal central nervous system infection caused by NDM-1–producing carbapenem-resistant Klebsiella pneumoniae : a case report
Abstract Background: Central nervous system (CNS) infections caused by New Delhi metallo-β-lactamase-1 (NDM-1)-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) are rare but associated with extremely high mortality because of extensive antimicrobial resistance and poor blood–brain barrier (BBB) penetration. To the best of our knowledge, there have been no published reports of pneumocephalus associated with infection caused by NDM-1-producing K. pneumoniae.
Computer Science > Machine Learning
Predictive models over structured electronic health records (EHRs) remain central to machine learning for healthcare, but few have jointly emphasized quantitative laboratory information and interpretability with respect to input medical events.
STK40 inhibits profibrotic Arg1 + macrophage differentiation and renal fibrosis by regulating poly-ubiquitination of STAT3
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Abstract Monocyte-derived macrophages are central drivers of chronic renal inflammation and fibrosis, yet the regulatory mechanisms that restrain their profibrotic differentiation remain poorly defined. Here, we identified serine/threonine kinase 40 (STK40) as a suppressor of profibrotic macrophage differentiation and renal fibrosis progression. Myeloid-specific Stk40 deletion exacerbated renal fibrosis in multiple mouse models.
By Jun Ni, Jia Li, Jia-min Liu, Xin Li Verified, Xi-Yu Liu, Zhe Ji, Hui-Yao Lan, Dan-Dan Zhang, Si-ying Sun, Zhen-yan Jiang, Yue-xiao Tao, Hui-zi Wang, Ge-ge He, Xue-zhu Li, Xue-feng Wu
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Nature
Verified
Computer Science > Computer Vision and Pattern Recognition
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Effectiveness of preoperative pulmonary rehabilitation in patients with lung cancer combined with moderate to severe COPD: study protocol for a randomized controlled trial
Keywords Preoperative pulmonary rehabilitation aerobic exercise preoperative rehabilitation education COPD Lung cancer surgery Post-operative complication incidence Get full text access Log in, subscribe or purchase for full access. References 1. Martín-Sánchez, J.C. ∙ Lunet, N. ∙ González-Marrón, A. ... Projections in Breast and Lung Cancer Mortality among Women: A Bayesian Analysis of 52 Countries Worldwide Cancer Res. 2018; 78(15):4436-4442 2. Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC.
Targeting TMED4 enhances CD8 + T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Endoplasmic reticulum stress (ERS) and autophagy regulate tumor-infiltrating T cell function and exhaustion, but the underlying mechanisms remain unclear.
Solar-driven biosynthesis of chemicals from phosphite-rich wastewater and carbon dioxide
Abstract Solar-driven biosynthesis from carbon dioxide can facilitate sustainable chemical manufacturing. However, cell-density limits and contamination susceptibility have seriously hampered its practical implementation. Here we develop a solar–chemical hybrid-driven biosynthesis (SCHB) strategy integrating wastewater-based phosphorus recovery into biological photosynthetic metabolism for chemical production.
CLWD: a Chinese histopathology dataset for lung adenocarcinoma subtype classification - Scientific Data
Abstract Effective diagnosis and treatment of lung adenocarcinoma depends on accurate typing, subtyping, and grading. Herein, we present the CLWD dataset, a valuable resource for the lung cancer pathology community, comprising 408 whole-slide images (WSIs) from 210 patients specifically curated for the study of lung adenocarcinoma subtypes. Scanned at 80 × magnification, it is one of the largest datasets in Asia, with a particular emphasis on Chinese patient demographics.
All you need to know about the Chinese Year Of The Red Horse
Updated / Monday, 16 Feb 2026 15:54 Horse-shaped lantern installation on display during the China Qinhuai Lantern Festival as the Spring Festival approaches in Nanjing, Jiangsu Province of China. Photo: VCG/VCG via Getty Images Analysis: Horses held immense importance historically in ancient China and are a powerful cultural symbol of loyalty, endurance and dedication Chinese New Year falls on February 17th 2026 marking the arrival of the Year of the Horse.
