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Articles by Tao Jiang
Performance degradation and failure mechanisms of pultruded carbon/glass-fiber hybrid sucker rods after long-term downhole service
Loading metrics Open Access Peer-reviewed Research Article Citation: He D, Jiang T, Xu H (2026) Performance degradation and failure mechanisms of pultruded carbon/glass-fiber hybrid sucker rods after long-term downhole service. PLoS One 21(10): e0360408. https://doi.org/10.1371/journal.pone.0360408 Editor: Vinod Ayyappan, King Mongkut’s University of Technology North Bangkok, THAILAND Received: June 26, 2026; Accepted: September 26, 2026; Published: October 15, 2026 Copyright: © 2026 He et al.
Capturing attosecond delays in electronic and vibrational dependent photoemission of NO molecules
Abstract Timing the photoionization process reveals electron motion through the molecular potential and the interplay between electronic and nuclear dynamics. Here we show, using attosecond interferometry with high energy resolution, that photoionization delays in nitric oxide depend on the electronic state and vibrational level of the molecular ion. We observe significant delays among channels leading to different electronic states, in agreement with scattering calculations.
Cross-scale genetic, molecular, and cellular triangulation prioritizes ACSL5 as a T3-responsive candidate linking hypothyroidism liability to anemia
Abstract Purpose: Anemia is a recognized complication of hypothyroidism, but disease-level genetic studies have not identified a clear erythroid cell-intrinsic target. We integrated genetic validation, molecular-QTL prioritization, and replicated triiodothyronine (T3)-responsive erythroid experiments to identify candidates linking hypothyroidism liability to anemia. Materials and methods: Two-sample Mendelian randomization (MR) assessed genetically predicted hypothyroidism and anemia.
Comparison of sevoflurane and propofol on the novel oxygenation index and respiratory mechanics in gynecological laparoscopic surgery: a randomized controlled trial
Abstract The novel oxygenation index (NOI), which incorporates mean airway pressure (Pmean) as a key respiratory parameter, is increasingly being investigated for its enhanced ability to reflect patients’ pulmonary function compared to the traditional oxygenation index (OI). This study aimed to compare the effects of sevoflurane and propofol on the NOI in patients undergoing gynecological laparoscopic surgery in the Trendelenburg position.
Lattice light sheet activation structured illumination super-resolution microscopy
Abstract Volumetric super-resolution (SR) live imaging at high speed has been a long-standing challenge, especially in thick fluorescent specimens. Here we develop lattice light sheet activation structured illumination microscopy (LA-SIM), which integrates the advantages of superior optical sectioning and low phototoxicity offered by light sheet microscopy with SR-SIM in both linear and nonlinear schemes, using reversibly photoswitchable fluorescent protein.
SVPG: a pangenome-based structural variant detection approach and rapid augmentation of pangenome graphs with new samples
Abstract Breakthrough advances in long-read sequencing have opened unprecedented opportunities to study genetic variations through pangenome analysis, yet tools that effectively leverage such frameworks for structural variant (SV) detection remain limited. In addition, efficient construction of pangenome graphs becomes increasingly challenging with the acquisition of larger numbers of samples.
Integrated multi-omics analyses reveal the role of PAXX in colorectal cancer progression and the tumor immune microenvironment
Abstract PAXX is a DNA double-strand break repair factor involved in classical non-homologous end joining. Although elevated PAXX expression has been reported in colon cancer, its functional role and downstream mechanisms in colorectal cancer (CRC) remain incompletely defined. This study investigated the role of PAXX in CRC progression and its association with the tumor immune microenvironment.
Single-cell and spatial multi-omics combined with machine learning to unravel the heterogeneity of cholangiocarcinoma and the WFDC3-mediated prognostic regulatory mechanisms
Abstract Background: Intrahepatic cholangiocarcinoma (ICC) exhibits substantial cellular heterogeneity and a complex tumor microenvironment (TME), contributing to poor clinical outcomes. Effective prognostic biomarkers and a deeper understanding of the cellular ecosystems associated with high-risk disease remain urgently needed.
Structural Diversity Amplifies the Effects of Functional Diversity on Forest Carbon Storage Across Stand Development
1 Introduction Forests play a critical role in the global carbon cycle, and their capacity to store carbon is strongly linked to biodiversity (Pan et al. 2011). Decades of research from both experimental and observational studies show that biodiversity generally enhances ecosystem functioning, including aboveground carbon storage (AGC) (Liang et al. 2016; Isbell et al. 2011).
Author Correction: A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution
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Correction to: Nature https://doi.org/10.1038/s41586-025-09211-8 Published online 2 July 2025 In the version of this article initially published, in Extended Data Fig. 2, there was a typographical error in the figure and legend, where “Exm1-Cre” should have read “Emx1-Cre.” In the Extended Data Fig.
By Zhao Feng, Xiangning LI, Yue Luo, Xin Zhe Liu, Ben Long, Tao Jiang, Xueyan Jia, Xiaowei Sylvia Chen, Jie Luo, Xiaokang Chai, Zhen Wang, Miao Ren, Xin Lu, Gang Yao, Mengting Zhao, Yuxin Li, Zhixiang Liu, Shengda Bao, Shicheng Yang, Jiandong Zhou, Lingyi Cai, Qi Zhang, Zhengchao Xu, Siqi Chen, Wenxiang Ding, Wenjuan Shi, Hong-Wei Dong, Hui Gong, Qingming Luo, Chuhao Dou, Zoutao Zhang, Ayizuohere Tudi, Chaozhen Tan
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Nature
Verified
Research on the utilization of community health services and its determinants among older adults: a cross-sectional study in Liuzhou City
Abstract Objective: This single-center, cross-sectional study investigates the health management demands, service utilization patterns, and their determinants among the older adults in a community of Liuzhou City, to provide empirical evidence for optimizing community-based older adults health services. With rising retirement ages and the increasing proportion of older workers in China’s labor force, this study also examines how work status and schedule compatibility shape service utilization.
Phasing parental genomes of hybrid pigs facilitates the deciphering of imprinted genes and the mechanistic basis of heterosis
Abstract Conventional genetic models assume symmetric parental contributions, masking parent-of-origin effects underlying heterosis. Here, we integrate haplotype-resolved genomic and transcriptomic data from 594 F2 pigs to quantify parent-of-origin effects. We develop a phased analytical framework that overcomes the limitations of additive models, enabling systematic dissection of allelic regulatory asymmetry.
Utilizing allogeneic venous grafts to solve the problem of vascular defects and reconstruction in pancreatic surgery: a retrospective cohort study
Abstract Background: Extensive vascular invasion or defects after resection significantly limit the feasibility of radical pancreatic surgery, underscoring the value of effective vascular reconstruction techniques. This study evaluates a novel approach to vascular reconstruction using allogeneic venous grafts (AVGs) in pancreaticoduodenectomy and pancreatectomy.
Synaptic-level organization of long-range cholinergic circuits in the basal forebrain
Abstract The basal forebrain cholinergic neurons with extensive long-range projections are critical for cortical plasticity, attention, and learning. Their mesoscopic, target area-specific wiring diagram plays a pivotal role in information transfer and pathology of neurodegenerative diseases. Here, using the fluorescence micro-optical sectioning tomography (fMOST) system, the brain-wide presynaptic puncta were comprehensively mapped and reconstructed at the mesoscopic scale.
Urea transporter B–mediated urea uptake–induced protein carbamylation in platelets underlies bleeding in chronic kidney disease
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Patients with advanced chronic kidney disease (CKD) can have platelet dysfunction and consequent bleeding complications with no clear therapeutic options. Qiu et al. found that urea transporter B (UT-B), encoded by the SLC14A1 gene, may regulate bleeding in advanced CKD.
STWave: Fine-Scale Spatial Structure Discovery in Microscopic-Resolution Spatial Transcriptomics via Patchwise Wavelet Graphs
1 Introduction Spatial biology is rapidly entering the era of microscopic-resolution spatial transcriptomics ()[1], which enables whole-transcriptome mapping at subcellular resolution with unprecedented spatial precision below [2]. Next-generation ST platforms, including Visium HD [3], Xenium [4], GeoMx [5], and Stereo-seq [6], have surpassed physical resolution limits through advanced molecular barcoding and imaging-based capture strategies.