Multi-objective partitioning and cooperative peak shaving for distributed photovoltaic clusters via multi-agent reinforcement learning
1Wuxi Power Supply Company of State Grid Jiangsu Electric Power Co., Ltd., Wuxi, China 2Jiangsu Frontier Electric Technology Co., Ltd., Nanjing, China 3State Grid Jiangsu Electric Power Co., Ltd., Nanjing, China Introduction: To address the urgent need for enhanced grid flexibility in high-penetration distributed photovoltaic (PV) systems, this paper proposes a novel two-stage framework integrating multi-objective cluster partitioning and multi-agent reinforcement learning (MARL) for...
Transcranial alternating current stimulation for treating spinocerebellar ataxia type 3: A randomized controlled trial
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Keywords spinocerebellar ataxia type 3 non-invasive brain stimulation transcranial alternating current stimulation randomized sham-controlled trial functional connectivity Introduction Spinocerebellar ataxia type 3 (SCA3), caused by a pathogenic Cytosine-Adenine-Guanine (CAG) expansion of the ATXN3 gene, is the most common autosomal dominant form of inherited ataxia worldwide.1,2 Also known as Machado-Joseph disease, the core clinical manifestation of SCA3 is progressive cerebellar ataxia,...
By Xinyuan Chen, Xia Liu, Wei Lin, Lin Zhang, XiaoPing Cheng, Ziqiang Huang, Wanli Zhang, Huating Zeng, Yingjuan Zhang, Mengcheng Li, Shuna Huang, Zhaodi Wang, Xichen Wang, Zhenyi Liu, Xuanyu Chen, Bi Shane Cheng, Yue Zhang, Qunlin Chen, Duolao Wang, Jun Ni, Ning WANG, Ying Fu, Yanhua Lian, Naping Chen, Ruying Yuan, Zhixian Ye, Shirui Gan
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Cell Reports Medicine
Verified
Enhanced Oil Recovery Mechanism Mediated by Reduced Miscibility Pressure Using Hydrocarbon-Degrading Bacteria During CO2 Flooding in Tight Oil Reservoirs
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Research and Development of an IoT Smart Irrigation System for Farmland Based on LoRa and Edge Computing
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Rational multienzyme architecture design with iMARS
Keywords biocatalysis multienzyme assembly synthetic biology biomanufacturing fusion enzyme scaffold complex PET biodegradation Introduction Biocatalysis plays a pivotal role in green chemistry and in the pharmaceutical industry, which is currently advancing from single-enzyme conversion to multienzyme cascades for complicated catalytic routes.1,2,3,4,5,6,7,8,9 The spatial organization of natural multienzyme complexes is often precisely controlled to create a direct path between sequential...
Innovative coupling pathway for second- and third-generation biomass: Efficient L-lactate synthesis from xylose and C1 compounds
Effective carbon emission reduction strategies are required to address global climate change.[1] Biomass energy, owing to its renewable nature and low environmental impact, has emerged as a key solution to the need for sustainable energy production. The current development of biomass energy focuses on the sustainable use of non-food biomass, with second-generation and third-generation biomass resources being the primary research focus.
Unveiling the Microscopic Origins and Thermoelectric Performance of full-Heusler compounds K2RbSb and Rb2KSb
Unveiling the Microscopic Origins and Thermoelectric Performance of full-Heusler compounds K2RbSb and Rb2KSb This study systematically investigates the thermal transport properties of the full-Heusler compounds K2RbSb and Rb2KSb using self-consistent phonon theory and the Boltzmann transport equation. The results show that the strong anharmonicity and four phonon scattering of alkali metal atoms result in extremely low lattice thermal conductivity (κL) for these compounds.
Anomalous phonon transport and thermoelectric properties in honeycomb compounds ACuTe (A = Na, K, Rb)
Anomalous phonon transport and thermoelectric properties in honeycomb compounds ACuTe (A = Na, K, Rb) Developing materials with low thermal conductivity is crucial for practical applications such as thermoelectrics, and this requires a deep understanding of phonon transport. Typically, weak chemical bonding, heavy atomic masses, and complex structures are common features of high-performance thermoelectric materials with low lattice thermal conductivity (κL).