Development and Internal Validation of a Multimodal Prediction Model for Moderate-to-Severe Osteoporotic Vertebral Compression Fractures Using Bone Quality Biomarkers Derived From CT and MRI
Key words Osteoporotic vertebral compression fracture Hounsfield units Vertebral bone quality Clinical prediction model Multimodal imaging Get full text access Log in, subscribe or purchase for full access. REFERENCES 1. Wang, L. ∙ Yu, W. ∙ Yin, X. ... Prevalence of osteoporosis and fracture in China JAMA Netw Open. 2021; 4(8), e2121106 2. Lei, H. ∙ Huang, Z. ∙ Wang, F. ... Global burden of vertebral fractures from 1990 to 2021 and projections for the next three decades J Orthop Surg Res. 2025; 20(1):480 3.
Large-scale whole-genome sequencing reveals the landscape and health implications of de novo mutations
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Abstract De novo mutations (DNMs) are an important source of congenital diseases. With delayed parenthood and assisted reproductive technology (ART) use increasing, it is essential to elucidate how these reproductive factors influence DNMs and whether resulting mutations influence offspring health. Here we performed whole-genome sequencing of 24,030 individuals from 7,851 parent−offspring families, identifying 390,924 de novo single-nucleotide variants (dnSNVs).
By Na Qin, Juncheng Dai, Yue Jiang, Yuan Xie, Hong Lv, Jun L Zhou, Xiao Wang, Yangqian Jiang, Jiangbo Du, Yingjia Chen, Xianfeng Xu, Lingmin Hu, Congcong Chen, Ziye Xu, Jiawen Zhu, Yuhan Liu, Yu Wang, Ci Song, Yayun Gu, Tao Jiang, Bo Xu, Xiumei Han, Yuan Lin, Qingxia Meng, Xiufeng Ling, Hongxia Ma, Guangfu Jin, Cheng Wang, Hongbing Shen, Zhibin Hu
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Nature
Verified
Hierarchically Porous Mn-Cu Bimetallic Catalysts Derived From Dopamine-Modified ZIF for Oxygen Reduction and Zinc-Air Performance
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available in the supplementary material of this article. Supporting Information Filename Description smll74795-sup-0001-SuppMat.docx28.2 MB Supporting File: smll74795-sup-0001-SuppMat.docx. References 1, , and , “Recent Advancements in Pt and Pt-Free Catalysts for Oxygen Reduction Reaction,” Chemical Society Reviews 44, no.
Efficacy and safety of microfragmented adipose tissue versus platelet-rich plasma, hyaluronic acid and saline for knee osteoarthritis
Abstract Purpose: To compare the efficacy and safety of intra-articular microfragmented adipose tissue (MFAT) injection with platelet-rich plasma (PRP), hyaluronic acid (HA), and saline injection for knee osteoarthritis treatment. Methods: PubMed, Embase, the Cochrane Library and Web of Science were searched for randomized controlled trials (RCTs) published before April 15, 2026.
CCL20-CCR6 axis mediates mucosal-associated invariant T-M2 macrophage crosstalk to drive immune dysregulation in liver cirrhosis
Abstract Introduction: Cirrhosis is the end-stage of chronic liver disease characterized by progressive hepatic fibrosis and persistent immune dysregulation, yet the mechanisms by which immune cell crosstalk drives disease progression remain poorly understood. Methods: In the present study, we integrated bulk and single-cell transcriptomic analyses with immunofluorescence validation to investigate the role of the CCL20-CCR6 axis in MAIT cells–macrophages interactions during cirrhosis progression.
Effect and mechanism of drum axial airflow regulation on threshed-material distribution in rapeseed harvesting
[1] Kerlikowsky F, Krvger K, Hahn A, Schuchardt J P. Multi-micronutrient and omega-3 fatty acid supplementation reduces low-grade inflammation in older participants: an exploratory study. Nutrition Research, 2025. doi: 10.1016/j.nutres.2025.06.005 [2] Swanson D, Block R, Mousa S A. Omega-3 fatty acids EPA and DHA: health benefits throughout life. Advances in Nutrition, 2012; 3（1）: 1–7. [3] Grahovac N, Aleksić M, Trajkovska B, Marjanović J A, Nakov G.