Fractional CO2 Laser to Treat Surgical Scars: A System Review and Meta‐Analysis on Optimal Timing
1 Introduction Surgical scars represent a natural part of the wound healing process, where fibrous tissue replaces normal skin following injury [1, 2]. While many scars resolve over time, some can manifest as hypertrophic or keloid scars, causing discomfort and disfigurement for patients [3, 4]. Laser therapies, notably fractional CO2 laser treatments, have emerged as promising interventions to soften and flatten these scars, offering relief from symptoms such as pain and itching [5, 6].
Machine Learning Advances in High-Entropy Alloys: A Mini-Review
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Yibo Sun 1,2 and Jun Ni 1,2,* 1 State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Beijing 100084, China 2 Frontier Science Center for Quantum Information, Beijing 100084, China * Author to whom correspondence should be addressed.
Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation - Nature Neuroscience
Abstract Cooperative interactions profoundly shape individual and collective behaviors of social animals. Successful cooperation requires coordinated efforts by cooperators toward collective goals. However, the underlying behavioral dynamics and neuronal mechanisms within and between cooperating brains remain largely unknown. We recorded intracranial electrophysiological signals from human pairs engaged in a cooperation game.
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders
The World Health Organization estimates that 1 in 8 people (970 million) suffer from a psychiatric disorder of some kind.1 Because of the high comorbidity between different psychiatric disorders, common genetic etiology has been suggested.2 A study comparing genetic correlations across 25 different brain disorders suggested shared genetic risk factors (pleiotropy) across psychiatric disorders.3 To investigate this further, the Psychiatric Genomics Consortium (PGC)4 conducted a...
Pharmacokinetics, pharmacodynamic, safety and tolerability of Fazamore
Introduction Insomnia, a common sleep disorder, is characterized by difficulty falling asleep and difficulty maintaining sleep.1 In recent years, the incidence of insomnia has been on the rise, with prevalence rates ranging from 35% to 50% of the adult population for insomnia symptoms, and 10–20% for insomnia disorder.2–4 To date, most hypnotic drugs mainly act on gamma-aminobutyric acid (GABA) receptor channel coupling, including barbiturates, benzodiazepines, non-benzodiazepines (such as...
Effects of phrenic nerve magnetic stimulation on respiratory function in stroke patients: study protocol for a randomised controlled trial
Methods and analysis This study will be a parallel controlled randomised trial comparing the effects of rPMS applied to the bilateral phrenic nerves in the neck with those of conventional rehabilitation for respiratory function in stroke patients. Baseline assessments will be conducted 1–3 days before initiating the intervention, and post-intervention assessments will be performed 1–3 days after the conclusion of the intervention.
TMED4 facilitates regulatory T cell suppressive function via ROS homeostasis in tumor and autoimmune mouse models
Abstract Endoplasmic reticulum stress (ERS) plays crucial roles in maintaining Treg stability and function, yet the underlying mechanism remains largely unexplored.
A Leakage Safety Discrimination Model and Method for Saline Aquifer CCS Based on Pressure Dynamics
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Influence of anharmonicity on the thermoelectric properties of alkali antimonide compounds ${M}_{3}\mathrm{Sb}$ ($M$ = $\mathrm{Na}$, $\mathrm{K}$, $\mathrm{Rb}$, $\mathrm{Cs}$)
This study systematically explores the mechanical, transport, and thermoelectric properties of the alkali antimonide compounds M3Sb (M = Na, K, Rb, Cs) using first-principles calculations and the Boltzmann transport equation. We found that considering quartic anharmonic effects leads to temperature-dependent phonons undergoing a frequency shift and overall phonon spectrum hardening, thereby increasing the phonon group velocity.
Influence of quartic anharmonicity on lattice dynamics and thermal transport properties of 16 antifluorite structures
This paper uses advanced first-principles calculation methods, combined with self-consistent phonon (SCP) theory, compressive sensing (CS) lattice dynamics, and Boltzmann transport equation (BTE), to calculate and study the lattice dynamics and phonon transport of 16 antifluorite structures.