Kokumi Peptides in Salt Reduction: Preparation, Evaluation Methods, Perceptual Mechanisms, and Prospects for Food Applications
Kokumi Peptides in Salt Reduction: Preparation, Evaluation Methods, Perceptual Mechanisms, and Prospects for Food Applications - Sun - 2026 - Journal of Food Science - Wiley Online Library
Dual-graph attention autoencoder for spatial domain identification in ischemic stroke
Abstract Introduction: Spatial transcriptomics enables molecular mapping of ischemic stroke tissue, but spatial domain identification is challenging when injury disrupts normal tissue geometry. Methods relying on a single spatial-proximity graph cannot connect physically distant spots that share damage-associated transcriptional programs.
Structural insights into the MLH1–FAN1 interaction reveal an uncharacterized binding interface on MLH1
Abstract Huntington’s disease is driven by CAG repeat expansion in the mutant huntingtin gene. Nuclease FAN1 and mismatch repair protein MLH1 regulate repeat expansion through direct interaction, but the underlying structural basis remains unclear. Here, we show that the MLH1 C-terminal domain binds to FAN1-derived peptides containing either the MIP or MIM motif with comparable affinities.
Luminespib and AZ5104 are effective antithrombotic drugs via targeting the platelet Ero1α-PDI pathway
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract The platelet-surface Ero1α–protein disulfide isomerase (PDI) system is essential for integrin αIIbβ3 activation and platelet aggregation. Targeting the functional interplay between Ero1α and PDI emerges as a promising antithrombotic strategy.
Ice‐Templated Three‐Dimensional Aligned Boron Nitride Nanosheets/Cellulose Nanofibers Network for High‐Performance Thermally Conductive Epoxy Composites - Li - Polymer Composites - Wiley Online Library
Tribological Applications of MoS 2 -Reinforced Polymer Composites: A Review
, , , et al., “Tribological Applications of MoS2-Reinforced Polymer Composites: A Review,” Polymer Composites (2026): 1–30, https://doi.org/10.1002/pc.71282. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Predictors of health management participation in community-dwelling older adults: a cross-sectional study based on the health belief model
Abstract Objective: This study aimed to assess the current status of health management cognition, health beliefs, and behaviors among community-dwelling older adults in Nanning, China, and to identify factors influencing their health management behaviors using the Health Belief Model (HBM). Methods: A descriptive cross-sectional study was conducted from March to June 2024. A convenience sample of 250 older adults (≥60 years) was recruited from an urban community in Nanning.
Microglial CD31 suppresses Aβ clearance and promotes Alzheimer pathology in 5×FAD mice
Abstract Microglia play crucial roles in Alzheimer’s disease (AD), yet the molecular mechanisms are unclear. Here, we show that CD31, a recognized endothelial marker, is predominantly expressed in microglia but not in neurons or astrocytes, and it is significantly elevated in the brains of AD patients and mouse models.
Acquired genetic and cell-state changes in IDH-mutant glioma progression
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Abstract Gliomas with mutant isocitrate dehydrogenase (IDH) are malignant brain tumours that typically arise in early to mid-adulthood and nearly always recur following treatment1,2. However, the genetic and cellular-state changes that drive IDH-mutant glioma progression under treatment remain incompletely understood.
By Kevin Johnson, Avishay Spitzer, Frederick S. Varn, Masashi Nomura, Luciano Garofano, Tamrin Chowdhury, Anuja Lipsa, Linbin Zhang, Ester Calvo Fernández, Tanyeri Barak, Samirkumar B. Amin, Emre Kocakavuk, Dacheng Zhao, Fulvio D’Angelo, Simona Migliozzi, Lillian Bussema, Simon Gritsch, Sun Ha Paek, Franck Bielle, Alice Laurenge, Bertrand Mathon, Alberto Picca, Marc Sanson, Ann-Christin Hau, Frank Hertel, Kamil Grzyb, Zheng Zhao, Qianghu Wang, Tao Jiang, Julie Miller, Hiroaki Wakimoto, Daniel Cahill, Jennifer Moliterno, Murat Gunel, Beth Hermes, Nader Sanai, Anna Golebiewska, Simone P Niclou, Jason T. Huse, W. K. Alfred Yung, Anna Lasorella, Mario L. Suvà, Antonio Iavarone, Itay Tirosh, Roel G. W. Verhaak, A. Gulhan Ercan-Sencicek, Ayse Buket Peksen, C. Mircea S. Tesileanu, Hyo-Eun Moon
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Nature
Verified
Author Correction: CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord
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Correction to: Nature https://doi.org/10.1038/s41586-023-06783-1 Published online 31 October 2023 In the version of this article initially published, data from another experimental group were inadvertently entered into the corresponding Source Data table for Extended Data Fig. 9d. The Source Data and figure are now updated in the HTML and PDF versions of the article. The corrected data do not affect the results or conclusions of the paper. About this article Sun, S., Li, J., Wang, S. et al.
By Shuhui Sun, Jiaming Li, Si Ran Wang, Jingyi Li, Jie Ren, Zhaoshi Bao, Le Chang Sun, Xibo Ma, Fangshuo Zheng, Shuai Ma, Liang Sun, Min Wang, Yan Yu, Miyang Ma, Qiaoran Wang, Zhiyuan Chen, He Ma, Xuebao Wang, Zeming Wu, Kaowen Yan, Yuanhan Yang, Yixin Zhang, Sheng Zhang, Jinghui Lei, Zhao-Qian Teng, Chang-Mei Liu, Ge Bai, Yan-Jiang Wang, Jian Li, Xiaoqun Wang, Guoguang Zhao, Tao Jiang, Jing Qu, Weiqi Zhang, Guang-Hui Liu
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Nature
Verified
An Embodied Paper-Based Microfluidic Al-Air Battery for Enduring Untethered Insect-Scale Robots
1 Introduction The unique combination of multimodal locomotion [1, 2] and superior maneuverability [3, 4] in insect-scale robots unlocks new possibilities for missions in confined and structurally sensitive environments. Unlike bulky machinery, these robotics can navigate complex terrains at high speeds with tight turning circles, making them ideal for demanding applications from precision inspection and exploration [5-7] to critical rescue operations [8, 9] and biomedical tasks [10-12].
Enhancing diabetes risk stratification through natural language processing: a multimodal data integration approach
Abstract Background: This study investigates whether integrating Natural Language Processing (NLP) with traditional clinical data improves type 2 diabetes risk prediction by extracting latent risk factors from unstructured medical text. Methods: We analyzed a public dataset of 1,879 individuals.
Integration of tongue image features and tongue coating microbiome for differentiating dampness patterns in MASLD
Abstract Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disorder that can progress to hepatic fibrosis, cirrhosis, and hepatocellular carcinoma. Traditional Chinese medicine (TCM) has therapeutic effects in MASLD. In TCM, dampness patterns predominate in MASLD and are further classified into damp heat (DH) and cold dampness (CD) subtypes based on distinct pathogenic mechanisms.
Research on provincial-level medical insurance coordination in Guangxi’s multi-ethnic regions from the perspective of urban–rural integration
Abstract Objective: This study aims to explore the necessity, model selection, and implementation suggestions for the provincial-level overall planning of basic medical insurance in Guangxi, China, to address the structural imbalance of medical insurance funds and improve the sustainability of the system. Methods: A comparative analysis approach was employed to examine the “unified revenue and expenditure” model and the “adjustment fund” model for provincial-level overall planning.
A Breeze-Driven TENG System Enabling Full-Cycle Charging of Batteries for Distributed Sensors
Yingjin Luo and Andeng Liu contributed equally to this work. Y.Luo, A.Liu, T.Jiang, et al. “A Breeze-Driven TENG System Enabling Full-Cycle Charging of Batteries for Distributed Sensors.” Advanced Functional Materials (2026): e75875. https://doi.org/10.1002/adfm.75875 Conflicts of Interest The authors declare no conflicts of interest.
Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer
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Abstract Serous endometrial cancer (SEC) is an aggressive subtype of endometrial cancer (EC) with poor prognosis and limited treatment options. Here, we develop a clinically relevant, immunocompetent serous-like mouse model incorporating oncogenic PIK3CA mutation, Trp53 loss, and MYC overexpression. Using this model together with human EC cell lines, patient-derived organoids (PDOs), xenografts, and patient datasets, we investigate mechanisms underlying resistance to PI3Kα-targeted therapy.