Intracranial EEG signals disentangle multi-areal neural dynamics of vicarious pain perception - Nature Communications
Abstract Empathy enables understanding and sharing of others’ feelings. Human neuroimaging studies have identified critical brain regions supporting empathy for pain, including the anterior insula (AI), anterior cingulate (ACC), amygdala, and inferior frontal gyrus (IFG). However, to date, the precise spatio-temporal profiles of empathic neural responses and inter-regional communications remain elusive.
Self‐assembly of Polyoxometalate Clusters into Nanostructures with Different Dimensions
Self-assembly of polyoxometalate (POM) clusters offers a viable method for constructing nanostructures with tailored properties. Over the past few decades, POMs-based nanostructures of varying dimensions, such as nanowires, nanobelts, nanosheets, and other superstructures, have been constructed. Additionally, these nanostructures show broad prospects in optical, electrochemical, catalytic, and mechanical applications.
Social bonding in groups of humans selectively increases inter-status information exchange and prefrontal neural synchronization
Loading metrics Open Access Peer-reviewed Research Article Citation: Ni J, Yang J, Ma Y (2024) Social bonding in groups of humans selectively increases inter-status information exchange and prefrontal neural synchronization. PLoS Biol 22(3): e3002545. https://doi.org/10.1371/journal.pbio.3002545 Academic Editor: David Poeppel, New York University, UNITED STATES Received: August 7, 2023; Accepted: February 12, 2024; Published: March 19, 2024 Copyright: © 2024 Ni et al.
Molecules | Free Full-Text | Study on the Effect of Cations on the Surface Energy of Nano-SiO2 Particles for Oil/Gas Exploration and Development Based on the Density Functional Theory
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
All you need to know about the Chinese Year of the Dragon
Analysis: One of the most important and sacred symbols in Chinese culture, the dragon comes with rich meaning and symbolism According to the Chinese lunar calendar, the Chinese New Year falls on February 10th and it is the Year of the Dragon. The dragon holds long-standing cultural significance in China and serves as a unique spiritual icon for the Chinese nation, symbolising courage and indomitable spirit.
Melatonin sensitizes leukemia cells to the MCL1 inhibitors S63845 and A‐1210477 through multiple pathways
Supporting Information Filename Description jpi12943-sup-0001-SUPPLEMENTAL_INFORMATION_-v3.docx2.4 MB Supporting information. REFERENCES 1, , , et al. Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis. Cell Death Dis. 2016; 7:e2132. 2, , , et al. MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes. Blood. 2001; 97: 3902-3909. 3.
Study on lattice dynamics and thermal conductivity of fluorite AF2 (A = Ca, Sr, Ba) based on first principles
Study on lattice dynamics and thermal conductivity of fluorite AF2 (A = Ca, Sr, Ba) based on first principles The fluorite materials has received particular attention in electron optics due to its favorable optical properties. However, further exploration of these materials in the field of Thermoelectric (TE) is hampered by the lack of studies on the lattice thermal transport properties.
Cover Image, Volume 95, Number 12, December 2023
Corresponding Author Ronghua Jin Beijing Ditan Hospital, Capital Medical University, Beijing, China National Center for Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China Correspondence Wenhui Li, National Institute of Biological Sciences, Beijing, China.
Nasal spray of an IgM‐like ACE2 fusion protein HH‐120 prevents SARS‐CoV‐2 infection: Two investigator‐initiated postexposure prophylaxis trials
1 INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected most, if not all, people worldwide and has continuously evolved, giving rise to new variants, including the Omicron strain.
Precision Operation Technology and Intelligent Equipment in Farmland
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Interpretable Machine Learning to Discover Perovskites with High Spontaneous Polarization
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Phys. Chem. C 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Leader–follower behavioural coordination and neural synchronization during intergroup conflict - Nature Human Behaviour
Abstract Leaders can launch hostile attacks on out-groups and organize in-group defence. Whether groups settle the conflict in their favour depends, however, on whether followers align with leader’s initiatives. Yet how leader and followers coordinate during intergroup conflict remains unknown. Participants in small groups elected a leader and made costly contributions to intergroup conflict while dorsolateral prefrontal cortex (DLPFC) activity was simultaneously measured.
The effect of tDCS and TENS on poststroke shoulder pain
Back to Journals » Therapeutics and Clinical Risk Management » Volume 19 Authors Li Y, Yan ZP, Zhang NN, Ni J, Wang ZY Received 21 July 2023 Accepted for publication 18 October 2023 Published 9 November 2023 Volume 2023:19 Pages 875—887 DOI https://doi.org/10.2147/TCRM.S431816 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Deyun Wang Yu Li,1 Zhi-Peng Yan,1 Nan-Nan Zhang,1 Jun Ni,1,2 Zhi-Yong Wang1 1Department of...
High thermoelectric performance in XAgSe2 (X = Sc, Y) from strong quartic anharmonicity and multi-valley band structure
High thermoelectric performance in XAgSe2 (X = Sc, Y) from strong quartic anharmonicity and multi-valley band structure xuhao song, Yinchang Zhao, Jun Ni, Sheng Meng and Zhenhong Dai Abstract The thermal transport and thermoelectric characteristics of the chalcogenide XAgSe2 (X = Sc, Y) are comprehensively investigated through first-principles calculations.
Machines | Free Full-Text | Construction Method of Digital Twin System for Thin-Walled Workpiece Machining Error Control Based on Analysis of Machine Tool Dynamic Characteristics
1. Introduction In aerospace industry, weak rigidity thin-walled components are widely used. There are several definitions to characterize thin-wall components, and typically “thin-wall” is defined by a large ratio of wall length to wall thickens [1]. The most common thin-wall components in aviation, aerospace, and the energy industry include aircraft structural parts, impellers, and turbine blades [2].
Collective excitations of the Chern-insulator states in commensurate double moir\'e superlattices of twisted bilayer graphene on hexagonal boron nitride
Abstract We study the collective excitation modes of the Chern insulator states in magic-angle twisted bilayer graphene aligned with hexagonal boron nitride (TBG/BN) at odd integer fillings (ν) of the flat bands.
Cu2In alloy-embedded ZrO2 catalysts for efficient CO2 hydrogenation to methanol: promotion of plasma modification
Fujiao Song1, Jia Gao2, Bairen Yang1, Yan Cao1, Huanhuan Liu1 and Qi Xu2* 1Key Laboratory Under Construction for Volatile Organic Compounds Controlling of Jiangsu Province, School of Environmental Science and Engineering, Yancheng Institute of Technology, Yancheng, China 2School of Chemistry and Chemical Engineering, Jiangsu University, Zhengjiang, China Cu1In2Zr4-O-C catalysts with Cu2In alloy structure were prepared by using the sol–gel method.
Correlation of Rattlers with Thermal Transport and Thermoelectric Performance
Correlation of Rattlers with Thermal Transport and Thermoelectric Performance Aixian She, Yinchang Zhao, Jun Ni, Sheng Meng and Zhenhong Dai Abstract The presence of rattlers in the host-guest structure has sparked great interest in the field of thermoelectrics, as it allows for the suppression of thermal transport in materials through vigorous anharmonic vibrations.
A Portable Pull-Out Soil Profile Moisture Sensor Based on High-Frequency Capacitance
Open AccessArticle by Zhentao Sheng 1,2,3,4, Yaoyao Liao 1,2,3,4, Shuo Zhang 1,2,3,4, Jun Ni 1,2,3,4, Yan Zhu 1,2,3,4, Weixing Cao 1,2,3,4 and Xiaoping Jiang 1,2,3,4,* 1 College of Agriculture, Nanjing Agricultural University, Nanjing 210095, China 2 National Information Agricultural Engineering Technology Center, Nanjing 210095, China 3 Engineering Research Center of Smart Agriculture, Ministry of Education, Nanjing 210095, China 4 Jiangsu Collaborative Innovation Center for the Technology...
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