By Xin Cheng, Yadong Zhang, Guruprasad Ananda, Tao Jiang, Jing Ni, Shaozhen Xie, Hao Gu, Elena Ivanova, Marisa R Nucci, Zhe Wang, Kaifu Chen, Bose Kochupurakkal, Gordon Freeman, Geoffrey I. Shapiro, Joyce Liu, Panagiotis A. Konstantinopoulos, Ursula Matulonis, Jean J. Zhao, Changli Qian, Erica Holdridge, Renlei Ji
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Nature
Verified
STUB1-induced polyubiquitination of SIK3 in alveolar type 2 epithelial cells alleviates severity and outcomes of acute lung injury
Abstract Disruption in alveolar type 2 epithelial cells (AT2s) homeostasis by oxidative stress plays an essential role in the pathogenesis of acute lung injury (ALI). However, significant discrepancies remain in understanding the mechanisms for AT2 as a main target for reactive oxygen species (ROS). Herein, we show that STUB1, an E3 ligase involved in protein homeostasis, was dominantly expressed in AT2s.
MS4A4A promotes macrophages M2 polarization via NF-κB /JAK-STAT6 axis, resulting GBM malignant progression
Abstract The immunosuppressive tumor microenvironment (TME) is a major issue in the malignant progression of glioma patients. The membrane spanning four domains A4A (MS4A4A) has a relationship with M2 polarization of macrophages, and participates in the malignant progression of various cancers. Therefore, exploration of the key role of MS4A4A contributing to glioma biological processes is urgently needed.
Huangjin Shuangshen decoction alleviates chronic atrophic gastritis by suppressing TNF/NF-κB signaling and promoting CFTR-associated gastric mucosal barrier repair
Abstract Background: Chronic atrophic gastritis (CAG) is a precancerous gastric lesion characterized by persistent inflammatory injury, glandular atrophy, and impairment of gastric mucosal barrier-associated integrity. Huangjin Shuangshen Decoction (HJSS) has shown therapeutic potential in gastritis-related disorders, but its effects on CAG and the underlying mechanism remain unclear. This study investigated whether HJSS alleviates CAG by modulating inflammation-associated barrier dysfunction.
Phase change material-based antibacterial nanoparticles for short-term preservation of cooked meat during temperature abuse
Abstract To prevent the rapid microbial growth caused by unintended temperature abuse during the handling of cooked meat, such as malfunctioning hot-holding equipment or improper storage, this study developed a smart formulation that can be triggered by high temperature to release antibacterial agents on demand. A mixture of lauric acid and stearic acid was employed as the phase change material (PCM), and cinnamaldehyde (CA) was used as the active substance to fabricate this composite (CA/PCM).
Synergistic acousto-optical profiling of morphodynamic features for smart detection of acute lymphoblastic leukemia
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Keywords acoustic-optical biosensing label-free detection point-of-care testing acoustic streaming optical Fourier analysis acute lymphoblastic leukemia ALL Introduction Acute lymphoblastic leukemia (ALL) is a life-threatening hematologic malignancy with high mortality, and its 5-year survival rate typically remains below 20%–30%.1,2,3,4 Early screening for ALL, particularly the identification of malignant lymphoblasts, plays a pivotal role in clinical decision-making from initial diagnosis...
By Yifan Wang Verified, Shukun Zhao, Xiaoqi Gao, Yantong Liu, Chen Yang, Tao Jiang, Yihan Ma, Keyu Chen, Hongqiang Jiang, Fuling Zhou, Yi Yang, Xiaotong Si, Shanpeng Dong
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Cell Reports Physical Science
Verified
NR3C1 Modulates Wnt Signalling to Influence the Invasiveness and Immune Features of Nonfunctioning Invasive Pituitary Adenomas
1 Introduction Pituitary adenomas (PAs) are common intracranial tumours, accounting for approximately 15% of all such tumours [1]. They are categorised as functional or non-functional adenomas based on hormone secretion and biological behaviour. Functional adenomas include growth hormone-secreting adenomas, adrenocorticotropic hormone-secreting adenomas and prolactinomas, which cause excessive hormone release and associated clinical manifestations [2].
A New Shape Sensing Approach for Multilayer Composites Beams With Variable Cross-Section Under Nonlinear Deformations
T.Jiang, X.-f.Sun, J.-z.Huang, D.-s.Li, C.-x.Qu, and L.Chen, “A New Shape Sensing Approach for Multilayer Composites Beams With Variable Cross-Section Under Nonlinear Deformations,” International Journal for Numerical Methods in Engineering127, no. 7 (2026): e70323, https://doi.org/10.1002/nme.70323. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author.
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma
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Abstract Posterior fossa type A (PFA) ependymoma is an unusual infantile brain tumour with few known somatic mutations, thought to be driven by epigenetic mechanisms1. PFA ependymoma has a markedly higher incidence and worse prognosis in male children than in female children2. The mechanisms that underlie these sex differences are at present unknown. Here we show that the cellular hierarchy of PFA ependymoma is less differentiated in male individuals than it is in female individuals.
By Winnie Ong, Alexandra Rasnitsyn, Ricardo Gonzalez, Ricardo González, Rodrigo Gutierrez, Rodrigo Gutiérrez Verified, Polina Balin, Amr M. Saadeldin, Xiaochong Wu, Maria C. Vladoiu, Vicente López, Fernando Gonzalez-Salinas, Navneesh Yadav, Dinesh Mohanakrishnan, Hinda Najem, Sebastian Pacheco, Kaitlin Kharas, Cory M Richman, David Przelicki, EVAN WANG, Haipeng Su, Rachel Curry Verified, Runze Yang, Michelle Kameda-Smith, David Scott, Zaili Luo, Mingyang Xia, Namal Abeysundara, Anders Erickson, Ncedile Mankahla, Chu Pan, Raul Climent Suarez, Raúl Tello Suarez, Raúl A. Suárez, Ning Huang, Yihao Wu, Hao Wang, Tajana Douglas, Jonelle G. Pallota, Steven Hebert, Heather Whetstone, Hassaan Maan, Hussein Lakkis, Juyeun Lee, Sadeesh K. Ramakrishnan, Yanxin Pei, Yujie Tang, Frank Lin, Guillermo Aldave, Marco Gallo, Robert M. Friedlander, Faiyaz Notta, Laura Donovan, Murali Chintagumpala, Bo Wang, Yun Li Verified, Zhaolei Zhang, Ying Mao, Wei Hua, Charles G. Eberhart, Calixto-Hope G. Lucas, Sriram Venneti, Poul H Sorensen, Alberto Delaidelli, Wenhao Zhou, Jason Kirk Verified, Dean Tang, Tao Jiang, Hailong Liu, Justin D Lathia, Hiromichi Suzuki, Jeremy Rich, Lincoln D. Stein, Nada Jabado, Vijay Ramaswamy, Q. Lu, Amy B. Heimberger, Craig Daniels, Kulandaimanuvel Antony Michealraj, Claudia L. Kleinman, Bryn Livingston, Krystin Mantione
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Nature
Verified
Development and testing of a smart empowerment education system for gout patients in suburban areas
Abstract Objectives: This study aimed to develop and evaluate an Intelligent Empowerment Education-based System (IEES), which integrates empowerment education, refined management protocols, and smart technologies, for application among gout patients in resource-limited suburban settings. The primary goal was to address key challenges including suboptimal self-management capacity, poor treatment adherence, and unfavorable long-term clinical outcomes.
Clinical Value of Inflammatory Indexes in Predicting Post-Transplantation Prognosis in Hepatocellular Carcinoma: A Retrospective Cohort Study
Back to Journals » Journal of Inflammation Research » Volume 19 Original Research Liver and Gall Bladder Inflammation Authors Wang HX, Ye XY, Jiang T, Lyu SC, He Q , Ji ZL , Lang R Received 20 March 2026 Accepted for publication 18 June 2026 Published 3 July 2026 Volume 2026:19 610101 DOI https://doi.org/10.2147/JIR.S610101 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Fatih Türker Han-xuan Wang1,2,*, Xiao-yong...
A parallel-legged insect-scale robot based on actuation-structure integrated origami mechanism
Abstract Insect-scale robots can access extremely confined spaces, demonstrating significant application potential in fields such as disaster relief and exploration within confined environments. Currently, the integrated fabrication and formation are still a challenge for insect-scale piezoelectric robots. In this study, we propose a 1.2 g novel parallel-legged insect-scale origami robot named PLioBot featuring an integrated origami mechanism.
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